Eczacılık Meslek Bilimleri Bölümü: Recent submissions
Now showing items 41-60 of 348
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Yenidoğan Hastalarda İlaç Kaynaklı Sorunlar
(Sağlık Bilimleri Enstitüsü, 2022-11-01)The higher rate of drug-related problems (DRPs) in hospitalized neonates is associated with the diversity of prescribed drugs and differences in age, weight and diagnosis. The aims of this study were (i) to perform risk ... -
Bazı Gentianella Türlerinin Fitokimyasal Analizleri ve Sekonder Metabolitlerinin BDNF (Beyin-Türevli Nörotrofik Faktör) Üzerindeki Etkileri
(Sağlık Bilimleri Enstitüsü, 2022)Gentianella Moench (Gentianaceae) species contain many secondary metabolites such as xanthones, flavonoids and terpenes. Flavonoids have been reported to contribute to the antidepressant effects of many medicinal plants ... -
The Role and Importance of Dorsal And Ventral Hıppocampal Catecholamınergıc Innervatıons in Socıal Memory of Rats
(Sağlık Bilimleri Enstitüsü, 2022)This study aims to investigate the role and importance of the catecholaminergic innervations in the dorsal (DH) and ventral hippocampus (VH) in social memory of rats. Female Wistar rats were injected bilaterally with ... -
Dihidropiridin Türevlerinin Sentezi ve L-/T-Tipi Kalsiyum Kanal Bloke Edici Aktiviteleri
(Sağlık Bilimleri Enstitüsü, 2022-07-19)1,4- Dihydropyridines (DHPs) are the most well known inhibitors of L-type calcium channels and have important therapeutic value against cardiovascular diseases. Since they target different calcium channel subtypes, they ... -
İmidakloprid ve Asetamipridin İn Vitro Sistemler Üzerindeki Toksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022-06-27)Neonicotinoids, which have received attention in recent years due to their toxic effects on non-target organisms, particularly bees, are a nicotine-derived insecticide group that is widely used in many countries, including ... -
Sistemik Antifungal İlaç Kullanımının Değerlendirilmesi ve Antifungal Yönetim Ekibi Uygulamaları
(Sağlık Bilimleri Enstitüsü, 2022)Implementation of antifungal stewardship (AFS) program aims to reduce inappropriate use of antifungal drugs. The role of AFS program in the appropriate use of antifungal therapy was evaluated in this study. This study was ... -
Aşılarda Kullanılan Koruyucu ve Adjuvan Maddelerin Olası Toksik Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)The World Health Organization defines vaccines as “pharmaceutical products that enable our immune system to recognize and fight pathogens such as viruses and bacteria and protect our body against the diseases caused by ... -
Hekzahidrokinolin Türevlerinin Sentezi, Sitotoksik Özelliklerinin, ROS Oluşturma Potansiyellerinin ve Enflamasyon Mediyatörleri Üzerine Etkilerinin İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2022)In this study, novel 24 compounds with alkyl 2,6,6-trimethyl-4-(disubstituted phenyl)-5-oxo- 1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (Compound 1a-1f, 2a-2f, 3a-3f and 4a-4f) structure which is expected to show ... -
Serviks Kanserinde Timokinon ve Etoposid Kombinasyonunun Hücre Canlılığı Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2022). Cervical cancer is the second most common type of cancer in women, after breast cancer, that causes the death of a woman every two minutes in the world. Major treatment options include surgery, radiotherapy, and ... -
Monoamin Oksidaz İnhibitörü Etki Göstermesi Beklenen Yeni Hidrazon Bileşiklerinin Sentezi, Moleküler Modellemesi ve MAO-A /MAO-B Seçiciliklerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2022-02-11)In this study, 16 compounds were synthesized as 2 compounds (Compound 1 and 2) of N'-substitutedbenzylidene-2-(5-chloro-2-benzoxazolinon-3-yl)acetohydrazide, 6 compounds (Compounds 3-8) of 3-(substituted ... -
