Browsing Dahili Tıp Bilimleri Bölümü by Funding "Bilimsel Araştırma Projeleri KB"
Now showing items 1-20 of 73
-
90y Mikroküre Tedavisinde Anjiyojenik Faktör Düzeyleri ile Prognoz Arasındaki İlişkinin Araştırılması
(Tıp Fakültesi, 2022)Tumor angiogenesis is a crucial process in cancer and one of the main determinants of the growth, invasion and metastasis potential of the tumor. Better-performing markers are needed for patient selection and prognosis ... -
Agmatinin Deneysel Sıçan Septik Şok Modelinde Bozulmuş Vasküler Yanıta Etkisi
(Tıp Fakültesi, 2023)Sepsis is the inflammatory response of the host to pathogen. Regardless of the severity of inflammation, mortality is observed as a result of impaired hemodynamic homeostasis-mediated organ dysfunction. Therefore, treatment ... -
Ailesel Hiperkolesteroleminin Genetik Nedenlerinin Araştırılması
(Tıp Fakültesi, 2022)Familial hypercholesterolemia is a genetic disease characterized by high plasma cholesterol levels and early cardiovascular disease development. Main objectives of the study were to evaluate the genetic causes of familial ... -
Akromegali ve Prolaktinoma Tanılı Hastalarda Kardiyak Steatozis, Kardiyovasküler Risk ve İlişkili Biyomarkerlar
(Tıp Fakültesi, 2020)In systemic diseases, early recognition of dysfunctions related to cardiovascular complications is important. The aim of the current study was to assess the relationship of four-dimensional echocardiographic measurements ... -
Alamandinin Lipopolisakkarit ile İndüklenmiş Sıçan Sepsis Modelinde Vasküler ve Renal Fonksiyonlara Etkisi
(Sağlık Bilimleri Enstitüsü, 2024)Sepsis is defined as uncontrolled inflammation leading to multiple organ system failure and dysfuncion. Acute kidney injury is an important cause of significant morbidity and mortality in sepsis. Alamandine (ALA) is a ... -
Alfa-Sinüklein Fibrili ile Oluşturulan Parkinson Hastalığı Sıçan Modelinde Alfa-Sinüklein Patolojisinin Şiddet ve Dağılımında Glimfatik Sistemin Rolü
(Tıp Fakültesi, 2022-09-06)Parkinson's disease (PD) is the second most common neurodegenerative disease and its prevalence increases in the aging population. Neurotoxicity of α-synuclein (α-syn) pathological accumulations and dopaminergic cell loss ... -
Alzheimer Hastalığında Sirkadiyen Ritm Değişikliği ve Morfolojik Karşılığının İncelenmesi
(Tıp Fakültesi, 2020)Alzheimer Disease (AD) is the most common form of dementia in the elderly and with growing of aging population gains importance by means of raising individual disability and the costs of health and daily care settings. ... -
Ankilozan Spondilit Hastalarında, Ciddi Spinal Tutulum ile İlişkili Klinik, Demografik Özellikler ve HLA Allellerinin İncelenmesi
(Tıp Fakültesi, 2023-09)Our aims in this study are; comparing the frequencies of HLA alleles in ankylosing spondylitis (AS) patients in Turkish society is to identify alleles that may be associated with disease severity and severe spinal involvement ... -
Anne sütünde bisfenol a ve d vitamini düzeyleri arasındaki ilişki
(Sağlık Bilimleri Enstitüsü, 2023-02-13)An endocrine disruptor Bisphenol A (BPA) is widely used in daily life and it is suggested that one of its negative effects on human health may be on vitamin D (vitD) metabolism. In this study, it was aimed to investigate ... -
Antibiyotik Tedavisi Alan Yenidoğanlarda Probiyotik Desteğinin İdrar D-Laktik Asit Düzeyi Üzerine Etkisinin İncelemesi
(Tıp Fakültesi, 2021)Tabur Y. Investigation of the effect of probiotic supplementation on urinary D-lactic acid level in newborns receiving antibiotic treatment. Hacettepe University Faculty of Medicine, Department of Child Health and Diseases, ... -
