Bölüm "Biyokimya" Tıp Fakültesi için listeleme
Toplam kayıt 11, listelenen: 1-11
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Analysis Of Oxysterol Species In Type 1 And Type 2 Diabetes Mellitus By Lc-ms/ms Method
(Sağlık Bilimleri Enstitüsü, 2018-12-23)Oxidative stress plays an important role in the pathophysiology of diabetes mellitus (DM). Oxysterols, which resulted from spontaneous or enzymatic oxidation of cholesterol, are potentially non-invasive biomarkers of ... -
Anne ve Kordon Kanında Organoklorin Pestisit Düzeylerinin Belirlenerek Annenin Biyokimyasal Parametreleri ve Yenidoğan Üzerindeki Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2017)Due to their environmental and biological long half-lives, it is known that banned organochlorine pesticides are still present in every corner of the world and human exposure persists. In this study, determination of ... -
Bisfenol A’nın Hepg2 Hücrelerine Olan Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Öz, E. Examination of the Effects of Bisphenol A on HepG2 Cells. Hacettepe University Graduate School of Health Sciences, Biochemistry Program, Master Thesis, Ankara, 2020. In this study, it was aimed to determine the ... -
Bisfenol A’nın SH-SY5Y Nöroblastoma Hücrelerindeki Asetilkolinesteraz Gen Ekspresyonuna Olan Etkilerinin Nitrik Oksit Sentaz Aracılığıyla İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017)In this study, SH-SY5Y human neuroblastoma cells treated with low doses of Bisphenol A (BPA). Bisphenol A is a commonly used endocrine disruptor. The cytotoxicity of BPA to SH-SY5Y cells was determined by MTT and LDH assays, ... -
Doksorubisinin Luminal A ve Üçlü Negatif Meme Kanseri Hücrelerinde p53 Apoptoz Yolağı ve Çoklu İlaç Direnci Üzerinde Farklı Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017-11-23)Breast cancer is the most common diagnosed cancer type amongst women. Although it is known that cell signaling pathways such as apoptosis, necrosis, and regulation cell cycle are known to be influental on breast cancer ... -
Faktör XII'nin retinal vasküler ödem üzerine etkisi
(Sağlık Bilimleri Enstitüsü, 2017)Kallikrein-kinin system(KKS) is a known mediator of vasogenic edema in patients with retinal vascular diseases. Although its effects are well characterized on vascular permeability and retinal thickness, the initiator of ... -
Fenilketonüride Öğrenme Bellek Mekanizmasının Dişi Ve Erkek Sıçanlarda cAMP/PKA/CREB/BDNF Yolağı Üzerinden İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2020)Phenylketonuria is a rare hereditary metabolic disease characterized by deficiency of phenylalanine hydroxylase. The absence of enzyme causes blood phenylalanine levels to rise. If patients are not treated, irreversible ... -
Kolestaz Hastalarında Safra Asitlerinin Lc-Ms/Ms ile Araştırılması ve Olası Biyobelirteçlerin Belirlenmesi
(Sağlık Bilimleri Enstitüsü, 2020-02-18)Inborn errors of bile acid synthesis (IEBAS) are autosomal recessively inherited disorders that are resulted from the deficiencies in the structure or function of the enzymes involved in the synthesis of bile acids, causing ... -
Serebral İskemi Modelinde Oluşan Nöroinflamasyon Üzerine 12/15 Lipooksijenaz İnhibitörlerinin Etkisi
(Sağlık Bilimleri Enstitüsü, 2018)In this study, our aim was to investigate the effect of 12/15 LOX inhibition on neuroinflammation process. For this purpose, two different cerebral ischemia models in mouse, permanent ischemia and ischemia/recanalization ... -
The Effect of Hyperbaric Oxygen Therapy on Rhabdomyolysis-Induced Myoglobinuric Acute Renal Failure in Rats
(Taylor & Francis Ltd, 2016)Myoglobinuric acute renal failure (MARF) may develop after severe muscle injury. Heme oxygenase-1 (HO-1), a stress-response protein, has been implicated as a protective agent against MARF. We hypothesized that hyperbaric ... -
The Role Of Reactive Oxygen Species And Oxidative Stress In Carbon Monoxide Toxicity: An In-Depth Analysis
(Maney Publishing, 2014)The underlying mechanism of the central nervous system (CNS) injury after acute carbon monoxide (CO) poisoning is interlaced with multiple factors including apoptosis, abnormal inflammatory responses, hypoxia, and ...
