Browsing Tıp Fakültesi by Funding "TÜBİTAK"
Now showing items 1-17 of 17
-
Anoreksiya Nervoza Olan Kız Ergenlerde Beden İmgesinin Fonksiyonel Manyetik Rezonans Görüntüleme ile Çalışılması
(Tıp Fakültesi, 2021)Anorexia Nervosa (AN) is a psychiatric disorder characterized by restriction of food intake despite very low body weight and body image disturbance. We aimed to clarify body image disorder in this study by using functional ... -
Cloning Putative Voltage-Gated Calcium Channel Gene in Astacus Leptodactylus and Determination of Structural and Functional Properties of Related Protein
(Sağlık Bilimleri Enstitüsü, 2023)Voltage-gated calcium channels are essential elements in development of many cellular processes like electrical signaling, contraction secretion and gene expression. There has been a fair amount of information about the ... -
Çocuklarda Çoklu Sistemik İnflamatuvar Sendrom (MIS-C) Tanı ve Takibinde Elastin Türevi Peptidlerin Kullanımı ve Tayini İçin Yeni Bir Yarışmalı İndirekt ELISA Protokolü Geliştirilmesi
(Tıp Fakültesi, 2024-05)Multisystem Inflammatory Syndrome in Children (MIS-C) is a hyperinflammatory syndrome involving multiple organs, particularly striking cardiac involvement following SARS-CoV-2 infection. Diagnosis of MIS-C relies on clinical ... -
Desminin çekirdeğe taşınımının potansiyel mekanizmalarının araştırılması
(Sağlık Bilimleri Enstitüsü, 2024)Kural Mangıt E., Investigation of Potential Mechanisms for Nuclear Transport of Desmin. Hacettepe University, Graduate School of Health Sciences, Ph.D. Thesis in Medical Biology, Ankara, 2024. Studies have shown that ... -
Düşük Kas Kütlesi ve Kemik Mineral Yoğunluğunun Akut İskemik İnme Sonlanımına Etkileri
(Tıp Fakültesi, 2022-04-05)Due to the neurologic damage caused, acute ischemic stroke is considered to be amongst the most important causes of disability and loss of work power both in our country and in the World. The disability caused by ischemic ... -
Fare Melanom Tümör Modelinde Radyoterapide Kullanılan Farklı Doz Hızlarının Tümör Mikroçevresi Üzerine Etkileri
(Tıp Fakültesi, 2022)The dose rate is an important variable that affects cell survival. With the introduction of modern accelerators and treatment techniques with high dose rate capacity, it has become important in external radiotherapy (RT) ... -
Geoepidemiology and clinical characteristics of neonatal lupus erythematosus: a systematic literature review of individual patients’ data
(TÜBİTAK, 2020-01-09)Background/aim: Neonatal lupus erythematosus (NLE) is an autoimmune syndrome caused by transplacental transmission of maternal autoantibodies, often with devastating consequences. The objective of this systematic literature ... -
Glukozilseramidaz-Beta Gen Mutasyonlarının Dopaminerjik Nöronlarda α-sinüklein Yıkım Mekanizmaları Üzerindeki Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Glucosylceramidase-Beta (GBA1) Gene Mutations are the most important risk factor identified for Parkinson's Disease (PD). Clinically, 'mild' GBA1 mutations (such as N370S) associated with non-neuropathic Gaucher Disease ... -
Investigation of the Role of LAP1B in Transcriptional Regulation of Muscle Cells
(Sağlık Bilimleri Enstitüsü, 2021-01-20)The loss-of-function of the inner nuclear membrane protein LAP1B (lamina-associated polypeptide 1, isoform B) causes muscular dystrophy and cardiomyopathy in humans. The function of LAP1B in muscle is still unknown. The ... -
Karakterize Edilemeyen Kalıtsal Kemik İliği Yetmezliklerinde Genetik Nedenlerin Araştırılması
(Tıp Fakültesi, 2022)Inherited Bone Marrow Failure Syndromes (IBMFSs) are a heterogeneous group of disorders that result from deficiency of in a single or more hemapoetic cell lineages. Fanconi Anemia, Dyskeratosis Congenita, Shwachman Diamond ... -
Mekanosensitif İyon Kanalı Adayı Genlerin Astacus Leptodactylus Türünde Klonlanması ve İlgili Proteinlerin Fonksiyonel ve Yapısal Özelliklerinin Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2024-07-10)Cells respond to various mechanical stimuli like tension or osmotic pressure changes in the membrane. Mechanosensitive ion channels play an important role in mechanotransduction, which is the conversion of mechanical stimuli ... -
Molecular Propertıes of Crayfısh Potassıum Channels
(Sağlık Bilimleri Enstitüsü, 2021)Ergin, B., Molecular Properties of Crayfish Potassium Channels. Hacettepe University Graduate School of Health Sciences, Ph.D. Thesis in Biophysics, Ankara, 2021. Potassium channel family is the largest group in the ion ... -
Mycobacterium Tuberculosis Klinik İzolatlarında Yeni Antitüberküloz İlaçlar Olan Bedaquiline ve Delamanid'in MİK Değerlerinin ve Dirence Neden Olan Mutasyonların Saptanması
(Sağlık Bilimleri Enstitüsü, 2020)The purpose of this study is to detect the minimum inhibitory concentration (MIC) values of these novel drugs against to 101 resistant-M.tuberculosis clinical isolates with MGIT 960 automatized liquid culture system ... -
Periferik Sinir Defekt Onarımında Biyolojik Kondüit Modeli: De-Epitelize İnsan Amniyotik Membranı ve Adipoz Kökenli Mezenkimal Kök Hücre Tabakası İçeren Sinir Kondüit Modelinin Sinir İyileşmesine Etkisinin Değerlendirilmesi
(Tıp Fakültesi, 2020)Although the first choice for reconstruction of nerve defects in peripheral nerve injuries is autologous nerve graft, new searches continue due to the fact that it requires functional nerve sacrification, severe donor site ... -
Preferences of inflammatory arthritis patients for biological disease-modifying antirheumatic drugs in the first 100 days of covid-19 pandemic
(Turk J Med Sci, 2021-02-22)To evaluate treatment adherence and predictors of drug discontinuation among patients with inflammatory arthritis receiving bDMARDs within the first 100 days after the announcement of COVID-19 pandemic. Method: A total of ... -
The Investıgatıon of Mechanoregulatory Role of Desmın
(Sağlık Bilimleri Enstitüsü, 2024)Desmin, a muscle-specific protein, shapes the network of intermediate filaments (IFs) in different types of muscles, such as cardiac, skeletal, and smooth muscles. Recent studies have elucidated cytoskeletal proteins' ... -
Yenilikçi Bir Smad Bildirici Yaklaşımı Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2024-01)Transforming growth factor-β (TGF-β) is a signaling molecule that has a regulatory role in many physiological processes such as cell differentiation, apoptosis, and regulation of immune response, especially wound healing. ...
