Bölüm "Kök Hücre" Kök Hücre Araştırma ve Uygulama Merkezi (PEDISTEM) için listeleme
Toplam kayıt 11, listelenen: 1-11
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Assessment of the Effects Of Melatonın on the Functıonal Defıcıts Induced by Cellular Stress in Obese Donor Derıved Mesenchymal Stem Cells
(Sağlık Bilimleri Enstitüsü, 2024-06-11)Obesity negatively affects different types of stem cells and BM-MSCs from individuals with a high BMI display a severely impaired differentiation capacity, reduced proliferation and increased ER stress. However, the role ... -
Effects of Syzygium Aromaticum, Cinnamomum Zeylanicum, and Salvia Triloba Extracts on Proliferation and Differentiation of Dental Pulp Stem Cells
(Scielo, 2017)INTRODUCTION: Hypersensitivity, local irritative and cytotoxic effects are known for the chemical components of Syzygium aromaticum and Cinnamomum zeylanicum contained in dental materials. However, there is no intimate ... -
Enhancement of Mouse Hematopoietic Stem/Progenitor Cell Function Via Transient Gene Delivery Using Integration-Deficient Lentiviral Vectors
(Elsevier Science Bv, 2018)Integration-deficient lentiviruses (IdLVs) deliver genes effectively to tissues but are lost rapidly from dividing cells. This property can be harnessed to express transgenes transiently to manipulate cell biology. Here, ... -
Evaluation Of Biocompatibility Of Random Or Aligned Electrospun Polyhydroxybutyrate Scaffolds Combined With Human Mesenchymal Stem Cells
(Tubitak Scientific & Technical Research Council Turkey, 2016)Polyhydroxybutyrate (PHB) is a polymer used to restore tissues or regenerate bones. However, its compatibility with human bone marrow-derived mesenchymal stem cells (MSCs) has not been examined. PHB membranes of random ... -
Expansion Of Human Umbilical Cord Blood Hematopoietic Progenitors With Cord Vein Pericytes
(Tubitak Scientific & Technical Research Council Turkey, 2017)The vascular niche is a site rich in blood vessels, whereas endothelial cells, pericytes, and smooth muscle cells create a microenvironment that recruits mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs), ... -
Hfe H63D Mutation Frequency Shows An Increase In Turkish Women With Breast Cancer
(BioMed Central, 2006)Background The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between cancer and HFE hetero- or homozygosity has previously been shown including hepatocellular and nonhepatocellular ... -
Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Immune and Lysosomal Enzyme Deficiencies
(CyberLeninka, 2016)Rare diseases affect millions of people worldwide. Many of those are inherited disorders resulting in chronic disability and requiring cost-intensive care. Hematopoietic stem cell gene therapy has been developed over more ... -
Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Metabolic Disorders
(Mary Ann Liebert, Inc, 2014)After more than 20 years of development, lentiviral hematopoietic stem cell gene therapy has entered the stage of initial clinical implementation for immune deficiencies and storage disorders. This brief review summarizes ... -
Preclinical Efficacy and Safety Evaluation of Hematopoietic Stem Cell Gene Therapy in a Mouse Model of Mngie
(Elsevier, 2018)Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) is an autosomal recessive disorder caused by thymidine phosphorylase (TP) deficiency resulting in systemic accumulation of thymidine (d-Thd) and deoxyuridine ... -
The Potential For Chemical Mixtures From The Environment To Enable The Cancer Hallmark Of Sustained Proliferative Signalling
(Oxford Univ Press, 2015)The aim of this work is to review current knowledge relating the established cancer hallmark, sustained cell proliferation to the existence of chemicals present as low dose mixtures in the environment. Normal cell proliferation ... -
Thymbra Spicata Var. Intricata Induces Mesenchymal Stem Cell Proliferation and Osteogenic Differentiation
(Inst Tecnologia Parana, 2017)A natural agent that maintains mesenchymal stem cell (MSCs) viability, promotes osteogenic differentiation while modulating the immunological response could achieve success in regeneration during healing and may also prevent ...