1-FENİL-2-(1H-İMİDAZOL-1-İL)ETANON OKSİM ESTERLERİNİN SENTEZİ VE BİYOLOJİK ETKİLERİ ÜZERİNDE ÇALIŞMALAR
(Sağlık Bilimleri Enstitüsü, 2020-02-19)Yurtoglu, S., Studies on Synthesis and Biological Effects of 1-Phenyl-2-(1H-imidazol-1-yl) ethanone oxime esters , Hacettepe University, Institute of Health Sciences, MS Thesis in Pharmaceutical Chemistry, Ankara, 2020. ... -
İnsan Kolostrum Sütünde Neopterin ve Kinürenin Düzeylerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Deliveli, S., Examining the amounts of neopterin and kynurenine in human colostrum milk, Hacettepe University Graduate School of Health Sciences, Pharmaceutical Toxicology Program, Master Thesis, Ankara, 2021. Colostrum ... -
Halk İlacı Olarak Kullanılan Peganum harmala L. (Üzerlik) Tohumları Üzerinde İlaç Hammaddesi Yönünden Araştırmalar
(Sağlık Bilimleri Enstitüsü, 2022)Peganum harmala L., which is the only species representing the genus Peganum in Turkey, is known as “üzerlik” and is widely used as folk medicine. It is known that pharmacological studies performed on the plant support ... -
Genisteinin Dna Hasarı Üzerindeki Etkilerinin Kolon Kanseri Hücrelerinde Tek Hücre Jel Elektroforez (Comet) Yöntemiyle Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Çal Doğan, T., Evaluation of The Effects of Genistein on DNA Damage by Single Cell Gel Electrophoresis (Comet) in Colon Cancer Cells, Hacettepe University Institute of Health Sciences Doctor of Philosophy Thesis on ... -
Akrilamid ve 5-Hidroksimetilfurfural'in Olası Genotoksik Etkilerinin Tek Hücre Jel Elektroforez Yöntemi ile İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)The cooking processes of foods containing carbohydrates forms acrylamide and 5-hydroxymethylfurfural (HMF) as a result of Maillard reaction. According to previous in vivo and in vitro tests, these two substances ... -
Türkiye’de Faaliyet Gösteren İlaç Firmalarının Kurumsal Sosyal Sorumluluk Projelerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021-09-23)Corporate Social Responsibility (CSR) is defined as companies voluntarily taking an active role with their own resources in solving social, economic and environmental problems of the society wherein they operate and ... -
Bazı Yeni Tiyazolo[3,2-b]-1,2,4-triazol-6(5H)-on Türevlerinin Sentezi ve Sitotoksik Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021-07-13)In this study, thirty new hybrid chalcone derivatives, namely 2- substituted-5-benzylidentiazolo[3,2-b]-1,2,4-triazol-6(5H)-one (4a-6j) which is expected to show cytotoxic activity were synthesized. Titled compounds were ... -
Bazı Lamiaceae Familyası Bitkilerinin Osteoartrite Karşı Etkilerinin Matriks Metalloproteinaz-3 (Mmp-3) İnhibitör Etki Tayini ile Tespiti
(Sağlık Bilimleri Enstitüsü, 2021)Tahravi, L., Characterization of the Effects of Some Lamiaceae Family Plants Against Osteoarthritis by Matrix Metalloproteinase-3 (MMP-3) Inhibitory Effect Determination, Hacettepe University, Graduate School of Health ... -
Erken Adölesan ve Adölesan Dönemde Ftalat Maruziyetinin Epigenetik Mekanizmalar ve Metabolik Profil Üzerindeki Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2021-07-08)Di (2-ethyl hexyl) phthalate (DEHP) is a chemical that has endocrine disrupting properties and is widely used in many customer products. Studies on DEHP show that toxicity specifically targets the male reproductive system. ... -
Neopterin Düzeylerinin ve Kinürenin Yolağının Akut Koroner Sendrom Hastalarında Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Kember, İ. Evaluation of Neopterin Levels and Kynurenine Pathway in Acute Coronary Syndrome Patients. Hacettepe University Graduate School of Health Sciences Pharmaceutical Toxicology Program PhD Thesis, Ankara, 2021. The ...
