Bölüm "Pediatrik Temel Bilimler" için listeleme
Toplam kayıt 20, listelenen: 1-20
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ADAM19, FAM13A, IREB2 Genleri Yaygın Varyantlarının KOAH Yatkınlığı ve Şiddeti ile İlişkisi
(Sağlık Bilimleri Enstitüsü, 2022)Chronic obstructive pulmonary disease (COPD) is a heterogenous disease characterized by persistent airway limitation caused by both genetic predisposition and environmental factors. In this study, we aimed to investigate ... -
Ailevi Akdeniz Ateşi Hastalarında Otoenflamasyonun İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023)Familial Mediterranean Fever (FMF) is the most common autoinflammatory disease. The aim of this study is to determine the changes of GSDMD, IL-1B, and IL-18 in disease attacks of FMF and to compare their levels in the ... -
Akne vulgarisli hastalarda tümör nekrozis faktör α-308 G/A ve interlökin 1 β- 511 C/T polimorfizmlerinin incelenmesi
(Sağlık Bilimleri Enstitüsü, 2017-11-22)Acne is a chronic inflammatory skin disorder which varies in severity in each individual and which may heal with scarring that lead deformities hard to treat. Tumor necrosis factor alpha (TNF α) and interleukin 1 β (IL-1β) ... -
Annelerı̇n çalışma durumu ve statüsüne göre emzı̇rı̇lmenı̇n sürdürülmesı̇: tnsa verı̇lerı̇nı̇n ı̇kı̇ncı̇l analı̇zı̇
(Sağlık Bilimleri Enstitüsü, 2023)Çiçek Ş. Duration of breastfeeding according to employment status and profession of mothers: Secondary analysis of Turkish Population Health Survey data. Hacettepe University Graduate School of Health Sciences, Social ... -
DOCK8 Eksikliği Olan Hastalarda T Hücre Reseptör Repertuvarının Yeni Nesil Dizileme İle Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2022)Identification of immüne repertoire is crucial to characterize adaptive immüne responses in terms of disease approach. V(D)J recombination is one of the most crucial factors in the development of the immune repertoire. ... -
Dynamics of the Rhomboid-Like Protein Rhbdd2 Expression in Mouse Retina And Involvement of Its Human Ortholog in Retinitis Pigmentosa
(Amer Soc Biochemistry Molecular Biology Inc, 2013)The novel rhomboid-like protein RHBDD2 is distantly related to rhomboid proteins, a group of highly specialized membrane-bound proteases that catalyze regulated intramembrane proteolysis. In retina, RHBDD2 is expressed ... -
Effects of Respiration on Left Ventricular Diastolic Function in Healthy Children
(The European Society of Cardiology, 1996)Pulsed Doppler echocardiographic indices of mitral valve filling were measured in 20 healthy children, between 3 and 125 years old, in order to evaluate the effects of spontaneous respiration on left ventricular diastolic ... -
Investigating the Effects of Neurometabolic Disease-Causing Genes on Synapse Function in Drosophila melanogaster
(Sağlık Bilimleri Enstitüsü, 2022)Our group has identified several patients that harbor mutations in genes that hold the potential for being important players of synapse function, UNC79 and MBOAT7 being two of them. UNC79 is one of the accessory ... -
Kord Kanındaki Kemokin Düzeylerinin Prematüre Bebeklerdeki Oksidatif Stres Kaynaklı Morbiditeler ile İlişkisi
(Sağlık Bilimleri Enstitüsü, 2023)Oxidative stress occurs when free radicals increase and exceed the levels of antioxidant mechanisms that can neutralize them. It causes tissue damage by causing protein, lipid and polysaccharide oxidation, DNA fragmentation, ... -
Molecular Characterization Of Turkish Patients With Pyrimidine 5 ' Nucleotidase-I Deficiency
(Amer Soc Hematology, 2003)Pyrimidine 5' nucleotidase-I (P5N-I) deficiency is a rare autosomal recessive disorder associated with hemolytic anemia, marked basophilic stippling, and accumulation of high concentrations of pyrimidine nucleotides within ... -
Myocilin Mt1 Promoter Polymorphism In Turkish Patients With Primary Open Angle Glaucoma
(Molecular Vision, 2005)Purpose: To evaluate the association of the myocilin gene promoter variant -1000C>G (MYOC.mt1) with primary open angle glaucoma (POAG) and its possible role on the phenotype and the severity of glaucoma in Turkish patients. ... -
Novel Alu Retrotransposon Insertion Leading To Alstrom Syndrome
(Springer, 2012)Alstrom syndrome is a clinically complex disorder characterized by childhood retinal degeneration leading to blindness, sensorineural hearing loss, obesity, type 2 diabetes mellitus, cardiomyopathy, systemic fibrosis, and ... -
PFAPA Hastalarında Behçet Hastaları ile Karşılaştırmalı Olarak NETozis, Düşük Dansiteli Nötrofiller ve Doğal Lenfoid Hücrelerin Değerlendirilmesi.
