Temel Tıp Bilimleri Bölümü Makale Koleksiyonu: Güncel gönderi
Toplam kayıt 459, listelenen: 41-60
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Clinical Long-Time Course, Novel Mutations And Genotype-Phenotype Correlation In A Cohort Of 27 Families With Pomt1-Related Disorders
(2019)Background The protein O-mannosyltransferase 1, encoded by the POMT1 gene, is a key enzyme in the glycosylation of α-dystroglycan. POMT1–related disorders belong to the group of dystroglycanopathies characterized by a ... -
Class I Histone Deacetylase Inhibition By Aryl Butenoic Acid Derivatives: In Silico And In Vitro Studies
(2019)Histone deacetylases (HDAC) are evolutionary conserved enzymes, which catalyze removal of acetyl groups from histone and non-histone proteins, therefore, control multiple biological processes. Inhibition of their activities ... -
Investigations Of Microtubule-Associated Protein 2 Gene Expression In Spinal Muscular Atrophy
(2019)Aim: Spinal muscular atrophy (SMA) is a devastating genetic disease in childhood andff is caused by the absence of functional survival motor neuron (SMN) protein, which leads to impairments of the cytoskeleton, especially ... -
Effect Of Folic Acid On Cisplatin-Induced Ototoxicity: A Functional And Morphological Study
(2019)OBJECTIVES The aim of our study was to investigate the effects of folic acid on cisplatin-induced ototoxicity. MATERIALS and METHODS Thirty Wistar albino rats were divided into five groups. Group I received intraperitoneal ... -
Epidermal Growth Factor Enhances Spinal Fusion: Posterolateral Lumbar Fusion Model On Rats
(2019)Objective The aim of this study was to investigate the effects of human recombinant epidermal growth factor (EGF) on posterolateral lumbar fusion in a rat model. Methods 36 male Sprague Dawley rats underwent posterolateral ... -
Outcome Of 102 Patients Under 5 Years Of Age With Hodgkin Lymphoma
(2019)Background. Hodgkin's lymphoma (HL) is one of the most curable pediatric cancers, however it is rare among children under five years of age and prognostic factors for survival rate are still unknown due to low frequency ... -
Effects Of Propranolol And Paclitaxel On Angiogenesis In Breast Cancer Cell Lines
(2019)Purpose: The aim of this study was to investigate the effect of propranolol (PR), which is used in infantile hemangiomas, and paclitaxel (PX), which is widely used as an chemotherapeutic agent, on cancer cells. Materials ... -
Effects Of Clozapine And Haloperidol Treatment On Plasma Concentrations Of Androgen Hormones And Androgendependent Organ Changes In Rats
(2019)OBJECTIVES: Metabolic and endocrine adverse effects are among the most concerning unfavorable consequences of commonly used psychotropic drugs. The present research was planned to assess and determine the effects of ... -
The Malignancy Risk Assessment Of Cytologically Indeterminate Thyroid Nodules Improves Markedly By Using A Predictive Model
(2019)Objectives: The majority of thyroid nodules are discovered incidentally, and the management may be a challenge if the fine needle aspiration specimen yields indeterminate findings. Our aim was to develop an individualized ... -
Development, Characterization And Research Of Efficacy On In Vitro Cell Culture Of Glucosamine Carrying Hyaluronic Acid Nanoparticles
(2019)Intra-articular hyaluronic acid (HA) and oral glucosamine (GA) are frequently used to decrease pain and increase function in osteoarthritis patients. Injectable chondroitin sulfate and HA improve effectiveness however a ... -
Pknox2 Expression And Regulation In The Bone Marrow Mesenchymal Stem Cells Of Fanconi Anemia Patients And Healthy Donors
(2019)HOX and TALE transcription factors are important regulators of development and homeostasis in determining cellular identity. Deregulation of this process may drive cancer progression. The aim of this study was to investigate ... -
Changes In Sperm Parameters Following Administration Of Theophylline, A Competitive Antagonist Of Adenosine In Rats Exposed To Bleomycin, A Chemotherapeutic Agent
(2019)The aim of the present study is to determine the effects of theophylline (THP), a methylxanthine derivative, on the sperm parameters of rats exposed to bleomycin (BLM) as a chemotherapeutic agent. The study was performed ... -
Gmdh2: Binary Classification Via Gmdh-Type Neural Network Algorithms-R Package And Web-Based Tool
(2019)Group method of data handling (GMDH)-type neural network algorithms are the self-organizing algorithms for modeling complex systems. GMDH algorithms are used for different objectives; examples include regression, classification, ... -
Effects Of Smoking And Physical Exercise On Respiratory Function Test Results In Students Of University
(2019)We explored the effects of smoking and exercise on pulmonary function (PF) in young adults., This was a 2-year, prospective cross-sectional study on university students. We recorded age, gender, weight, height, pulmonary ... -
Effect Of Hepatosteatosis On The Virological Response In Entecavir And Tenofovir Therapies
(2019)Objective: Both chronic hepatitis B (CHB) and hepatosteatosis may lead to necroinflammation in liver. Therefore, the presence of hepatosteatosis might negatively affect the efficacy of antiviral therapy. We aimed to determine ... -
Factors Affecting The Etiology Of Intractable Pruritus In Hospitalized Patients Without Primary Skin Lesions
(2019)Introduction: Pruritus is a common symptom that has dermatologic, systemic, neurological, psychogenic, mixed, and unknown causes. The aim of this study was to identify the underlying origin of pruritus (UOP) in hospitalized ... -
Cadaveric Anatomy And Dissection In Surgical Training
(2019)Detailed knowledge of anatomy is an essential part of surgical practice. However, there are many drawbacks in anatomy education that make many residents feel inadequate when they start performing surgeries. Cadaveric ... -
An Automated Image Analysis System Can be Beneficial in Preclassification of Leucocytes in Children with Hematological Disease.
(WILEY, 2011)This study was aimed to evaluate the analytical performance of an automated image analysis system (a pilot model of Diff Master™ Octavia) for the preclassification of leucocytes in children with hematological disease. ... -
Twelve Years Of Fluconazole In Clinical Practice: Global-Trends In Species Distribution And Fluconazole Susceptibility Of Bloodstream Isolates Of Candida
(ESCMID, 2004)We determined the species distribution and in-vitro susceptibility of 6082 bloodstream infection (BSI)isolates ofCandidaspp. collected from 250 medical centres in 32 nations over a 10-year period from 1992through 2001. The ...
