Browsing Biyomühendislik Bölümü Tez Koleksiyonu by Title
Now showing items 44-63 of 96
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Kanser Hücrelerinin Aptamer ve Antibadi Taşıyan Manyetik Nanopartiküller ile Hedeflenmesi
(Fen Bilimleri Enstitüsü, 2014)Within the context of this thesis, developing of an early diagnosis nanoparticular system in order to detect and image human breast cancer cell line of MDA MB 231 is aimed. In this regard, gold coated superparamagnetic ... -
Kanser Tedavisinde Gen Susturulması İçin Hyalüronik Asit-Polietilenimin Taşıyıcı Sisteminin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)Target-specific delivery of small interfering siRNAs in cancer treatment is one of today's leading research topics. Within the scope of the thesis, effective transport of siRNAs via hyaluronic acid (HA) receptor was carried ... -
KANSER TEDAVİSİNDE KULLANILAN RESVERATROLÜN İLAÇ TAŞIYICI SİSTEM OLARAK KİTOSAN-ALJİNAT KOMPOZİT BİYOJELLERE YÜKLENMESİ VE SALIMININ İNCELENMESİ
(Fen Bilimleri Enstitüsü, 2018-06-07)In this thesis, Ca - Alginate spheres, Alginate - Chitosan hybrid spheres and resveratrol cross - linked chitosan nanoparticles were synthesized. By using chitosan and alginate biopolymers, biocomposite spheres were ... -
Karaciğer Tümörlerinin Tedavisinde Uygulanacak Y-90 Mikrokürelerin Aktivite Miktarlarının Hastaya Özgü Modelleme İle Belirlenmesi İçin Yöntem Geliştirilmesi ve Yöntemin Standardize Edilmesi
(Fen Bilimleri Enstitüsü, 2019)Yttrium-90 (Y-90) microsphere treatment is the internal radionuclide treatment through administration of Y-90 loaded microspheres to the tumor microcirculation via the relevant branch of the hepatic artery feeding the ... -
Kemik Çimentolarında Yumurta Kabuğu Zarı Proteininin Kullanımı
(Fen Bilimleri Enstitüsü, 2019-10-07)Within the scope of the presented thesis, it is thought that protein doped bone cements promise potential in terms of biodegradability and strength. Therefore, by adding protein to calcium sulphate based bone cements (CSC), ... -
Kemik Doku Implant Malzemeleri: Osseointegrasyon ve Antibakteriyel Etkinlik
(Fen Bilimleri Enstitüsü, 2015)This study aims to improve antibacterial titanium coating which enhanced osseointegration at the same time. Titanium (Ti) substrates covered with antibacterial polyethylene oxide (PEO) fibers which have functionalized with ... -
Kişiye Özel Kraniyal İmplantlarda Yapısal Parametrelerin Araştırılması: Sonlu Elemanlar Analizi Uygulaması
(Fen Bilimleri Enstitüsü, 2020)Cranioplasty is a surgical procedure for repairing skull defects. These defects can be caused by congenital defects, diseases, accidents, infections or tumors. Cranioplasty, ensuring the integrity of the skull, not only ... -
Kişiye Özel Temporamandibular Eklem Protezinin Tasarlanması ve Katmanlı İmalat Teknolojisi ile Üretimi
(Fen Bilimleri Enstitüsü, 2019-10-22)The Temporomandibular Joint (TMJ) is a small joint located at the junction of the skull and the lower jaw in front of the ear. It provides movement and function of the lower jaw (mandible). Any damage (usually trauma, ... -
Kitosan Nanopartiküllerine Ve Kitosan-Halloysit Nanokompozitlerine Metronidazole Yüklenmesi, Salınımı Ve Adsorpsiyonunun İncelenmesi
(Fen Bilimleri Enstitüsü, 2017)In this thesis study, it was aimed to obtain the drug carrier and adsorbent material with superior properties than the two components by making the nanoparticles of chitosan nanocomposite by using ionic gelation technique ... -
Kolajen/Beta-Trikalsiyum Fosfat Bazlı Sentetik Kemik Greftlerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2015)Millions of patients worldwide need bone injury treatments due to traffic accidents, sports injuries, daily injuries or genetic diseases. While originating traumas are fixated with appropriate implants, they are also ... -
