Dil "en" Temel Tıp Bilimleri Bölümü Tez Koleksiyonu için listeleme
Toplam kayıt 27, listelenen: 1-20
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Analysis Of Oxysterol Species In Type 1 And Type 2 Diabetes Mellitus By Lc-ms/ms Method
(Sağlık Bilimleri Enstitüsü, 2018-12-23)Oxidative stress plays an important role in the pathophysiology of diabetes mellitus (DM). Oxysterols, which resulted from spontaneous or enzymatic oxidation of cholesterol, are potentially non-invasive biomarkers of ... -
Analysıs of The Prevalence, Trends, Determınants and Dynamıcs of Contraceptıve Use and Estımate of Unmet Need For Famıly Plannıng in Pakıstan
(Sağlık Bilimleri Enstitüsü, 2018-09-12)AHMED, F. Analysis of the Prevalence, Trends, Determinants and Dynamics of Contraceptive Use and Estimate of Unmet Need for Family Planning in Pakistan. Hacettepe Unıversity, Graduate School of Health Sciences, Epidemiology ... -
Binary Classification via GMDH-Type Neural Network Algorithm
(Sağlık Bilimleri Enstitüsü, 2018)Group Method of Data Handling (GMDH) - type neural network algorithms are the self organizing algorithms for modeling complex systems. GMDH algorithms are used for different objectives; examples include regression, ... -
Blood Supply of Inferior Turbinate and Lateral Nasal Wall
(Sağlık Bilimleri Enstitüsü, 2017)The blood supply of the nasal cavity acquires a great deal of interest for many reasons; the first, for the treatment of the common condition which is the epistaxis that need some times surgical interventions. The second, ... -
Calculatıon of Choroıdal Vascularıty Index and Tıssue Dıstrıbutıon Indexes by Dıgıtal Processıng of Retınal and Choroıdal Images Obtaıned Vıa Optıcal Coherence Tomography
(Sağlık Bilimleri Enstitüsü, 2018-07-25)Optical coherence tomography is, also called as an optical biopsy, is a valuable tool, and used in many clinical and research areas, including the leading area of ophthalmology. 50 randomly chosen healthy cases, 25 females ... -
Cloning and Determination of Tissue Specific Expression Pattern of Astacus Leptodactylus Na+ Ca 2+ Exchanger Gene
(Sağlık Bilimleri Enstitüsü, 2014)Cytosolic Ca2+ plays an essential role in various cellular functions. Changes in cytosolic Ca2+ concentration is important for different cellular activities like muscle contraction and neurotransmitter release. A set of ... -
CLONING OF Astacus leptodactylus RYANODINE RECEPTOR GENE
(Sağlık Bilimleri Enstitüsü, 2022)Cytoplasmic Ca2+ concentration plays an essential role in many types of cellular function including electro-mechanical coupling in striated muscle fibers. Ryanodine receptor channels (RyR), mediating Ca2+ release from ... -
Cloning Putative Voltage-Gated Calcium Channel Gene in Astacus Leptodactylus and Determination of Structural and Functional Properties of Related Protein
(Sağlık Bilimleri Enstitüsü, 2023)Voltage-gated calcium channels are essential elements in development of many cellular processes like electrical signaling, contraction secretion and gene expression. There has been a fair amount of information about the ... -
COMPARATIVE INVESTIGATION OF EVENT-RELATED POTENTIALS ELICITED BY THE STROOP EFFECT AND EVENT-RELATED POTENTIALS ELICITED BY COLOR CONFLICT
(Sağlık Bilimleri Enstitüsü, 2019)Main interest of cognitive and experimental psychology is the human behavior system. Cognitive control is the key aspect of this system and investigating its neural mechanisms is an important objective method in such ... -
Determination of Lipid Metabolism Alterations and Their Association with Disease Pathogenesis in Sickle Cell Disease
