Yayıncı "Amer Assoc Immunologists" Dahili Tıp Bilimleri Bölümü Makale Koleksiyonu için listeleme
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Differential Biological Role Of Cd3 Chains Revealed By Human Immunodeficiencies
(Amer Assoc Immunologists, 2007)The biological role in vivo of the homologous CD3 gamma and delta invariant chains within the human TCR/CD3 complex is a matter of debate, as murine models do not recapitulate human immunodeficiencies. We have characterized, ... -
Human Procaspase-1 Variants With Decreased Enzymatic Activity Are Associated With Febrile Episodes And May Contribute To Inflammation Via Rip2 And Nf-Kb Signaling
(Amer Assoc Immunologists, 2014)The proinflammatory enzyme caspase-1 plays an important role in the innate immune system and is involved in a variety of inflammatory conditions. Rare naturally occurring human variants of the caspase-1 gene (CASP1) lead ... -
Tcr Dynamics in Human Mature T Lymphocytes Lacking Cd3 Gamma
(Amer Assoc Immunologists, 2003)The contribution of CD3gamma to the surface expression, internalization, and intracellular trafficking of the TCR/CD3 complex (TCR) has not been completely defined. However, CD3gamma is believed to be crucial for constitutive ...