Larinks Kanserinin Evrelemesinde Pre-Operatif BT ve Radyolog Deneyiminin Etkisi

Abstract

The aim of this study was to evaluate the prognostic value of preoperative computed tomography scan in patients with laryngeal cancer in respect to the presence of prior radiotherapy, level of cartilage ossification and the effect of the experience of the radiologist. CT scans of 51 patients who had undergone total laryngectomy between 2003 and 2013 were evaluated retrospectively. The patients were subdivided into two groups according to whether they had received any treatment before surgery. There were 34 patients who did not have any prior treatment and the second group consisted of 17 patients who had received prior RT. Two independent observers evaluated the CT scans according to paraglottic and preepiglottic space invasion, thyroarytenoid gap widening, extralaryngeal spread, cartilage invasion and nodal metastases. The measurement of tumour volume and assesment of cartilage ossification were also performed. The preoperatif CT scans were compared with the pathology reports of the specimens taken in the surgery in respect to the presence of extralaryngeal spread, cartilage invasion and nodal metastases. The effect of patient age in the CT diagnosis of nodal metastases was also assessed. Mc-Nemar test, Ki-square and kappa value tests were used in statistical analysis. There was no statistical difference between the two radiologists' CT evaluations. The prognostic value of computed tomography in the detection of thyroid cartilages invasion had a sensitivity of %90, and a specificity of %71.4; the same parameters were as %49 and %92 for extralaryngeal spread. These values were similar to the reported values in the literature. In the patients who had not received RT preoperatively, the prognostic value of CT was higher than the patients who received RT preoperatively. Similarly the value of CT was higher in patients who had advanced cartilage osssification (p= 0.005).