Kolon Kanser Hücreleri İçin Altın Kaplı Manyetik Yüklü Transfeksiyon Ajanlarının Kullanılması
(Fen Bilimleri Enstitüsü, 2014)Cancer is still one of the most important problems of mankind s health that cause to death. There is a significant portion of spendings in the health sector. The early diagnosis and treatment of cancer and the budgets spent ... -
Kütle Spektrometrisi Uygulamalarında Fosfopeptitlerin Hassas Tayini İçin Yeni Stratejilerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018)Most of the proteins may at some time be phosphorylated on serine, threonine or tyrosine aminoacids when they perform a certain function. Phosphoprotein is protein that contain phosphate group in structure. The smaller ... -
Bir Lokal Anestezik Madde Olan Lidokain'in (2-Dıethylamıno-N-(2,6 Dımethylphenyl) Acetamıde) Etki Süresini Uzatmak için Poli Akrilat Bazlı Hidrojel Mikrokürelerin Kullanımı ve Denenmesi
(Fen Bilimleri Enstitüsü, 2013)Local anaesthetics are used in many space, especially surgial operation in small areas. However, their effect time is short, they need to be repeated continuously and this may cause toxicity that results in many problems. ... -
Manyetik Silika Bazlı Borat Afinite Kromatografisi Sorbentlerinin Sentezi Ve Kromatografik Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2018-06)In this study, β-nicotinamide adenine dinucleotide (β-NAD) was molecularly imprinted onto plain and magnetic silica microspheres in the monodisperse-porous form, by core-shell polymerization method. For this purpose, ... -
MANYETİK VE MANYETİK OLMAYAN SİLİKA BAZLI SABİT FAZLAR KULLANAN DNA MİKROEKSTRAKSİYON SİSTEMLERİNİN GELİŞTİRİLMESİ
(Fen Bilimleri Enstitüsü, 2017)Monodisperse-porous silica microspheres and their magnetic form were synthesized by a newly developed” staged shape templated hydrolysis and condensation protocol”. The human genomic DNA isolation capacity from whole blood ... -
Meme Kanseri Hücreleriyle Üç Boyutlu Tümör Modellerinin Geliştirilmesi ve Noç Reseptörü İnhibitörünün Uygulanması
(Fen Bilimleri Enstitüsü, 2019-06-28)Tissue cultures as disease models are indispensable research tools in the preclinical studies. Two-dimensional (2D) culture that composed in the monolayer form cannot bear the extracellular interactions of the natural ... -
MEME KANSERİ HÜCRELERİNE mTOR ANTİSENS OLİGONÜKLEOTİTLERİNİ HEDEFLEYECEK TRANSFERRİN KAPLANMIŞ ALTIN NANOPARTİKÜLLERİN TASARIMI SENTEZİ VE UYGULANMASI
(Fen Bilimleri Enstitüsü, 2017-10)Breast cancer is the most frequent cancer in women. The type and molecular characteristics of breast cancer determines prognosis and helps design effective therapy regimes. mTOR, the mammalian target of Rapamycin is one ... -
Mezenkimal Kök Hücrelerin Osteojenik Farklılaşmasının Bor Katkılı Hap-Kaplı Kitosan Doku İskelelerinde İncelenmesi
(Fen Bilimleri Enstitüsü, 2015)The aim of the present study is to investigate in-vitro osteogenic potential of mesenchymal stem cells, isolated from two different sources (bone marrow and adipose tissue), on boron doped hydroxyapatite (HAp) coated ... -
Mikrobiyal Hava Toplayıcı ve Okuyucu Sistemi Tasarımı ve Prototip Üretimi
(Fen Bilimleri Enstitüsü, 2015)The detection of air purifier or air pollution is very important step to take necessary precautions to prevent infections. Nowadays, partical measuring and passive air sampling methods are widely used to detect air pollution ... -
Mikrodalga Desteği İle Metakrilatlanmış Kappa Carrageenan Hidrojellerin 3B Baskılanması ve Kıkırdak Doku Mühendisliğinde Kullanımının Araştırılması
(Fen Bilimleri Enstitüsü, 2019)This “3D Bioprinting of Microwave Assisted Methacrylated Kappa Carrageenan Hydrogels and Investigation of Their Usage in Cartilage Tissue Engineering” entitled study was supported by the The Scientific and Technological ...