Bölüm "Tıbbi Biyokimya" Temel Tıp Bilimleri Bölümü Makale Koleksiyonu için listeleme
Toplam kayıt 44, listelenen: 1-20
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Adamts12 Depletion By Insulin In Oums-27 Human Chondrosarcoma Cells
(Turkish League Against Rheumatism, 2015)Objectives: In this study, we aim to investigate the association between articular damage in diabetes and a disintegrin-like and metalloproteinase with thrombospondin motifs 12 (ADAMTS12) at gene expression and protein ... -
Adamts4 And Adamts5 Knockout Mice Are Protected From Versican But Not Aggrecan Or Brevican Proteolysis During Spinal Cord Injury
(2014)The chondroitin sulfate proteoglycans (CSPGs) aggrecan, versican, and brevican are large aggregating extracellular matrix molecules that inhibit axonal growth of the mature central nervous system (CNS). ADAMTS proteoglycanases, ... -
An Automated Image Analysis System Can be Beneficial in Preclassification of Leucocytes in Children with Hematological Disease.
(WILEY, 2011)This study was aimed to evaluate the analytical performance of an automated image analysis system (a pilot model of Diff Master™ Octavia) for the preclassification of leucocytes in children with hematological disease. ... -
Antiadhesive Effects of Grn163L - An Oligonucleotide N3 '-> P5 ' Thio-Phosphoramidate Targeting Telomerase
(Amer Assoc Cancer Research, 2007)We determined previously that a novel human telomerase RNA (hTR) antagonist, GRN163L, inhibited the tumorigenic potential of A549-luciferase (A549-luc) lung cancer cells in vitro and in vivo. Further studies revealed that ... -
Antioxidant Action of the Antiarrhythmic Drug Mexiletine in Brain Membranes
(Japanese Pharmacological Soc, 1999)Mexiletine is a class Ib antiarrhythmic drug used in the treatment of ventricular arrhythmias. The Naf channel blocker mexiletine inhibits calcium influx in cells via decreasing reverse operation of the Na+-Ca2+ exchanger. ... -
Assessing the Severity of the Small Inframe Deletion Mutation in the Alpha-Subunit of Beta-Hexosaminidase A Found in the Turkish Population By Reproducing It in the More Stable Beta-Subunit
(Springer, 2004)GM(2) gangliosidoses are a group of panethnic lysosomal storage diseases in which GM(2) ganglioside accumulates in the lysosome due to a defect in one of three genes, two of which encode the alpha- or beta-subunits of ... -
Comparison Of Hcmv Ie And Ef-1 Alpha Promoters For The Stable Expression Of Beta-Subunit Of Hexosaminidase In Cho Cell Lines
(Springer/Plenum Publishers, 2006) -
Comparison Of Spectrophotometric And Fluorimetric Methods In Evaluation Of Biotinidase Deficiency
(2016)Background Biotin, a water-soluble vitamin, is used as a co-factor by enzymes involved in carboxylation reactions. Biotinidase (BTD) catalyzes the recycling of biotin from endogenous and dietary sources. Biotinidase ... -
Comparison Of The Effects Of Dexmedetomidine Vs. Ketamine In Cardiac Ischemia/Reperfusion Injury In Rats - Preliminary Study
(Wroclaw Medical Univ, 2014)Objectives. Following ischemia/reperfusion injury, antioxidant defense mechanisms may remain insufficient depending on the duration of ischemia which is caused by any reason (MI, after percutaneous coronary intervention, ... -
Comparison Of The Novel Architect Procalcitonin Assay With Established Procalcitonin Assay Systems
(2018)Aims This study assessed the performance of a new fully automated immunoassay, ARCHITECT B.R.A.H.M.S procalcitonin (PCT), comparing the results with other commercial assays on routine clinical specimens. Methods At nine ... -
Concentrations Of Prealbumin And Some Appetite-Controlling Hormones In Pregnancies Associated With Hyperemesis Gravidarium
(Sage Publications Inc, 2017)Background Hyperemesis gravidarum, which affects 0.3-2.3% of pregnancies, is defined as excessive vomiting during pregnancy and usually starts in week 4 or 5 of gestation. Symptoms include weight loss, dehydration, ketonaemia, ... -
Construction Of Recb-Recd Genetic Fusion And Functional Analysis Of Recbdc Fusion Enzyme In Escherichia Coli
(2008)Background recD, located between recB and argA, encodes the smallest polypeptide (60 kDa) of the heterotrimeric enzyme RecBCD in Escherichia coli. RecD is a 5'-3' helicase and is required for the nuclease activity of RecBCD ... -
Effect of Asiatic Acid on The Treatment of Spinal Cord Injury: an Experimental Study in Rats
(Turkish Neurosurgical Soc, 2017)AIM: Spinal cord injury (SCI) is a devastating condition of the central nervous system. There is no proven therapeutic agent for the treatment of this complex disorder. Asiatic acid (AA) has been used as an anti-inflammatory ... -
Effect of Insulin on The Mrna Expression of Procollagen N-Proteinases in Chondrosarcoma Oums-27 Cells
(Spandidos Publ Ltd, 2015)Chondrosarcoma is one of the most common bone tumors, and at present, there is no non-invasive treatment option for this cancer. The chondrosarcoma OUMS-27 cell line produces proteoglycan and type II, IX, and XI collagens, ... -
Effects Of Clozapine And Haloperidol Treatment On Plasma Concentrations Of Androgen Hormones And Androgendependent Organ Changes In Rats
(2019)OBJECTIVES: Metabolic and endocrine adverse effects are among the most concerning unfavorable consequences of commonly used psychotropic drugs. The present research was planned to assess and determine the effects of ... -
European Views On Patients Directly Obtaining Their Laboratory Test Results
(Walter De Gruyter Gmbh, 2015)Background: Medicine is a highly professionalized endeavour, by tradition centred on the authority of physicians. Better education and the advent of the information age cater for increased demands on society in general and ...