Browsing Uygulama ve Araştırma Merkezleri by Title

Now showing items 1-20 of 29

    • Assessment of the Effects Of Melatonın on the Functıonal Defıcıts Induced by Cellular Stress in Obese Donor Derıved Mesenchymal Stem Cells 

      Polat, Ece Gizem (Sağlık Bilimleri Enstitüsü, 2024-06-11)
      Obesity negatively affects different types of stem cells and BM-MSCs from individuals with a high BMI display a severely impaired differentiation capacity, reduced proliferation and increased ER stress. However, the role ...

    • Cardiac Patch Design: Compatibility of Nanofiber Materials Prepared by Electrospinning Method with Stem Cells 

      Celebi Saltik, Betul; Oteyaka, Mustafa Ozgur (Tubitak Scientific & Technical Research Council Turkey, 2016)
      In this article, in order to create a cardiac patch, a biocompatible polyurethane (PU) nanofiber polymer was developed with the electrospinning method. Bone marrow mesenchymal stem cells (BM MSCs) were isolated from whole ...

    • Effects of Syzygium Aromaticum, Cinnamomum Zeylanicum, and Salvia Triloba Extracts on Proliferation and Differentiation of Dental Pulp Stem Cells 

      Mendi, Ayşegül; Yağcı, Beyza Gökçınar; Kızıloğlu, Mustafa; Saraç, Nurdan; Yılmaz, Derviş; Uğur, Aysel; Uçkan, Duygu (Scielo, 2017)
      INTRODUCTION: Hypersensitivity, local irritative and cytotoxic effects are known for the chemical components of Syzygium aromaticum and Cinnamomum zeylanicum contained in dental materials. However, there is no intimate ...

    • Enhancement of Mouse Hematopoietic Stem/Progenitor Cell Function Via Transient Gene Delivery Using Integration-Deficient Lentiviral Vectors 

      Alonso-Ferrero, Maria E.; van Til, Niek P.; Bartolovic, Kerol; Mata, Márcia F.; Wagemaker, Gerard; Moulding, Dale; Williams, David A.; Kinnon, Christine; Waddington, Simon N.; Milsom, Michael D.; Howe, Steven J. (Elsevier Science Bv, 2018)
      Integration-deficient lentiviruses (IdLVs) deliver genes effectively to tissues but are lost rapidly from dividing cells. This property can be harnessed to express transgenes transiently to manipulate cell biology. Here, ...

    • Evaluation Of Biocompatibility Of Random Or Aligned Electrospun Polyhydroxybutyrate Scaffolds Combined With Human Mesenchymal Stem Cells 

      Köse, Sevil; Aerts Kaya, Fatıma; Denkbaş, Emir Baki; Korkusuz, Petek; Çetinkaya, Fahriye Duygu (Tubitak Scientific & Technical Research Council Turkey, 2016)
      Polyhydroxybutyrate (PHB) is a polymer used to restore tissues or regenerate bones. However, its compatibility with human bone marrow-derived mesenchymal stem cells (MSCs) has not been examined. PHB membranes of random ...

    • Expansion Of Human Umbilical Cord Blood Hematopoietic Progenitors With Cord Vein Pericytes 

      Celebi Saltık, Betül; Gökçınar Yağcı, Beyza (Tubitak Scientific & Technical Research Council Turkey, 2017)
      The vascular niche is a site rich in blood vessels, whereas endothelial cells, pericytes, and smooth muscle cells create a microenvironment that recruits mesenchymal stem cells (MSCs) and hematopoietic stem cells (HSCs), ...

    • Gastroscopic Evaluation Of Gastric Ulcer Syndrome In Sport Horses With Poor Performance 

      Çetinkaya, Mehmet Alper; Demirutku, Alper; Kaya, Mahir (Scientific Technical Research Council Turkey-Tubitak, 2013)
      Gastric ulceration is common in performance horses. More than 90% of thoroughbred horses in the training season and approximately 60% of racing horses from other disciplines have gastric ulcers. Excessive secretion of ...

