Eczacılık Meslek Bilimleri Bölümü Makale Koleksiyonu: Güncel gönderi
Toplam kayıt 189, listelenen: 21-40
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Direct Enantiomeric Resolution Of Seventeen Racemic 1,4-Dihydropyridine-Based Hexahydroquinoline Derivatives By Hplc
(2019)1,4-Dihydropyridine (DHP) scaffold holds an outstanding position with its versatile pharmacological properties among all heterocyclic compounds. Although most of the commercially available DHPs are marketed as a racemic ... -
Antimicrobial Activity Of Three Scutellaria L. Species From Turkey
(2019)Plant-sourced antimicrobials are known for their therapeutic potency against multi-drug-resistant pathogens. The members of Scutellaria L. have been used to cure several diseases in East Asia, Europe, and North America. ... -
The Evaluation Of Sterile Solutions Of Ilwensisaponin A And C From Verbascum Pterocalycinum Var. Mutense Hub.-Mor. On Antiviral, Antinociceptive And Anti-Inflammatory Activities
(2019)Antiviral, antinociceptive and anti-inflammatory activities of the 1% sterile solutions of Ilwensisaponin A and C isolated from the methanolic extract of the flowers of Verbascum pterocalycinum var. mutense Hub.-Mor. were ... -
The Inhibitory Effects Of Isolated Constituents From Plantago Major Subsp. Major L. On Collagenase, Elastase And Hyaluronidase Enzymes: Potential Wound Healer
(2020)Plantago major L. which is a medicinal plant with important biological activities, commonly used as traditional medicine. Potential inhibitory activities of the aqueous extract and three isolated constituents calceorioside ... -
The Effect Of Quercus Coccifera L. Extract On The Necrosis Of Random-Pattern Skin Flaps In Rats
(2019)Aim: Ischemia-reperfusion injury is an important cause of flap loss. We investigated effects of Quercus coccifera L. extract known to have anti-oxidant and anti-inflammatory activity on skin flap viability. Methods: Eighteen ... -
Interactions Of Aromatase And Seladin-1: A Neurosteroidogenic And Gender Perspective
(2019)Aromatase and seladin-1 are enzymes that have major roles in estrogen synthesis and are important in both brain physiology and pathology. Aromatase is the key enzyme that catalyzes estrogen biosynthesis from androgen ... -
Endocannabinoid System In The Airways
(2019)Cannabinoids and the mammalian endocannabinoid system is an important research area of interest and attracted many researchers because of their widespread biological effects. The significant immune-modulatory role of ... -
Bioactivity-Guided Isolation Of Anti-Inflammatory Principles From Cistus Parviflorus Lam.
(2019)Bioactivity-guided fractionation and purification of Cistus parvillorus led to the isolation of two flavan-3-ol derivatives; gallocatechin (1) and epigallocatechin (2) and two flavonoid glycosides; avicularin (3) and ... -
Evaluation of Oxidative and Antioxidative Parameters in Pediatric Hematopoietic SCT Patients
(Springer Nature, 2012)Conditioning regimens preceding hematopoietic SCT (HSCT) usually consist of high-dose chemotherapy. Chemotherapy and radiation therapy are associated with increased formation of free radicals and depletion of critical ... -
Assessment Of Genotoxic Effects Of Pendimethalin In Chinese Hamster Over Cells By The Single Cell Gel Electrophoresis (Comet) Assay
(Turkish Pharmacists Association, 2017)Objectives: Pendimethalin (N-(1-ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzeneamine) is a dinitroaniline herbicide compound which selectively controls weeds. It is a cell division and growth inhibitor. It descends plants in ... -
Microwave-Assisted Synthesis Of Condensed 1,4-Dihydropyridines As Potential Calcium Channel Modulators
(Scientific Technical Research Council Turkey-Tubitak, 2015)This study reports the design, synthesis, and calcium channel modulatory activity evaluation of a series of 14 novel fused 1,4-dihydropyridine derivatives. The molecular design of the compounds was based on modifications ... -
Low Doses Of Selenium Specifically Stimulate The Repair Of Oxidative Dna Damage In Lncap Prostate Cancer Cells
(Informa Healthcare, 2012)Epidemiological studies have demonstrated an inverse relationship between selenium (Se) intake and cancer incidence and/or mortality. However, the molecular mechanisms underlying the cancer chemopreventive activity of Se ... -
Lycopene Restores Trace Element Levels in Ochratoxin A-Treated Rats
(Inst Medical Research & Occupational Health, 2017)This study was designed to investigate the in vivo effects of ochratoxin A (OTA) and/or lycopene on the levels of selenium, zinc, and copper in the liver, kidneys, and testes of male Sprague-Dawley rats. The rats were ... -
Luddin Type Anthraquinone Glycosides from Putoria Calabrica
(Pharmaceutical Soc Japan, 2002)Two new lucidin type anthraquinone glycosides, putorinoside A (1) and putorinoside B (2) were isolated from Putoria calabrica, in addition to two known anthraquinone glycosides, lucidin 3-O-beta-glucopyranoside (3) and ... -
Isolation And Structure Elucidation Of Uncommon Secondary Metabolites From Cistus Salviifolius L.
(Acg Publications, 2015)To our knowledge this is the first report on the isolation of a flavonoid glycoside: quercetin 3-O-alpha-arabinopyranoside (5), two phenylbutanon glycosides: 4-(4'-O-[6''-O-galloyl-beta-galactopyranosyl]-3'-hydroxyphenyl ... -
Low Dose Simvastatin Induces Compositional, Structural and Dynamic Changes in Rat Skeletal Extensor Digitorum Longus Muscle Tissue
(Portland Press Ltd, 2010)Statins are commonly used drugs in the treatment of hypercholesterolaemia. There are many adverse effects of statins on skeletal muscle, but the underlying mechanisms remain unclear. In the present study, the effects of ... -
Leadership and Healthcare Services
(Intech Europe, 2017)The reasons why organizations make changes in various fields, especially in their structure, include various changing situations such as globalization, increasing awareness in human rights and employee rights, developments ...