Erişim Hakları "Attribution 4.0 United States" Eczacılık Meslek Bilimleri Bölümü için listeleme
Toplam kayıt 29, listelenen: 1-20
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A New Generation Of Dihydropyridine Calcium Channel Blockers: Photostabilization Of Liquid Formulations Using Nonionic Surfactants
(2019)The stability profile of a new 1,4-dihydropyridine derivative (DHP), representative of a series with a hexahydroquinoline ring, was studied to design light-stable liquid formulations. This molecule, named M3, has been shown ... -
A New Perspective On Evaluation Of Medicinal Plant Biological Activities: The Correlation Between Phytomics And Matrix Metalloproteinases Activities Of Some Medicinal Plants
(2019)Phytomics or metabolomics is analysis of large-scale primary and secondary metabolites of plant extracts and provides very meaningful data to monitor or evaluate cellular function or systems biology. The activity of plant ... -
Acetylcholinesterase Inhibitory Activities And Lc-Ms Analysis Of The Antioxidant Ferula Caspica M. Bieb. And F. Halophila Pesmen Extracts
(2019)The aim of the current study is to evaluate the biological activity of F. caspica M. Bieb. which is used for the treatment of diabetes in traditional Turkish medicine and to compare with F. halophila Pesmen. Antioxidant ... -
Alpha-Pyrone Glycosides From Scutellaria Salviifolia Benth
(2019)Scutellaria salviifolia Benth. is an endemic species growing in Turkey that belongs to the family Lamiaceae. As a result of a phytochemical study on the aerial parts of S. salviifolia Benth., two new and 10 known compounds ... -
An Exploratory Study Of Neopterin And Kynurenine Pathway In Pterygium
(2019)Pterygium is an inflammatory, vascular and degenerative disorder with unknown aetiology. The aim of this study was to evaluate the changes in neopterin levels, reflecting T-cell immunity, and the kynurenine pathway, the ... -
An In Vitro Study On The Cytotoxicity And Genotoxicity Of Silver Sulfide Quantum Dots Coated With Meso-2,3-Dimercaptosuccinic Acid
(2019)Objectives: Silver sulfide (Ag2S) quantum dots (QDs) are highly promising nanomaterials in bioimaging systems due to their high activities for both imaging and drug/gene delivery. There is insufficient research on the ... -
Antimicrobial Activity Of Three Scutellaria L. Species From Turkey
(2019)Plant-sourced antimicrobials are known for their therapeutic potency against multi-drug-resistant pathogens. The members of Scutellaria L. have been used to cure several diseases in East Asia, Europe, and North America. ... -
Antioxidants And Selenocompounds Inhibit 3,5-Dimethylaminophenol Toxicity To Human Urothelial Cells
(2019)Exposure to alkyl anilines may lead to bladder cancer, which is the second most frequent cancer of the urogenital tract. 3,5-dimethylaniline is highly used in industry. Studies on its primary' metabolite 3,5-dimethylaminophenol ... -
Bioactivity-Guided Isolation Of Anti-Inflammatory Principles From Cistus Parviflorus Lam.
(2019)Bioactivity-guided fractionation and purification of Cistus parvillorus led to the isolation of two flavan-3-ol derivatives; gallocatechin (1) and epigallocatechin (2) and two flavonoid glycosides; avicularin (3) and ... -
Bmprii Deficiency Impairs Apoptosis Via The Bmprii-Alk1-Bclx-Mediated Pathway In Pulmonary Arterial Hypertension
(2019)Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disorder characterized by the remodelling of pre-capillary pulmonary arteries. The vascular remodelling observed in PAH patients results from excessive ... -
Capecitabine Induced Hand-Foot Syndrome: A Systematic Review Of Case Reports
(2019)Objective: Capecitabine, a prodrug of 5-fluorouracil, is currently used in the treatment of metastatic colorectal and breast cancers. The aim of this study was to review the pharmacological mechanisms, treatment strategies, ... -
Direct Enantiomeric Resolution Of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives By Hplc
(2019)1,4-Dihydropyridine (DHP) scaffold holds an outstanding position with its versatile pharmacological properties among all heterocyclic compounds. Although most of the commercially available DHPs are marketed as a racemic ... -
Discovery And Characterisation Of Dual Inhibitors Of Tryptophan 2,3-Dioxygenase (Tdo2) And Indoleamine 2,3-Dioxygenase 1 (Ido1) Using Virtual Screening
(2019)Cancers express tryptophan catabolising enzymes indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO2) to produce immunosuppressive tryptophan metabolites that undermine patients’ immune systems, leading ... -
Eczacılık Fakültesi Laboratuvar Çalışma Güvenliği El Kitabı
(Hacettepe Üniversitesi Yayınları, 2017)30.06.2012 tarihinden itibaren uygulamaya ilişkin çok sayıda yönetmelik ve tebliğ yayımlanmıştır. Bunlardan biri olan "Çalışanların İSG Eğitimlerinin Usul ve Esasları Hakkında Yönetmelik" gereğince, "az tehlikeli işyerleri" ... -
Endocannabinoid System In The Airways
(2019)Cannabinoids and the mammalian endocannabinoid system is an important research area of interest and attracted many researchers because of their widespread biological effects. The significant immune-modulatory role of ... -
Epigenetic And Genetic Changes Caused By Helicobacter Pylori And Their Roles In Gastric Carcinogenesis
(2019)Objective: Helicobacter pylori is a bacteria which colonizes in the gastric mucosa and it is one of the major infectious diseases throughout the world. There are findings pointing out that Helicobacter pylori can cause ... -
Evaluation Of Some Biological Effects Of Incarvillea Emodi (Royle Ex Lindl.) Chatterjee And Determination Of Its Active Constituents
(2019)This present study was an evaluation of the antioxidant and cytotoxic activities of Incarvillea emodi (Bignoniaceae). The aqueous extracts of different parts of Incarvillea emodi, collected from different places in Pakistan, ... -
In Vitro Investigation Of The Effects Of Boron Nitride Nanotubes And Curcumin On Dna Damage
(2019)Backround Stem cells provide an opportunity to analyse the effects of xenobiotic on cell viability, differentiation and cell functions. Evaluation of the possible cytotoxic and DNA damaging effects on bone marrow CD34+ ... -
Interactions Of Aromatase And Seladin-1: A Neurosteroidogenic And Gender Perspective
(2019)Aromatase and seladin-1 are enzymes that have major roles in estrogen synthesis and are important in both brain physiology and pathology. Aromatase is the key enzyme that catalyzes estrogen biosynthesis from androgen ... -
Molecular Modeling-Based Delivery System Enhances Everolimus-Induced Apoptosis In Caco-2 Cells
(2019), Several studies have shown that the mammalian target of rapamycin (mTOR) inhibitor; everolimus (EV) improves patient survival in several types of cancer. However, the meaningful efficacy of EV as a single agent for the ...