    • Gençlik ve Dijital Çağ 

      Demirci Aksoy, Aybala; Ateş, Emre Cihan; Ateş, Atiye Pınar; Avşar Arık, Işıl; Şahin Kütük, Birsen; Görgün Baran, Aylin; Başdemir, Cansu; Bilgiç, Hatice Gökçe; Seferoğlu, Süleyman Sadi; Çakır, Mehmet; Çelen, Fatma Kübra; Hazer, Oya; Işıklı, Sedat; Kırboğa, Ziyaeddin; Nazik, M. Hamil; Demirel, Hüsne; Bayraktar, Ayşe; Olgun, Cem Koray; Öztürk, Emre; Öztürk, M. Serhat; Yaman, Fatih; Kabakçı Yurdakul, Işıl; Dönmez, Onur; Yeğen, Ceren; Dönmez, S. Can; Yıldız Durak, Hatice; Yılmazel, Sefa Emre (Hacettepe Üniversitesi, 2020)
      Hayatımızın giderek sanal hale gelmeye başladığı dijital çağ devriminin tam ortasında bulunmaktayız. Dijital çağ öncesi dönemde, suç kavramı genel olarak coğrafi alanlarla ilişkilendirilirdi ve suç işlenmesi için fiziksel ...

    • Hepatosit Büyüme Faktörü (Hgf) ile Lisanslanmış Mezenkimal Kök Hücrelerde Anti-Fibrotik mİRNA İfade Düzeyleri 

      Alişan, Ali Berk (Sağlık Bilimleri Enstitüsü, 2024)
      Alişan, AB., Expression Levels Of Anti-Fibrotic miRNA's in Hepatocyte Growth Factor (HGF) Primed Mesenchymal Stem Cells, Hacettepe University Graduate School of Health Sciences Stem Cell Program Master’s Thesis, Ankara, ...

    • Hfe H63D Mutation Frequency Shows An Increase In Turkish Women With Breast Cancer 

      Günel Özcan, Aysen; Alyılmaz Bekmez, Sibel; Güler, Emine Nilüfer; Güç, Dicle (BioMed Central, 2006)
      Background The hereditary hemochromatosis gene HFE plays a pivotal role in iron homeostasis. The association between cancer and HFE hetero- or homozygosity has previously been shown including hepatocellular and nonhepatocellular ...

    • Hypertrophic Osteopathy In A Dog Associated With Intra-Thoracic Lesions: A Case Report And A Review 

      Çetinkaya, Mehmet Alper; Yardımcı, B.; Yardımcı, Cenk (Czech Academy Agricultural Sciences, 2011)
      This paper reviews hypertrophic osteopathy and describes one case report. Hypertrophic osteopathy is a rare pathologic disease process and is observed secondary to a mass in the thorax. In response to the presence of a ...

    • Köpek ve Kedilerde Koksofemoral Eklem Luksasyonlarının Sağaltımında Monofilament Naylon Dikiş Materyali ile Toggle Pin Uygulamaları ve Klinik Değerlendirmeleri Üzerine Çalışmalar 

      Çetinkaya, Mehmet Alper; Olcay, Burhanettin (Ankara Univ Press, 2011)
      Bu çalışmada koksofemoral luksasyonların toggle pin uygulaması ile sağaltımında, monofilament naylon balıkçı misinasının intra-artiküler stabilizasyon amacıyla kullanımının klinik ve radyografik olarak sonuçlarının ...

    • Kültürel Bellek 2016 

      Akpolat, Mustafa S.; Alp, Selda; Altıkulaç Demirdağ, Refika; Çalışkan, Uğur; Çelik Şavk, Ülkü; Ekti, Meltem; İnci, Petek Ersoy; Gelgeç Bakacak, Ayça; Görgün Baran, Aylin; Günay Erkol, Çimen; Gündüz Küskü, Sema; Günel, Gökçe; Zoe Güneş, Ayşin; Gürdaş, Bora; Kocaman, Ahmet; Kolankaya Bostancı, Neyir; C. Koşar, Deniz; Küçük, Serhat; Özkan Koç, Esra; Özkan, Ahmet; Özüm, Aytül; Pultar, Gönül; Barbara Stanek, Kamila; Şahin Kütük, Birsen; Tek, Şinasi; Tosun, Çiler Buket; Tunçer, Mehmet; Türkyılmaz, Çetin; Yasa Yaman, Zeynep; Yenişehirlioğlu, Filiz; Yılmaz, Bülent; Külcü, Özgür; Çakmak, Tolga (Hacettepe Üniversitesi, 2019)

