MİKOZİS FUNGOİDES, PSORİASİS VE ATOPİK DERMATİT HASTALARINDA DERMOSKOPİK BULGULARIN İNCELENMESİ

Abstract

Balan B. K. Dermoscopic Evaluation of Patients with Mycosis Fungoides, Psoriasis, and Atopic Dermatitis. Hacettepe University Faculty of Medicine, Department of Dermatology and Venereology, Medical Specialty Thesis. Ankara, 2025. Mycosis fungoides (MF), psoriasis (PSO), and atopic dermatitis (AD) are chronic skin diseases with overlapping clinical features. This study aimed to compare dermoscopic findings among these three conditions and to identify diagnostic features that may assist in clinical differentiation. A total of 159 patients (MF n: 55, PSO n: 53, AD n: 51) were included. Dermoscopic evaluation was performed in all patients, and findings were compared based on defined parameters. Linear and spermatozoa-like vessels were significantly more frequent in MF and AD, while dotted vessels were predominant in PSO (p < 0.001). Uniform vascular distribution was common in PSO, whereas clustered or nonspecific patterns were more frequently observed in MF and AD (p < 0.001). Polymorphous vascular patterns were significantly more common in MF and AD and rare in PSO (p < 0.001). Although scale was present in all groups, it typically followed skin furrows in MF and appeared orange in AD (p < 0.001). Focal white structureless areas and focal orange discoloration were significantly more common in MF, while ulceration and dystrophic hairs were predominant in AD (p < 0.001). A bright red background was characteristic in PSO, whereas pink or pale red backgrounds were more frequent in MF and AD (p < 0.001). Ultraviolet (UV) mode dermoscopy enhanced the visualization of scale and structureless areas in all groups. This study quantitatively compared dermoscopic findings in MF, PSO, and AD for the first time at this scale, revealing distinct vascular and structural patterns. The presence of linear and spermatozoa-like vessels and focal orange discoloration in MF, along with orange scales and ulceration in AD, may provide valuable diagnostic clues.