Browsing Kök Hücre Araştırma ve Uygulama Merkezi (PEDISTEM) Makale Koleksiyonu by Subject "HSPCs"

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Enhancement of Mouse Hematopoietic Stem/Progenitor Cell Function Via Transient Gene Delivery Using Integration-Deficient Lentiviral Vectors

Alonso-Ferrero, Maria E.; van Til, Niek P.; Bartolovic, Kerol; Mata, Márcia F.; Wagemaker, Gerard; Moulding, Dale; Williams, David A.; Kinnon, Christine; Waddington, Simon N.; Milsom, Michael D.; Howe, Steven J. (Elsevier Science Bv, 2018)

Integration-deficient lentiviruses (IdLVs) deliver genes effectively to tissues but are lost rapidly from dividing cells. This property can be harnessed to express transgenes transiently to manipulate cell biology. Here, ...