Autoinflammatory diseases are diseases that emerge from the abnormalities in the innate immune system of the individuals. In the crisis times, one of the mostly seen symptom is the high amount of inflammation biomarkers. ...

The discovery of new drug candidate molecules is an important step in the process of drug development. Deep generative learning, a frequently used approach in the field of artificial intelligence in recent years, has emerged ...

Pancreatic cancer is the 11th most common cancer worldwide. Five-year survival of lung, colon and stomach cancers, which are the top three in cancer related deaths, are 19%, 65% and 20%, respectively. Although pancreatic ...

Mechanistic target of rapamycin (mTOR) is a conserved serine/threonine kinase important in cell proliferation, growth and protein translation. Rapamycin, a well‑known anti‑cancer agent and immunosuppressant drug, inhibits ...

Proteins are vital for cellular processes, and accurately determining their functions is crucial for understanding complex biological mechanisms. Computational approaches have emerged as alternatives to expensive and ...

Cancer is one of the leading causes of death worldwide. The high lethality of some of the sub-types of cancer increases the importance of correct diagnosis, complete follow-up and effective treatment. Survivability in ...

Acun, H. M., Determination of Mosaicism Ratio in Copy Number Variations Using Microarray Based Genotype Information, Hacettepe University Graduate School of Health Sciences Department of Bioinformatics Master’s Thesis, ...

Assessing the best treatment option specifically for each patient is the main goal of precision medicine. The patients with the same diagnosis may display varying sensitivity to the applied treatment due to genetic ...