    • Kültürel Bellek 2017 

      Akpolat, Mustafa S.; Gökçe, Ş. Güneş Can; Alp, Selda; Altay, Armağan; Asan, Nuray; Atasoy, Tuğrul; Ayyıldız, Bülent; Can, Özgür Ceren; Cangöz, Banu; Cengizkan, Ali; Çonoğlu, Salim; Ekinci, Pınar; Eren Kaya, Fazile; Ergün Atbaşı, Nurtaç; Erkan, Serdar; Ersoy İnci, Petek; Günay Erkol, Çimen; Karlıdağ, Esra; Kolankaya Bostancı, Neyir; Önder, Alev; Özkan, Ahmet; Özkul Fındık, Nurşen; Öztekin, Özge; Pekak, M. Sacit; Reis, Huriye; Selekler, Kaynak; Sipahioğlu, Z. Sibel; Stanek, Kamila Barbara; Taşpınar, Zerrin; Şahin Tekinalp, Pelin; Tezcan Kaya, Gülsen; Tosun, Buket; Tunçer, Mehmet (Hacettepe Üniversitesi Yayınları, 2021)
      KÜLTÜREL BELLEK 2017 kitabımızda, 7-8-9 Kasım 2017'de üniversitemizin Bilimsel Araştırma Projeleri Koordinasyon Birimi'nin desteğiyle gerçekleştirdiğimiz sempozyumdan seçilmiş yazılar ve konuyla ilgili olduğunu ...

    • Kültürel Mirasın İzinde Ankara 

      Dervişoğlu, Efnan; Doğan, Âbide; Ener Su, Aydan; Ercilasun, Bilge; Garan Gökşen, Bahanur; Gökşen, Erol; Görgün, Baran Aylin; Gürdaş, Bora; Karaca, Nesrin; Kısıklı, Emine; Koşar, Deniz C.; Özdağ, Ufuk; Sakaoğlu, Saim; Sipahioğlu, Zeynep Sibel; Sönmez, Begüm; Sülüner, H. Sinan; Tezcan, Nuran; Tunçer, Mehmet; Üstün, Koray; Çelik, S. Dilek Yalçın; Taşpınar, Zerrin; İnanç, Remzi; Doğan, M. Mahzun; Tekinalp, Pelin Şahin; Demirkan, Eser; Aykurt, Ayşegül; Gökalp Alpaslan, G. Gonca (Hacettepe Üniversitesi Yayınları, 2016)
      Kentlerin belleği vardır. Sokakların, meydanların, binaların, kaldırımların, parkların, taşların ve ağaçların belleği... Cansız bina yığınından ve koşturan insanlardan ibaret gibi görünen kentlerin belleği... Elinizde ...

    • Lactobacillus Rhamnosus Could Inhibit Porphyromonas Gingivalis Derived Cxcl8 Attenuation 

      Mendi, Ayşegül; Köse, Sevil; Uçkan, Duygu; Akca, Gülçin; Yilmaz, Derviş; Aral, Levent; Gültekin, Sibel Elif; Eroğlu, Tamer; Kiliç, Emine; Uçkan, Sina (Scientific Electronic Library Online, 2016)
      An increasing body of evidence suggests that the use of probiotic bacteria is a promising intervention approach for the treatment of inflammatory diseases with a polymicrobial etiology. P. gingivalis has been noted to have ...

    • Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Immune and Lysosomal Enzyme Deficiencies 

      Wagemaker, Gerard (CyberLeninka, 2016)
      Rare diseases affect millions of people worldwide. Many of those are inherited disorders resulting in chronic disability and requiring cost-intensive care. Hematopoietic stem cell gene therapy has been developed over more ...

    • Lentiviral Hematopoietic Stem Cell Gene Therapy in Inherited Metabolic Disorders 

      Wagemaker, Gerard (Mary Ann Liebert, Inc, 2014)
      After more than 20 years of development, lentiviral hematopoietic stem cell gene therapy has entered the stage of initial clinical implementation for immune deficiencies and storage disorders. This brief review summarizes ...

    • N-Acetylglucoseamine Modified Alginate Sponges As Scaffolds For Skin Tissue Engineering 

      Demirbilek, Murat; Türkoğlu Laçin, Melisa; Aktürk, Selçuk (Tubitak Scientific & Technical Research Council Turkey, 2017)
      In the treatment of dermal wounds, wound-dressing materials prepared from natural mucopolysaccharides are widely used because of their advantages such as nonirritation, nontoxicity, and ease in topical application. In the ...

    • Optimization Of A-Si: H/C-Si Heterojunction Solar Cells By Numerical Simulation 

      Bilgiç Aksari, Melis; Eray, Aynur (Elsevier Science Bv, 2011)
      In this study design and optimization of a-S:H/c-Si heterojunction solar cell was done with AFORS-HET simulation program. Detailed simulation studies of I-V characterization of solar cells have been carried out with TCO/(n) ...