İdiyopatik Pulmoner Fibroziste Fonksiyonel Egzersiz Kapasitesi, Periferik Kas Kuvveti, Solunum Kas Enduransı ve Yaşam Kalitesine Etki Eden Parametrelerin Belirlenmesi

Abstract

Göre B., Determination of Parameters Effecting Functional Exercise Capacity, Peripheral Muscle Strength, Respiratory Muscle Endurance and Quality of Life in Idiopathic Pulmonary Fibrosis, Hacettepe University, Graduate School of Health Sciences, Cardiopulmonary Rehabilitation Program, Master Thesis, Ankara, 2025. Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by increased fibrotic tissue in the lungs. The aim of this study was to compare respiratory functions, respiratory muscle strength, respiratory muscle endurance, functional exercise capacity, peripheral muscle strength, functional performance, and physical activity levels between patients with IPF and healthy controls, investigate the relationship between functional exercise capacity of patients with IPF and respiratory functions, respiratory muscle strength, respiratory muscle endurance, peripheral muscle strength, dyspnea, kinesiophobia, cough severity and quality of life. A total of 24 individuals were included in the study, 12 individuals diagnosed with IPF and 12 healthy individuals. Respiratory function test by spirometry, respiratory muscle strength by intraoral pressure measuring device, respiratory muscle endurance by inspiratory muscle training device, functional capacity by 6-minute walking test and 6-minute pegboard and ring test, handgrip strength by hand dynamometer, quadriceps femoris (QF) muscle strength by digital muscle strength test device, functional performance by 30-second sit-to-stand test, physical activity level by Bouchard's 3-Day Physical Activity Record of all particiants and carbon monoxide diffusion capacity by single breath method, dyspnea by Modified Medical Research Council Dyspnea Scale, quality of life by St. George Respiratory Questionnaire, cough severity by Leicester Cough Questionnaire, kinesiophobia by Tampa Scale of Kinesiophobia were evaluated and disease severity was determined by the GAP(gender, age, physiology) index and composite physiological index of patients with IPF. It was found that FVC, FEV1, MEP, functional exercise capacity, QF muscle strength and functional performance of patients with IPF were decreased compared to healthy controls (p<0.05). It was found that functional exercise capacity of patients with IPF was associated with FVC, FEV1, MEP, QF muscle strength, hand grip strength, dyspnea and kinesiophobia (p<0.05). We recommend that functional exercise capacity, respiratory functions, peripheral muscle strength and symptoms be kept in mind when planning rehabilitation programs and that the effectiveness of appropriate exercise programs that include these parameters be evaluated in future studies.