Temel Eczacılık Bilimleri Bölümü: Güncel gönderi
Toplam kayıt 194, listelenen: 21-40
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Glioblastoma Multiforme, Menenjiyom (Birincil) ve Metastaz (İkincil) Beyin Tümörlerine Ait Fenotiplerin Belirlenmesinde Kullanılacak Bütünleşik Omiks Analizler İçin Analitik Yöntem Geliştirilmesi ve Uygulanması
(Sağlık Bilimleri Enstitüsü, 2022)A thorough examination of intermediate molecular levels such as protein, metabolite, and lipid is required to establish direct causal and functional links between genotype and phenotype. Comprehensive metabolomics and ... -
Kolon Kanserinin Tedavisinde Fenotiyazin Yapılı Bileşiklerin Kullanımlarının Değerlendirilmesi ve Etki Mekanizmalarının Araştırılması
(Sağlık Bilimleri Enstitüsü, 2022-07). Epidemiological studies associate cancer and neurodegenerative diseases with each other. Amyloid precursor protein (APP), which is closely related to Alzheimer's disease, attracts attention in cancer research. Recent ... -
Alkole Bağlı Olmayan Karaciğer Yağlanması Tedavisinde Nano-Enkapsüle İlaçların Etkinliğinin Lc/Q-Tof Ms ile Gerçekleştirilen Metabolomik ve Lipidomik Çalışmalarla İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)In this thesis, the efficacy of vitamin E loaded nanoparticles developed using Human Serum Albumin (ISA) nanoparticles in the treatment of non-alcoholic fatty liver disease (NAFLD) was investigated by LC/Q-TOF MS-based ... -
Sezyum-137’nin İnsan Sağlığı Üzerindeki Etkilerinin Toksikolojik Açıdan Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)Cesium-137, a radioactive isotope of cesium, is an element that emits beta and gamma radiation and has a half-life of 30 years. It is important to determine the effects of this element on human health, especially ... -
İşle İlişkili Astım ve Silikozis Tanılı Hastalarda Oksidatif Stres Parametrelerinin ve Genotoksik Etkilerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)Asthma is a global health problem that affects more than 300 million people in the world. About 10-33% of adult-onset asthma is work-related asthma (WRA). Silicosis is an occupational lung disease that can result in the ... -
Nanoteknolojinin Farmasötik Uygulamalarda Kullanımının ve Nanopartiküllerin Toksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021-12)ACAR, E. H., Evaluation of the Use of Nanotechnology in Pharmaceutical Applications and the Toxic Effects of Nanoparticles, Hacettepe University Graduate School Health Sciences Pharmacy Department of Pharmaceutical Toxicology ... -
Sülfür Metabolizmasında Yer Alan Metabolitlerin Miktar Tayini için LC-MS/MS Yönteminin Geliştirilmesi ve Valide Edilmesi
(Sağlık Bilimleri Enstitüsü, 2021-08)Sulfur metabolites play critical roles in cellular function. Changes in the levels and metabolism of sulfur compounds, were associated with cancer, which have led to the need to make precise, accurate and fast determination ... -
Farmasötik Kimya 2
(Hacettepe Üniversitesi Yayınları, 2016)Bu kitap, son yıllarda farmasötik kimya alanında gözlenen hızlı ve sürekli gelişmeleri aktaran Türkçe bir kaynak olarak hazırlanmıştır. Kitabın ilk üç baskısının akademik ve eczacılık çevrelerinde gördüğü ilgi nedeniyle ... -
Farmasötik Kimya 1
(Hacettepe Üniversitesi Yayınları, 2016)Bu kitap, son yıllarda farmasötik kimya alanında gözlenen hızlı ve sürekli gelişmeleri aktaran Türkçe bir kaynak olarak hazırlanmıştır. Kitabın ilk üç baskısının akademik ve eczacılık çevrelerinde gördüğü ilgi nedeniyle ... -
Indian Saffron - Turmeric (Curcuma Longa) Embedded Supermacroporous Cryogel Discs For Heavy Metal Removal
(2019)Cryogels are used in a variety of environmental and biotechnological processes. Cryogels are polymeric materials with large pores and open flow channels. Turmeric is a very popular spice, especially in India, which has ... -
Effects Of Timolol Treatment On Pancreatic Antioxidant Enzymes In Streptozotocin-Induced Diabetic Rats: An Experimental And Computational Study
(2019)Background: The study aimed to investigate whether timolol-treatment has a beneficial effect on pentose phosphate pathway enzyme activities such as glucose-6-phosphate dehydrogenase (G6PD), 6-phosphogluconate dehydrogenase ... -
Altered Hdl Particle In Sickle Cell Disease: Decreased Cholesterol Content Is Associated With Hemolysis, Whereas Decreased Apolipoprotein A1 Is Linked To Inflammation
(2019)Background Hypocholesterolemia is the most frequently encountered lipid abnormality in sickle cell disease (SCD). We enrolled pediatric patients to determine the relationships between lipid profile and parameters of ... -
Data The Dehp Induced Changes On The Trace Element And Mineral Levels In The Brain And Testis Tissues Of Rats
(2019)Di (2-ethylhexyl) phthalate (DEHP) is used as plasticizer in the industry and belongs to the phthalate family which can induce tissue damage including kidney, liver, and testis as a result of elevated oxidative stress ... -
Correction To: Evaluation Of Hydrocar Efficiency For Simultaneous Removal Of Diclofenac And Ibuprofen From Aqueous System Using Surface Response Methodology (Environmental Science And Pollution Research, (2019), 10.1007/S11356-019-04359-Z)
(2019)The original publication of this paper contain typographical mistakes. The published paper had missed letter ‘H’ in some parts of text, references and figure captions. These changes does not affect the findings of paper. ... -
The Effect Of Effort Test On The Levels Of Ischemia Modified Albumin, 7-Ketocholesterol And Cholestan-3Β , 5Α , 6Β -Triol And Their Role In The Diagnosis Of Coronary Artery Disease
(2019)Background Oxysterols have been shown to play a role in plaque formation while ischemia modified albumin (IMA) is widely accepted as an acute marker for ischemia. The effort test is one of the methods used to identify the ... -
Long-Term Effects Of Early-Life Antibiotic Exposure On Resistance To Subsequent Bacterial Infection
(2019)The gastrointestinal microbiota protects hosts from enteric infections; while antibiotics, by altering the microbiota, may diminish this protection. We show that after early-life exposure to antibiotics host susceptibility ... -
Islamic Fasting Leads To An Increased Abundance Of Akkermansia Muciniphila And Bacteroides Fragilis Group: A Preliminary Study On Intermittent Fasting
(2019)Background/Aims It has been largely accepted that dietary habits affect intestinal microbiota composition. In this pilot study, we hypothesized that time-restricted feeding, which can be regarded as a type of intermittent ...
