Browsing Fen Bilimleri Enstitüsü Tez Koleksiyonu by Funding "TÜBİTAK"
Now showing items 1-20 of 23
-
Abdominal Cerrahide Kullanılmak Üzere PHBHHx Membranların Hazırlanması ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2024)Approximately 90% of patients develop peritoneal adhesions during the recovery process following abdominal surgery. Adhesions are abnormal fibrous or scar tissue resulting from the healing process. To prevent adhesions, ... -
Alt-Birim Protein Antijenlerinin İmmunojenitesini Artırmak Amacıyla Yeni Adjuvant/Taşıyıcı Sistemlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021-07-22)Infectious diseases encompass 25% of deaths in the world per year. The most effective approach in preventing deaths is vaccination. However, at present, the availability of vaccines for many infectious diseases is still ... -
Anjiyogenik Mikroiğnelerin Geliştirilmesi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2024)Angiogenesis plays a crucial role in tissue repair processes, ensuring the continuation of important cellular processes as stem cell differentiation, cell proliferation, and migration during tissue repair. It also plays a ... -
Antimikrobiyal Peptit ve Antibiyotik Kombinasyonu İçeren Lipozom Formülasyonlarının Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2024)In the treatment of infections caused by microorganisms, active substances are referred to as antimicrobial therapeutics. Due to the increasing resistance to antimicrobial therapeutics in recent years, AMPs have emerged ... -
Deselülerize Miyokard-Elastomer Yamaların Hazırlanması ve In Vitro Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2021)Heart failure is the final stage of most cardiovascular diseases, such as myocardial infarction. Unlike other tissues such as bone and skin, heart tissue does not have the ability to regenerate and repair itself. This ... -
Development of Jak1 Sirna Medıated Nanotherapeutıcs for Non-Melanoma Skın Cancer Therapy
(Fen Bilimleri Enstitüsü, 2021-06)Non-melanoma skin cancer is one of the most common cancers with still no effective treatment. Due to the side effects observed after long and high dose treatments and acquired resistance to the chemotherapy drugs, different ... -
Fenilketonüri Hastalığının Erken Teşhisi ve Takibi için Disk Tabanlı Hasta Başı Tanı Sisteminin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021-12)Phenylketonuria (PKU) is an autosomal recessive metabolic disease due to dysfunction of phenylalanine hydroxylase (PAH) enzyme, which converts phenylalanine (Phe) amino acid to tyrosine amino acid. Phe amino acid and ... -
Fonksiyonel Pet Nano Fiberlerin Üretilmesi ve Yara Örtüsü Olarak Kullanmak Üzere Modifiye Edilmiş Pet Fiberlere Protein Kaplı Gümüş Nanoparçacıkların Adsorpsiyonu
(Fen Bilimleri Enstitüsü, 2020)In this study, silver nanoparticles (S-AgNPs) coated with sericin were adsorbed on poly (ethylene terephthalate)-g-poly(hydroxyethylmethacrylate) (PET-g-HEMA) nanofibres and the use of the obtained material as wound dressing ... -
Fotovoltaik Uygulamalar için CZTS (Cu2SnZnS4) İnce Filmlerin Sentezi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2022)Today, thin-film-based photovoltaic (PV) structures attract attention in the search for alternatives to Si-based solar cells. Among the thin films, the Cu2ZnSnS4 (CZTS) compound is the most remarkable with its optical and ... -
Hücresizleştirilmiş Sığır Gözü Kası ve Pclkas Matriksi Kompozit Doku İskeleleriyle Göz Kası Rejenerasyonu
(Fen Bilimleri Enstitüsü, 2021)This study has been financially supported by TÜBİTAK under the project named "Extraocular Muscle Regeneration by Decellurized Bovine Extraocular Muscle and PCL-Extraocular Muscle Matrix Composite Tissue Skeleton" (1002 ... -
Investigation of The Effects of Perceptual Salience on Target Tracking Behavior Performance of Zebrafish During Rheotaxis
(Fen Bilimleri Enstitüsü, 2024-09-06)Zebrafish (Danio rerio) are freshwater fish inhabiting rivers and lakes in the South Asian region. During their behavior known as rheotaxis, they exhibit a tendency to orient their bodies againts the water flow, thereby ... -
İmplant Kaynaklı Enfeksiyon Etkeni Olan Staphylococcus Epidermidis’e Özgü Aptamer Geliştirilmesi ve Aptamerin Biyofilm Oluşumuna Etkisinin İn Vitro Koşullarda İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)One of the biggest problems encountered in the clinic regarding biomaterials that replace tissues or organs damaged or lost because of accidents along with various diseases is the occurrence of infection. Staphylococcus ... -
Konjenital Septal Defektlerin Onarımına Yönelik Perikard Bazlı Rejeneratif Kardiyak Yamaların Doku Mühendisliği Yöntemi ile Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2021-06)Cardiac patch has been used in the treatment of congenital heart disease and myocardial infarction (MI) while an ideal cardiac patch has not been developed yet. This study aimed to engineer regenerative cardiac patches by ... -
Küçük Hücreli Dışı Akciğer Kanseri için Kannabinoid Yüklü İlaç Taşıma Sistemlerinin Geliştirilmesi ve Validasyonu
(Fen Bilimleri Enstitüsü, 2025)Lung cancer has a high mortality rate worldwide with its advanced invasive behavior and metastatic capacity. FDA-approved or currently tested targeted agents inhibit PI3K/Akt, Ras/MEK/Erk and JNK pathways but with low ... -
Maksillofasiyal Travma Tedavisi İçin Isı ile Şekillendirilebilen Kompozit Kemik Plakalarının Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2024-07)Facial bone fractures (nose fractures, lower jaw fractures, upper jaw fractures, cheekbone fractures) resulting from facial injuries resulting from severe trauma can be treated using plate and screw systems. Depending on ... -
Manyetik Alanla Sürülebilen Temassız Nano-Jeneratör Üretimi ve Özelliklerinin Araştırılması
(Fen Bilimleri Enstitüsü, 2024-12-13)This study aimed to produce and investigate the properties of a nanogenerator driven by AC and DC magnetic fields, utilizing ZnO nanowire array as the bottom electrode and two different top electrodes with pyramidal ... -
Moleküler Dinamik Simülasyonlarında Dissipatif Kuvvetin Yaptığı İşin Hesaplanması
(Fen Bilimleri Enstitüsü, 2022)Although it is quite difficult to model friction on the atomic scale, recent theoretical and experimental techniques have enabled the study of friction at atomic scales, which could not be studied with conventional models ... -
Pankreas Kanseri Kombine Fototermal/Kemo Terapisinde Altın Nanopartiküllerle Dekore Edilmiş Sıcaklığa Duyarlı Lipozomların Kullanım Potansiyelinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2023)Pancreatic cancer is a highly fatal disease with a 5-year survival rate of 4-8% and a mortality rate of 98%. The incidence and mortality rates of this disease are increasing and it is predicted to be the second leading ... -
Plateletçe Zengin Plazmanın Ayrımı İçin Disk Tabanlı Bir Sistemin Tasarımı ve Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2020) -
Radyoterapide Kullanılmak Üzere Kuantum Noktaları ve Fotoduyarlaştırıcı İçeren Tümöre Spesifik Nanoboyutlu Lipozomların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2020-07-08)Cancer is the second most common cause of death in the world. Common approaches in cancer treatment include surgery, radiotherapy, chemotherapy, hormone therapy, immune therapy, and targeted therapy. In radiotherapy, which ...
