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In vitro Şartlarda Mutant AVPR2 Proteinlerinin Yarı Ömür ve Glikozilasyon Özelliklerinin Araştırılması
(Fen Bilimleri Enstitüsü, 2020)
Diabetes insipidus (DI) is a disease characterized by excessive urine formation (polyuria) and excessive thirst (polydipsia). DI is classified into gestational DI, primary polydipsia, Nephrogenic DI (NDI), and Central DI ...
Drosophila melanogaster’de Srl Geninin Egzersiz Fizyolojisi Yanıtlarını Etkileyen Genetik Elementlerin Genom Boylu İlişkilendirme Çalışması ile Saptanması
(Fen Bilimleri Enstitüsü, 2020)
In this thesis, it is aimed to determine the processes that affect the expression of the spargel (srl) gene, which is known to have an important role in exercise physiology, and the genes it interacts with. The srl gene, ...
Drosophıla melanogaster’de Egzersiz Performansı ile İlişkili Ampdeam Geni ile Etkileşen Genomik Varyantların Saptanması
(Fen Bilimleri Enstitüsü, 2020)
In this thesis, it is aimed to find out the genes that interact with the AMPdeam gene which
has been proven to be associated with exercise performance responses and energy
metabolism, in Drosophila melanogaster. For this ...
Kalıtsal Metabolik Hastalıklarda Antioksidan Yanıt ve Otofajinin P62/Nrf2/Keap1 Yolağı Aracılığıyla Araştırılması
(Fen Bilimleri Enstitüsü, 2020-07-08)
Due to the enzyme, enzyme cofactor, carrier deficiency or disorder in the metabolic pathways, Inherited Metabolic Diseases (IMDs) cause the accumulation of the substrate and / or end product deficiency that are the single ...
Diyabet Modeli Oluşturulan Ins-1e Pankreas Beta Hücrelerinde Neoeriositrinin Koruyucu Etkisinin Araştırılması
(Fen Bilimleri Enstitüsü, 2020)
Diabetes is a very common metabolic disease and its incidence has been increasing. In
addition to use of drugs in diabetes treatment, plant-based antidiabetic products are also
used as alternative. Phytotherapeutic ...
Ankara İli Buprestıdae (Insecta: Coleoptera) Familyası Üzerinde Sistematik Araştırmalar
(Fen Bilimleri Enstitüsü, 2020)
In this study, researches were carried out on the family Buprestidae in Ankara province. For this purpose, a total of 69 days of field studies were conducted, 33 days in May-October 2018 and 36 days in April-October 2019. ...
Ankara İli Coccınellıdae (Insecta: Coleoptera) Familyası Üzerinde Sistematik Araştırmalar
(Fen Bilimleri Enstitüsü, 2020)
In this study, researches was conducted on the family Coccinellidae (Coleoptera) in Ankara province. For this purpose, field studies were carried out in May-October 2018 and April-October 2019 in Ankara. 5310 specimens ...
Karragenanın İnsan Meme Kanseri Hücre Hatlarında Sitotoksik Etkisinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2021-05-27)
In this thesis stage, the dose and time dependent cytotoxic effects of carrageenan on
MCF-7, MDA-MB-231, SKBR-3 breast cancer cell lines and healthy breast epithelial
cell line SVCT were investigated.
Carregenan is a ...
E Vitamininin A-Tokoferol ve A-Tokotrıenol Formlarının Beyinde Oluşan Beta Amıloıd Plak Birikimine Karşı Koruyucu Etkilerinin Karşılaştırılması
(Fen Bilimleri Enstitüsü, 2021)
In this thesis study, the protective effects of α-tocopherol and α-tocotrienol forms of vitamin E, a powerful antioxidant, against beta amyloid-induced neurodegeneration were experimentally investigated and compared on a ...
Kızılçam’da (Pınus Brutıa Ten.) Yangınla İlişkili Karakterlerin Popülasyonlar Arası Değişkenliği ve Bu Değişkenliği Ortaya Çıkartan Faktörler
(Fen Bilimleri Enstitüsü, 2021)
In Mediterranean type ecosystems, Pinus genus species have many characters adapt to fire regimes. These characters are known to have variability between species, geographic areas, populations, and even individuals. In this ...