• A Nanomedicine Transports A Peptide Caspase-3 Inhibitor Across The Blood-Brain Barrier And Provides Neuroprotection 

      Karatas, Hulya; Aktas, Yesim; Gursoy-Ozdemir, Yasemin; Bodur, Ebru; Yemisci, Muge; Caban, Secil; Vural, Atay; Pinarbasli, Onur; Capan, Yilmaz; Fernandez-Megia, Eduardo; Novoa-Carballal, Ramon; Riguera, Ricardo; Andrieux, Karine; Couvreur, Patrick; Dalkara, Turgay (Soc Neuroscience, 2009)
      Caspases play an important role as mediators of cell death in acute and chronic neurological disorders. Although peptide inhibitors of caspases provide neuroprotection, they have to be administered intracerebroventricularly ...
    • Brachial Diparesis Due To Motor Neuronopathy As One of the Predominant Presenting Signs of Occult Small Cell Lung Carcinoma 

      Erdener, Sefik Evren; Vural, Atay; Temucin, Cagri Mesut; Ozdamar, Sevim Erdem; Nurlu, Gulay; Varli, Kubilay; Dericioglu, Nese (Japan Soc Internal Medicine, 2016)
      Sensory neuronopathy is a well-established presentation in paraneoplastic neurological syndromes that is mostly associated with small cell lung cancer and anti-Hu antibodies. Motor neuronopathy, on the other hand, is an ...
    • Bright and Dark Vessels on Stroke Imaging: Different Sides of The Same Coin? 

      Vural, Atay; Gocmen, Rahsan; Oguz, Kader Karli; Topcuoglu, Mehmet Akif; Arsava, Ethem Murat (Aves, 2016)
      PURPOSE Prominent hypointense cerebral vessels on susceptibility-weighted imaging (SWI) and the hyperintense vessel sign (HVS) on fluid-attenuated inversion recovery (FLAIR) imaging are considered as markers of compromised ...
    • Central Neurogenic Hyperventilation In Anti-Nmda Receptor Encephalitis 

      Vural, Atay; Arsava, Ethem Murat; Dericioglu, Nese; Topcuoglu, Mehmet Akif (Japan Soc Internal Medicine, 2012)
      Central neurogenic hyperventilation (CNH) is a rare condition that is generally associated with infiltrative tumors of the brainstem. Respiratory dysfunction, particularly central hypoventilation, is common in anti-N-methyl ...
    • Fulminant Central Plus Peripheral Nervous System Demyelination Without Antibodies To Neurofascin 

      Vural, Atay; Gocmen, Rahsan; Kurne, Asli Tuncer; Oguz, Kader Karli; Temucin, Cagri Mesut; Tan, Ersin; Karabudak, Rana; Meinl, Edgar; Ozdamar, Sevim Erdem (Cambridge Univ Press, 2016)
      Background: Combined central and peripheral nervous system demyelination is a rare and poorly described phenomenon. Recently, anti-neurofascin antibodies were reported to be positive in 86% of these patients in a Japanese ...
    • Identification Of Circulating Mog-Specific B Cells In Patients With Mog Antibodies 

      Winklmeier, Stephan; Schlüter, Miriam; Spadaro, Melania; Thaler, Franziska S.; Vural, Atay; Gerhards, Ramona; Macrini, Caterina; Mader, Simone; Kurne, Aslı; Inan, Berin; Karabudak, Rana; Özbay, Feyza Gül; Esendagli, Gunes; Hohlfeld, Reinhard; Kümpfel, Tania; Meinl, Edgar (2019)
      Objective To identify circulating myelin oligodendrocyte glycoprotein (MOG)-specific B cells in the blood of patients with MOG antibodies (Abs) and to determine whether circulating MOG-specific B cells are linked to levels ...
    • Striatal Neurotransmitter Release-Related Presynaptic Proteins In L-Dopa Induced Dyskinesia In A Model Of Parkinsonism 

      Yalcin Cakmakli, Gul; Vural, Atay; Eren Kocak, Emine; Elibol, Bulent; Saka, Esen (Aves, 2018)
      Introduction: In Parkinson's disease, L-dopa-induced dyskinesia (LID) and motor fluctuations incapacitate patients as much as the disease itself. Many studies demonstrated that postsynaptic alterations and striatal synaptic ...
    • The Glycosylation Site Of Myelin Oligodendrocyte Glycoprotein Affects Autoantibody Recognition In A Large Proportion Of Patients 

      Marti Fernandez, Iris; Macrini, Caterina; Krumbholz, Markus; Hensbergen, Paul J.; Hipgrave Ederveen, Agnes L.; Winklmeier, Stephan; Vural, Atay; Kurne, Asli; Jenne, Dieter; Kamp, Frits; Gerdes, Lisa Ann; Hohlfeld, Reinhard; Wuhrer, Manfred; Kümpfel, Tania; Meinl, Edgar (2019)
      Autoantibodies to myelin oligodendrocytes glycoprotein (MOG) are found in a fraction of patients with inflammatory demyelination and are detected with MOG-transfected cells. While the prototype anti-MOG mAb 8-18C5 and ...