Benign ve malign kas-iskelet sistemi tümörlerinin ayrımında monoeksponansiyel difüzyon ağırlıklı görüntüleme, intravoxel incoherent motion ve difüzyon kurtozis modellerinin kullanıldığı multiparametrik yaklaşım
(Tıp Fakültesi, 2021)The aim of our study was to evaluate the value of multiparametric analysis of monoexponential DWI, IVIM and DK models for differentiating benign and malignant musculoskeletal tumors. Between Aug 2019 to Nov 2020, a total ... -
Bilinen Metabolik Hastalıklar ve Sendromlar ile İlişkilendirilemeyen Konjenital/Gelişimsel Kataraktlarda Yeni Nesil Dizileme ile Moleküler Etiyolojinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)The aim of the study was to identify the molecular etiology in patients with congenital/developmental cataract which can not be attributed to known metabolic diseases or syndromes by next generation sequencing. A total of ... -
Çocuk Acil Servisine Akut Karın Ağrısı Nedeni İle Başvuran Hastalarda Klinik Önemli Abdominal Patolojiyi Belirleyen Faktörlerin Prospektif Olarak İncelenmesi
(Tıp Fakültesi, 2024)DAŞLI, E. Evaluation of factors determining clinically significant abdominal pathology in patients presenting to the pediatric emergency department with acute abdominal pain. Hacettepe University Faculty of Medicine, ... -
Çocuk Yoğun Bakım Hastalarında Kullanılan Tıbbi Malzemelerin İdrar Bisfenol A Düzeylerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2020-10-01)The exposure of pediatric intensive care patients to Bisphenol A may be different in acute sick children who were healthy beforehand, and chronically sick children, due to the use of multiple and various medical materials. ... -
Çocuklarda Konuşma Gecikmesi ile Plazma Ftalat Düzeyi Arasındaki İlişkinin İncelenmesi
(Tıp Fakültesi, 2020)Speech delay is one of the most common developmental problems seen in preschool children. Therefore, being able to diagnose and identify underlying causes and risk factors is very important for timely intervention and ... -
Çocukluk Çağı Otozomal Dominant ve Otozomal Resesif Polikistik Böbrek Hastalıklarının Klinik ve Genetik Özelliklerinin Araştırılması
(Tıp Fakültesi, 2021-02-19)Tutal, O, Clinical and Mutational Spectrum of Children with Autosomal Recessive and Autosomal Dominant Polycystic Kidney Disease, Hacettepe University Faculty of Medicine, Department of Pediatrics, Thesis of Pediatrics, ... -
Diyabetik Ayak Gelişen Hastalarda Angiopoietin Benzeri Protein-4 ve Follistatin Benzeri 1 Protein Düzeyleri ile Angiopoietin Benzeri Protein-4 Gen Polimorfizmi
(Tıp Fakültesi, 2019)Angiopoietin-like protein-4 (ANGPTL-4) is an angiopoietin-like protein that plays an important role in wound healing, lipid, and glucose metabolism. Follistatin-like 1 (FSTL1) is a cardiokin with effects on angiogenesis ... -
Diyabetik Ketoasidozlu Hastalarda Miyokin Profilinin Değerlendirilmesi
(Tıp Fakültesi, 2023)The effects of myokines mainly released from the muscle tissue on glucose and lipid metabolism are still under investigation, and their roles in the pathogenesis of diabetic ketoacidosis (DKA) are yet unknown. In this ... -
DOCK8 Eksikliği Olan Hastalarda T Hücre Reseptör Repertuvarının Yeni Nesil Dizileme İle Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2022)Identification of immüne repertoire is crucial to characterize adaptive immüne responses in terms of disease approach. V(D)J recombination is one of the most crucial factors in the development of the immune repertoire. ... -
Epilepsi Hastalarında, Serum ve Beyin Omurilik Sıvısındaki Oreksin Seviyesinin Uyku Evreleri ve Nöbetlerle İlişkisi
(Tıp Fakültesi, 2020)One of the unknown mechanisms in epilepsy pathogenesis is protein called orexin. Although the relation of orexin to sleep has been revealed, its place in epilepsy has not been fully clarified yet. In this study, we aimed ...
