Erişkin Kistik Fibrozisli ve Sağlıklı Bireylerin Fonksiyonel Kapasite, Yürüme ve Solunum Parametrelerinin Karşılaştırılması

Abstract

Functional capacity, gait and respiratory parameters of individuals with adult cystic fibrosis (CF) may be affected. However, it is not known how much these parameters are affected compared to healthy individuals. The purpose of this study was to compare the functional capacity, gait and breathing parameters of adults with CF and healthy individuals. Twenty three CF individuals and 23 age and gender matched healthy individuals with participated in this study. The physical and demographic characteristics of the subjects were recorded. Lung functions were measured using a spirometer. Forced expiratory volume in one second (FEV1), forced vital capacity (FVC), FEV1/FVC and mid expiratory flow rate (FEF25-75%) values were recorded. Respiratory muscle strength (maximal inspiratory pressure,MIP, maximal expiratory pressure,MEP) was measured using an mouth pressure measuring device. Respiratory muscle endurance at a fixed threshold load (60% of MIP) was evaluated and recorded in seconds. Exercise capacity was evaluated using incremental shuttle walking test (ISWT). Oxygen saturation (SpO2), heart rate (HR), blood pressure, muscle oxygenation (SMO2), dyspnea, quadriceps and general fatigue using modified borg scale were evaluated before and after the test. Gait parameters were evaluated using gait analyzer. Parameters of including gait cycle (seconds), walking speed (m/sec), maximum walking distance (m), stride length (m), step count and ambulation index were recorded for 6 minutes during walking. As a result of the study, lung function of adults with CF were lower than healthy individuals (p<0.05). Between the two groups was no significant difference in MIP and MEP values (p>0.05). Respiratory muscle endurance of individuals with adult CF was lower than healthy individuals (p<0.05). The ISWT, distance, post-test HR and systolic blood pressure, pre-test SpO2, pre-test and post-test SMO2 values were significantly lower in adults with CF compared to healthy individuals (p<0.05). Baseline, HR and dyspnea values were higher in adult CF patients than healthy individuals (p <0.05). The walking speed of adults with CF was lower than that of healthy individuals (p<0.05). There was no significant difference between the two groups in the results of other gait parameters (p>0.05). Respiratory muscle strength of adult CF patients was preserved. Lung function, respiratory muscle endurance, ISWT distance and walking speed were lower in adult CF with healthy individuals. İmpaired respiratory endurance, functional capacity and walking parameters values of adult CF patients should be taken into consideration when planning pulmonary rehabilitation programs. If necessary, appropriate approaches should be included in the program.