(Çocuk Sağlığı Enstitüsü, 2024)PFAPA (Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis) Syndrome is an autoinflammatory disease characterized by recurrent fever, aphthous stomatitis, pharyngitis, and cervical lymphadenitis, primarily ... -
Prematüre bebeklerde prenatal Doppler Ultrasonografi bulguları ile postnatal serebral Near-Infrared Spektroskopi (NIRS) ölçümlerinin uyumluluğunun araştırılması
(Sağlık Bilimleri Enstitüsü, 2023-06-19)Perinatal and neonatal surveillance of intrauterine growth restriction (IUGR) has gained importance due to its negative impacts on cerebral oxygenation. In this thesis study, it was aimed to compare fetal cerebral and ... -
Primer İmmün Yetmezlikler-İşlevsel Çözümleme
(Çocuk Sağlığı Enstitüsü, 2023-06)Primary immunodeficiency diseases are rare diseases with a wide spectrum due to the increasing the number of new mutations defined to cause these diseases. Besides the clinical and laboratory manifestations, the genetic ... -
Retinitis Pigmentosa Caused By Mutations in the Ciliary MAK Gene is Relatively Mild and is not Associated with Apparent Extra-Ocular Features
(Wiley, 2015)Purpose: Defects in MAK, encoding a protein localized to the photoreceptor connecting cilium, have recently been associated with autosomal recessive retinitis pigmentosa (RP). The aim of this study is to describe our ... -
Sesamum İndicum L. (Susam) X Papaver Somniferum L. (Haşhaş) Arasındaki Çapraz Reaksiyonların Western Blot Yöntemi ile Gösterilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Yıldız D., Determination Of The Cross Reaction Between Sesamum indicum L. x Papaver somniferum L. With Western Blott Method Hacettepe University Graduate School of Health Sciences Molecular and Immunological Basics of ... -
Streptococcus Pneumonıa, Staphylococcus Aureus ve Pseudomonas Aerugınosa ile İnvaziv Bakteriyel Enfeksiyon Geçiren Çocuklarda Irak4 ve Myd88 Genlerinde Mutasyon Varlığının Araştırılması
(Çocuk Sağlığı Enstitüsü, 2023-08)Invasive bacterial infections are bacterial infections of sterile body fluids. Invasive bacterial infections include meningitis, bacteremia, sepsis, septic arthritis, osteomyelitis, pleural empyema, deep tissue and organ ... -
Unilateral Pterjium Olgularında Gözyaşı Sitokin Seviyesinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2019)The aim of this study is to determine proinflammatory and antiinflammatory cytokine levels and growth factor concentrations in tear samples of pterygium cases and thus to contribute to the elucidation of the immunological ... -
Vankomisine Bağlı Kırmızı Boyun Sendromu Geliştiren Hastalarda Mrgprx2 Reseptör Mutasyonlarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023-08-23)Vancomycin is a tricyclic glycopeptide antibiotic effective against Gram-positive bacteria, isolated from the bacterial species Amycolatopsis orientalis. Vancomycin use can lead to two types of hypersensitivity reactions: ...