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DESIGN AND OPTIMIZATION OF QCM BIOSENSOR TO DETECT MALIGNANT MELANOMA CELLS VIA THEIR CD44 RECEPTORS
(Fen Bilimleri Enstitüsü, 2024)Malignant melanoma (MM) is a highly aggressive form of skin cancer originating from melanocytes, presents a significant public health concern globally. Its rising incidence and propensity for metastasis underscore the ... -
Poli(Etilen-Ard-Maleik Anhidrit)/Poli(Etilen Glikol) Karışımı Temelli Tabakalı Silikat Nanokompozitlerin Hazırlanması ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2024-07-03)ABSTRACT PREPARATION AND CHARACTERIZATION OF POLY(ETHYLENE-ALT-MALEIC ANHYDRIDE)/POLY(ETHYLENE GLYCOL) BLEND BASED LAYERED SILICATE NANOCOMPOSITES Mustafa Levent BOZDAĞ Master of Science, Department of ... -
İyonlaştırıcı Radyasyonun Platinle Kürleştirilmiş Silikon Elastomerlerin Kimyasal ve Fiziksel Özelliklerine Etkisi
(Fen Bilimleri Enstitüsü, 2024)The main purpose of this thesis is to investigate the change in mechanical, dynamic mechanical, and structural properties of platinum-cured VMQ and PVMQ elastomers irradiated with ionizing radiation. Firstly, silicone ... -
BİYOSİDAL ETKİLİ SENTETİK PEPTİTLERİN ETKİNLİĞİNİN VE STABİLİTESİNİN ARTIRILMASI
(Fen Bilimleri Enstitüsü, 2024-07)Antibiotics, which are used intensively against pathogens to protect food, animal, and human health, pose a threat to the environment and human health over time by causing residue, antibiotic resistance, and neurological ... -
Deniz Ürünlerindeki Bazı Eser Türlerin Magnetik Derin Ötektik Çözücüler ile Mikroekstraksiyonu ve Tayini İçin Yeşil Bir Yöntem Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2024)The aim of this thesis is to determine trace amounts of crystal violet (CV) and cadmium (Cd(II)) in water samples and seafood, and to develop a magnetic deep eutectic solvent-based dispersive liquid-liquid microextraction ... -
Trombin Saflaştırılması İçin Moleküler Baskılanmış Mikrokriyojeller
(Fen Bilimleri Enstitüsü, 2024)The field of protein purification appears as a very necessary method to understand the structural and functional properties of proteins and to explain their roles in cells and tissues. Nowadays, with the developments in ... -
Covid-19 Tedavisi İçin Rna-Bağımlı Rna Polimeraz(RDRP) İnhibitörlerinin Sanal Ligand Taraması Yöntemiyle Tasarlanması
(Fen Bilimleri Enstitüsü, 2024)The COVID-19 pandemic, which started in December 2019 in Wuhan, China, has since become a global outbreak. Consequently, the virus that causes COVID-19 has been named SARS-CoV-2. According to data from the World Health ... -
Manyetik Mikromotorların Hazırlanması ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2024)Micro/nanomotors are systems that can convert energy into motion and have been developed as a result of different synthesis chemistry approaches. Synthesizing functional materials with movement properties has paved the way ... -
Çekirdek/Kabuk Yapısına Sahip Silika Jel İçerisine Piren İçeren Amfifilik Polimerlerin Enkapsülasyonu ve Sensör Uygulamaları
(Fen Bilimleri Enstitüsü, 2024)In recent years, there has been great interest in the development of fast and reliable chemical sensors to detect trace amounts of hazardous chemicals. These sensors have potential applications in environmental cleanup ... -
İlaç Taşıyıcı Olarak Halloysit İçeren Nanosüngerlerin Tasarımı, Sentezi ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2024)Nanomaterials are of significant importance in many industries today due to their special properties and usage areas. Due to their small size and high surface area-to volume ratios, nanomaterials exhibit unique characteristics. ... -
Hg2+ ve Cu2+ İyonlarının Tayini İçin Kemosensör Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2024-07-03)In this study, it was aimed to synthesise a new chemosensor for the determination of metal ions in water samples. Especially for the determination of Hg2+ ions, which show toxic effects even at low concentrations, synthesis ... -
Kardiyak Miyozin Bağlayıcı Protein-C Tayini için Optik Temelli Sensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2024-06)Cardiac myosin binding protein-C (cMyBP-C) plays a critical role in the contraction of cardiac muscle, and dysfunctions in this protein can lead to severe cardiovascular diseases. This thesis addresses the limitations of ... -
Mitomycin C Release from Molecularly Imprinted Microcryogels
(Fen Bilimleri Enstitüsü, 2022-04-04)Molecularly imprinted polymers (MIPs) offer the self-organization of functional monomer/s around target molecules, leading formation of area for the target molecules with the high selectivity. Here, microscale cryogels as ... -
Şarj Edilebilir Li-İyon Piller İçin Karbon Esaslı Li2CuP2O7 Katot Elektrotlarının Geliştirilmesi ve Elektrokimyasal Performanslarının İncelenmesi
(Fen Bilimleri Enstitüsü, 2024)Lithium-ion batteries are widely used in various fields, from the healthcare sector to the defense industry, transportation, and communication, and their demand is constantly increasing. Among the primary objectives of ... -
Mikro-, Nano- Demir Hidroksiapatit Özkompozitinin Sentezi, Karakterizasyonu ve Atık Sudaki Katalitik Aktivitesinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2024)In this master of science thesis study, metal doped/undoped hydroxyapatites in various size were blended in determined ratio to synthesize its self-composites. Iron doped/undoped hydroxyapatite self-composites synthesized ... -
Amin ve Fenollerin Tespitine Yönelik BOPHY ve BODIPY Tabanlı Bileşiklerin Sentezi
(Fen Bilimleri Enstitüsü, 2024)Determination of amines and phenols is highly important for the environment and human health. Contamination in wastewater and spoilage in food products can be identified by the detection of these compounds. The design ... -
Bal Analizlerinde GC-MS Temelli Metabolomik Metot ve Uygulamaların Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2024)Honey is accepted as an energy-providing food and an important medicine in many countries of the world due to its functional properties and nutritional values. Honey is also known for its biological, physiological and ... -
Poli (2-Hidroksietil Metakrilat) Aşılanmış Manyetik FE203 Nanoparçacıkların Sentezi ve Kontrollü Doksorubisin Salım Uygulaması
(Fen Bilimleri Enstitüsü, 2024)The development of drug delivery systems is one of the most critical and challenging areas in modern medicine. Effective and targeted drug delivery can enhance treatment efficacy and reduce undesirable side effects, making ... -
Amfifilik Polimer Tabanlı Tablet Katalizör Sistemleri: Π-Π İstiflenmesi ile Altın-NHC Komplekslerini İçeren Yeni Nesil Nano-Reaktörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2024)The hydrophobic nature of organometallic catalysts used in organic reactions in aqueous environment limits their use, while the complexes used in the reactions are sensitive to moisture and water, making reactions difficult. ... -
Moleküler Modelleme Yöntemleri ile Organik Yarı İletkenlerin Bant Aralıklarının İncelenmesi ve Bilgisayar Destekli İlaç Tasarımı
(Fen Bilimleri Enstitüsü, 2023)Molecular modeling is all the theoretical and computerized methods used to model, study or simulate the behavior of molecular systems. These methods are mainly used to provide theoretical predictions for a molecular system, ...
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