Dosya Biçimi"Yok" Kanser Enstitüsü Tez Koleksiyonu için listeleme
Toplam kayıt 15, listelenen: 1-15
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Akciğer Kanser Hücrelerinden Salınan Eksozomların Makrofaj Polarizasyonuna ve Fonksiyonlarına Etkisinin Araştırılması
(Kanser Enstitüsü, 2021)Lung cancer has the highest mortality rate in both men and women worldwide. With our developing technology and knowledge, the research of methods in cancer targeted treatments have turned to target such as tumor microenvironment, ... -
Akciğer Kanseri ve Sol Meme Radyoterapisinde Kardiyak Altyapı Marjlarının Oluşturulması ve Tedavi Planı Optimizasyonu
(Kanser Enstitüsü, 2023)In thoracic irradiations, the coronary arteries (CA) are involuntarily exposed to radiation and subsequent cardiovascular toxicities may occur. To avoid this, the importance of accurately creating the safety margins (SM) ... -
Bortezomib ve İmatinib'in Pankreas Kanserinde Olası Sinerjistik Etkisinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-05-22)The high mortality rate among pancreatic cancer patients underlines the importance of proper treatment. However, the traditional treatment strategies remain inadequate indicating that alternative therapy options need to ... -
Functions of the Activation Induced Cytidine Deaminase (AID) and Toll-like Receptors (TLR) on Regulation of the Central B cell Tolerance Checkpoint
(Sağlık Bilimleri Enstitüsü, 2022-09)Çakan, E., Functions of the Activation Induced Cytidine Deaminase (AID) and Toll-Like Receptors (TLR) on Regulation of the Central B Cell Tolerance Checkpoint, Hacettepe University Graduate School Health Sciences Program ... -
Hacettepe Üniversitesi Onkoloji Hastanesinde Yatmakta Olan Hastalara Bakım Verenlerin Sosyodemografik Özelliklerinin ve Yaşam Kalitelerinin, Hastaların Yaşam Kalitesi Üzerine Etkisi
(Kanser Enstitüsü, 2022)Güner Üliç. P., The Effects of Sociodemographic Characteristics and Quality Of Life of Caregivers on Quality of Life of Inpatient Cancer Patients in Hacettepe University Oncology Hospital, Hacettepe University Graduate ... -
INVESTIGATION OF BIOMARKER POTENTIAL OF FGF RECEPTOR IN BREAST CANCER MODELS
(Kanser Enstitüsü, 2024)Breast cancer is a molecularly heterogeneous disease in which prognosis can be significantly improved through biomarker-driven targeted therapies. The aberration of fibroblast growth factor receptor (FGFR) signaling has ... -
İnsan Makrofajlarında Nitrik Oksit Sentaz 2 (Nos2) İfade ve Aktivitesinin Bazal Benzeri Meme Kanseri Hücrelerinden Üretilen Faktörler Varlığında İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2022)Macrophages are the leading cells of innate immunity in the immune response against pathogens and are involved in the regulation of adaptive immune responses. Macrophages with microbicidal properties promote the proinflammatory ... -
Meme Kanserinde, Il-1β ile Tetiklenen Epitelyal Mezenkimal Dönüşümde Hücre İskeleti Dinamiklerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023-03)The presence of interleukin (IL)-1β, a proinflammatory cytokine, has been demonstrated in the breast cancer microenvironment. IL-1β supports cell survival, proliferation, adhesion, invasion, and migration mechanisms. It ... -
Pankreas Kanseri Hücre Hattında TFAM Ekspresyon Düzeyinin Hücre Fonksiyonları Üzerine Etkisi
(Kanser Enstitüsü, 2022-07-29)Pancreatic cancer is an aggressive malignancy with a poor prognosis. Early diagnosis and application of tumor-specific treatment are very important in pancreatic cancer. Therefore, new biomarkers are needed in the diagnosis ... -
Pankreas Kanserinde Nectin-2 Ekspresyonu ile Sitotoksik T Hücre Fonksiyonları Arasındaki İlişki
(Kanser Enstitüsü, 2023)Checkpoint inhibitors such as anti-CTLA-4, anti-PD1 and anti-PDL-1 are used in the treatment of various cancers. However, they cannot be used in pancreatic cancer due to the lack of PDL-1 expression. Other checkpoint ... -
Prostat Ve Akciğer Kanserlerinin Vmat (Volümetrik Ayarlı Radyoterapi) ve Yart (Yoğunluk Ayarlı Radyoterapi) Tabanlı Tedavilerinde Termal Fotonötron Kontaminasyonunun İncelenmesi
(Kanser Enstitüsü, 2022)Yılmaz, E. Investigation of Thermal Photoneutron Contamination in VMAT (Volumetric Modulated Arc Therapy) and IMRT (Intensity-Modulated Radiation Therapy)-Based Treatments of Prostate and Lung Cancers, Hacettepe University ... -
Racial Disparity in Tumor Microenvironment and Outcomes in Residual Breast Cancer after Neoadjuvant Chemotherapy
(Kanser Enstitüsü, 2023-06-12)Black patients with residual estrogen receptor-positive (ER+) breast cancer after neoadjuvant chemotherapy (NAC) have inferior survival compared to white women resulting racial disparity in breast cancer survival. Differences ... -
The Role of Regnase-1 Protein in Sculpting of Tumor Microenvironment
(Kanser Enstitüsü, 2021)The tumor microenvironment (TME) contains cancer-associated fibroblasts (CAFs) and their tumor-supportive role helps to build an environment in favor of cancer cell progression. Recent researches have revealed that targeting ... -
Tip-1 Yardımcı T (Th1) Hücrelerin Radyasyon Stresi Altında Fonksiyonel ve Fenotipik Değişimlerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2022-07-18)It's critical to understand changes in the functional and phenotypic status of T cells, which play a key role in the anti-tumor response due to the immunosuppressive environment in the tumor microenvironment. In chronic ... -
Β-Catenın N-Terminal Bölge Değişikliklerinin Neoplastik Süreçlerdeki Rolünün Araştırılması
(Kanser Enstitüsü, 2021)Uzun, S, Investigation of The Role of β-catenin N-terminal Domain Alterations in Neoplastic Processes, Hacettepe University Graduate School of Health Sciences Tumor Biology and Immunology Program Doctor of Philosophy ...
