Eczacılık Teknolojisi Bölümü: Recent submissions
Now showing items 61-80 of 99
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Few Drugs Display Flip-Flop Pharmacokinetics And These Are Primarily Associated With Classes 3 And 4 Of The Bddcs
(Wiley, 2015)This study was conducted to determine the number of drugs exhibiting flip-flop pharmacokinetics following oral (p.o.) dosing from immediate-release dosage forms and if they exhibit a common characteristic that may be ... -
Effects Of Transforming Growth Factor-Beta-1 Neutralizing Antibody And Transforming Growth Factor-Beta-3 On The Development Of Tracheal Stenosis
(Baycinar Medical Publ-Baycinar Tibbi Yayincilik, 2017)Background: This study aims to evaluate the effects of transforming growth factor-beta 3 and neutralizing antibody of transforming growth factor-beta 1 containing polymeric polycaprolactone film formulations on prevention ... -
Effect of Topically Applied Sildenafil Citrate on Wound Healing: Experimental Study
(Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2014)Wound healing is a complex process that necessitates organization of different cell types and several signalling molecules. The aim of this study is to evaluate the effect of different concentrations of sildenafil citrate, ... -
Estimation Of Aqueous Distributional Spaces In The Dual Perfused Rat Liver
(Cambridge Univ Press, 2000)1. The aim of this study was to estimate the aqueous distributional spaces of the liver as a function of the route of input: portal vein (PV) versus hepatic artery (HA). 2. Studies were performed in the in situ single (PV) ... -
Development of Polycationic Amphiphilic Cyclodextrin Nanoparticles for Anticancer Drug Delivery
(2017)Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum of cancers. To overcome its bioavailability problems arising from very poor aqueous solubility and tendency to recrystallize upon ... -
Drug Delivery Systems for Imaging And Therapy of Parkinson'S Disease
(2016)Background: Although a variety of therapeutic approaches are available for the treatment of Parkinson’s disease, challenges limit effective therapy. Among these challenges are delivery of drugs through the blood brain ... -
Effect of Locally Applied Transforming Growth Factor Beta3 on Wound Healing and Stenosis Development in Tracheal Surgery
(Daedalus Enterprises Inc, 2014)BACKGROUND: Tracheal stenosis constitutes one of the most frequently seen problems in thoracic surgery. Although many treatment modalities to prevent fibroblast proliferation, angiogenesis, or inflammation that causes ... -
Development Of Novel Self-Assembled Polymeric Micelles From Partially Hydrolysed Poly(2-Ethyl-2-Oxazoline)-Co-Pei-B-Pcl Block Copolymer As Non-Viral Vectors For Plasmid Dna In Vitro Transfection
(Taylor & Francis Ltd, 2018)A new efficient, non-viral gene delivery cationic polymeric micellar system was developed by partial hydrolysis of poly(2-ethyl-2-oxazoline) (PEtOx) with two different hydrolysis percentages of PEtOx (30% and 60%) to reduce ... -
Development Of A Peptide-Containing Chewing Gum As A Sustained Release Antiplaque Antimicrobial Delivery System
(Springer, 2007)The objective of this study was to characterize the stability of KSL-W, an antimicrobial decapeptide shown to inhibit the growth of oral bacterial strains associated with caries development and plaque formation, and its ... -
18Th European Symposium On Radiopharmacy And Radiopharmaceuticals
(2016)OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets, V. Radchenko, J.W. Engle, C. Roy, J. Griswold, M.F. Nortier, E.R. Birnbaum, M. Brugh, S. Mirzadeh, K. D. John, M.E. ... -
Stabilite ve Reaksiyon Kinetiği
(Hacettepe Üniversitesi, 2009)Ülkemizde Türkçe ders kitabı sayısının çok sınırlı olması ve hatta bazı konularda hiç kitap olmaması önemli bir eksikliktir. Öğrencilere ders teksiri verilmesi veya öğrencilerin derslerde not tutmaları yerine, çeşitli ... -
Parental Preparatlar Teknolojisi
(Hacettepe Üniversitesi, 2009)Sanayileşme olgusunun en çok değişime uğrattığı mesleklerden biri kuşkusuz eczacılık ve özellikle Farmasötik Teknoloji konulandır. Buna rağmen, ülkemizde yayımlanmış Türkçe ders kitabı sayısının çok sınırlı olmasının büyük ... -
Doksorubisin ve elakridar içeren PLGA/silika hibrit nanopartiküllerin formülasyonu ve meme kanserindeki etkinliğinin değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Although doxorubicin is efficient alone in cancer treatment, its being a substrate of P-glycoprotein (P-gp) limits its effectiveness. Various approaches have been developed to overcome the growing resistance to these drugs. ... -
Ağızda Dağılan Tablet Formülasyonlarının In Vitro Karakterizasyonları ve Permeabiliteleri Üzerine Farklı Yardımcı Maddelerin ve Basım Tekniklerinin Etkisi
(Sağlık Bilimleri Enstitüsü, 2019)Orally disintegrating tablets are easier and safer to administered in pediatric and geriatrics, patients with difficulty in swallowing and neurological diseases compared with conventional tablets. Orally disintegrating ... -
Küçük Hücreli Dışı Akciğer Kanser Hücrelerine Hedeflendirilmiş Kombine İlaç İçeren Teranostik Lipozomların Etkinliğinin İzlenmesi
(Sağlık Bilimleri Enstitüsü, 2019-08)Overall, cancer is a fundamental health issue all around the world. In particular, lung cancer is the type that has the highest incidence and mortality rate. Although several methods including chest x-rays, computed ... -
Hedeflendirilmiş Antikanser İlaç Yüklü Polimerik Nanotaşıyıcıların Formülasyonları ve Karakterizasyonları
(Sağlık Bilimleri Enstitüsü, 2019)The distribution of the drugs used in cancer chemotherapy without distinction between the diseased area and the healthy area causes damage to healthy tissue. By using targeted drug delivery systems it is intended to ... -
Karbenoksolon Disodyum İçeren Nanopartikül Formülasyonlarının Tasarımı ve Kortikal Yayılan Depresyona Bağlı Migren Tedavisindeki Etkinliğinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Recent studies on migraine, one of the most common diseases among neurological diseases, have shown that cortical spreading depolarization waves, cause transient opening of Pannexin-1 mega channels from neuronal cell ... -
Development of Nano-Formulatıons Contaınıng Neuroprotectıve Actıve Ingredıent and Evaluatıon of Effıcıency in Perıpheral Nerve Injury Model
(Sağlık Bilimleri Enstitüsü, 2018-11-13)HAIDAR Mohammad Karim, Development of Nano-formulations Containing Neuroprotective Active Ingredient and Evaluation of Efficiency in Peripheral Nerve Injury Model, Hacettepe University Graduate School of Health Sciences, ...