(Sağlık Bilimleri Enstitüsü, 2020-07-07)Sickle cell disease (SCD) is a hemoglobinopathy that causes severe anemia and is characterized by lipid abnormalities, oxidative stress and chronic inflammation. It is caused by a single point-mutation in the beta globin ... -
Development and Application of Novel Machine Learning Approaches for Rna-Seq Data Classification
(Sağlık Bilimleri Enstitüsü, 2015)RNA-Seq is a recent and efficient technique that uses the capabilities of next-generation sequencing technology in characterizing and quantifying transcriptomes. This technique has revolutionized the gene-expression profiling ... -
Examination of İnfant Mortality Risk in Turkey With Spatio-Temporal Bayesian Models
(Sağlık Bilimleri Enstitüsü, 2020)In this thesis, it was aimed to determine relative risk (RR) of infant mortality for each province in Turkey between 2009 and 2017 years by including the concepts of space, time and space-time interaction, to obtain risk ... -
Factors Affecting the Diagnostic Performance of Time-Dependent ROC Curves for Longitudinal Data
(Sağlık Bilimleri Enstitüsü, 2018-07-12)In medicine, ROC Curve Analysis is frequently used to determine the diagnostic performances of biomarkers. However, time-dependent ROC Curve is utilized in assessing the diagnostic accuracies of longitudinal biomarkers. ... -
Improvement of Germ Stem Cell Pool by Leptin Supplementation and Gene Editing for Male Infertility
(Sağlık Bilimleri Enstitüsü, 2020-06-12)Infertility affects up to 12-15% of sexually active couples, and male factors contribute about 30-55% of these cases. Infertility can be caused by injuries, genetic factors, exposure to toxicants, immune-suppressive and ... -
Intern Doctors’ Likelihood of Speakıng Up For Patient Safety
(Sağlık Bilimleri Enstitüsü, 2019-09)Communication breakdowns make significant contributions to medical errors and adverse events in health care. Speak up about patient safety creates a safe atmosphere which is vital to keeping patients safe, preventing errors, ... -
Investigating the Effects of Neurometabolic Disease-Causing Genes on Synapse Function in Drosophila melanogaster
(Sağlık Bilimleri Enstitüsü, 2022)Our group has identified several patients that harbor mutations in genes that hold the potential for being important players of synapse function, UNC79 and MBOAT7 being two of them. UNC79 is one of the accessory ... -
Investigation of the Role of LAP1B in Transcriptional Regulation of Muscle Cells
(Sağlık Bilimleri Enstitüsü, 2021-01-20)The loss-of-function of the inner nuclear membrane protein LAP1B (lamina-associated polypeptide 1, isoform B) causes muscular dystrophy and cardiomyopathy in humans. The function of LAP1B in muscle is still unknown. The ... -
Investıgatıon of The In Vıtro And In Vıvo Effects of Telomere-Targeted New Drug Candıdate Compounds on Dıfferent Cancer Cell Lınes
(Sağlık Bilimleri Enstitüsü, 2023)Cancer, characterized by its heterogeneity, metastatic character, and limited treatability, stands as a leading global cause of mortality. Cancer cells elongate their telomeres through the activity of the telomerase enzyme, ... -
Knowledge Regardıng Infectıon and Preventıon Modes of Hepatıtıs B Dısease and Assocıated Factors Among Fırst Class Students of Nyala Unıversıty in Sudan
(Sağlık Bilimleri Enstitüsü, 2018-10-11)ABSTRACT ELRASHEED, S.I.A., Knowledge Regarding Infection and Prevention Modes of Hepatitis B Disease and Associated Factors Among First Class Students of Nyala University in Sudan. Hacettepe University, Graduate School ... -
Molecular Propertıes of Crayfısh Potassıum Channels
(Sağlık Bilimleri Enstitüsü, 2021)Ergin, B., Molecular Properties of Crayfish Potassium Channels. Hacettepe University Graduate School of Health Sciences, Ph.D. Thesis in Biophysics, Ankara, 2021. Potassium channel family is the largest group in the ion ...