Tür "info:eu-repo/semantics/doctoralThesis" Nanoteknoloji ve Nanotıp Bölümü Tez Koleksiyonu için listeleme
Toplam kayıt 52, listelenen: 21-40
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Kanser Tedavisinde Gen Taşıyıcı Olarak Kendiliğinden Düzenlenen Peptit Nanopartiküllerin Hazırlanması ve Karakterizasyonu
(Fen Bilimleri Enstitüsü, 2018-02-15)All complex and functional constituents of nature result from self assembly of molecules in thermodynamically stable manner. Production of functional nanomaterials with molecular self-assembly mechanism based on bottom-up ... -
KANSER TEDAVİSİNDE KULLANILMAK ÜZERE İPEK PROTEİN NANOPARTİKÜLLERİN HAZIRLANMASI VE KARAKTERİZASYONU
(Fen Bilimleri Enstitüsü, 2018-02)For the treatment of cancer in recent years, new generation methods are being developed by directly targeting of cancer cells, thereby preventing damage to healthy tissue. siRNA therapies are one of the new generation ... -
Kemik Doku Onarımı Için Hidroksiapatit Peptit Amfifil Bazlı Nanokompozit Doku İskelelerinin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2015)A part of this study was supported by 112M442 TÜBİTAK Project and Soner Çakmak was also supported by Hacettepe University Scientific Research Coordination Unit, under The International Cooperation Programme with Project ... -
Kemik Dokusunun Rejenerasyonunda Hücre Tabakalarının Farklı Uygulamaları
(Fen Bilimleri Enstitüsü, 2018)This study was supported by Hacettepe University Scientific Research Projects Coordination Unit (Project Number: 17055) and Ülkü Bozoğlu was also supported by TÜBİTAK (TÜBİTAK-2211-A). Within the scope of the presented ... -
Kuantum Noktalarının Memeli Hücrelerindeki Sitotoksik ve Genotoksik Etkileri
(Fen Bilimleri Enstitüsü, 2015)In recent years, because of the increase in the technologies and the uses of the nanomaterials, toxicology has been the subject of many researches. Despite the potential advantages of the nanoparticles (NPs), it has been ... -
L-Karnitin Yüklü Polimerik ve Lipit Bazlı Nanopartiküler Sistemlerin Hazırlanması ve İn-Vitro Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2019-06-10)L-carnitine has attracted attention in the treatment of important problems of era such as obesity, diabetes and regional slimming in recent years due to its metabolic effects that increase fat loss and muscle building in ... -
Mimetik Biyomoleküller Kullanılarak Metamalzeme Yüzeyinin Geliştirilmesi ve Meta-Biyo-Sensör Hazırlanması
(Fen Bilimleri Enstitüsü, 2019)In the scope of this thesis, the potential use of metamaterials, which have outstanding features at nano scales as an efficient transducer was presented. For this purpose, two different metamaterials such as Split Ring ... -
Modifiye Montmorillonit ve Bunların Kullanıldığı Biyobozunur Nanokompozit Tarımsal Örtü Filmlerinin Üretimi
(Fen Bilimleri Enstitüsü, 2013)This work has been accomplished with the support from SANTEZ project number 00875.STZ.2011-1 titled "Development of Biobased/Biodegradable/Compostable Nanocomposite Mulch Films". In this study, montmorillonite clay, most ... -
MRI Kontrast Arttırıcı Ajan Olarak Magnetozom ve Hsa Kaplı Demiroksit Nanopartiküllerin Karşılaştırılması
(Fen Bilimleri Enstitüsü, 2015)The efficiency of iron oxide nanoparticles, which were prepared by two different methods and used as MRI contrast enhancing agents, were identified. While one of the iron oxide nanoparticle was isolated from Magnetospirillum ... -
Nanobio-Approaches For The Detection Of Bacteria By Sers
(Fen Bilimleri Enstitüsü, 2019)The main objective of this PhD thesis is to develop nanobio-based detection/identification protocols for pathogenic bacteria. Escherichia coli (E.coli) was the main target bacteria, Staphylococcus aureus (S.aureus) and ... -
Nanoboyutlu Polimerik Miseller Sistemler İle Gen Tedavisine Yönelik Yaklaşımlar
(Fen Bilimleri Enstitüsü, 2018)Gene therapy is an effective treatment method that has received considerable attention recently in the treatment of many genetic diseases. The success of gene therapy depends on the development of an efficient carrier ... -
Nanofiber-Desenli Polimerik Membranlar: Yüzey Kimyası, Topografisi ve Hücresel Etkileşimler
(Fen Bilimleri Enstitüsü, 2014)In the presented study, two main aims were purposed. The first aim was to pattern polymeric membranes which have different chemistry by chemically and physically different nanofibers produced via electrospining technique ... -
Nanoteknoloji Bazlı İlaç Taşıma Sistemlerinin Göze İlaç Uygulamalarında, Transkleral Geçiş Üzerine Etkisinin Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2013)Chitosan nanoparticles were synthesized and bevasizumab was loaded to this chitosan nanoparticles in the present thesis. Characterization of bevacizumab loaded chitosan nanoparticles were made and the size of the bevacizumab ... -
Nanoteknolojik Yaklaşımlarla Koagülatif Sistemlerin Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2015)Uncontrolled bleeding is the major cause of death in cases like war and disaster in addition of bleeding dependant trauma encountered in daily life. Effective bleeding control is essential because a lot of injured patients ... -
Ortopedik İmplantların Nanoteknolojik Yaklaşımlarla Fonksiyonelleştirilmesi
(Fen Bilimleri Enstitüsü, 2013)In thesis study, surface modifications were carried out on titanium and titanium based alloys, which are used in orthopaedic implant and fixators, for the purpose of enhancing of the biocompatibility and bioactivity. New ... -
Östradiol Tanıma Bölgelerine Sahip Yüzey Plazmon Rezonans Sensörlerin Hazırlanması
(Fen Bilimleri Enstitüsü, 2014)The aim of this study is the preparation of 17-β-estradiol (E2) imprinted surface plasmon resonance sensor for detecting E2. Fort this reason, SPR biosensors were modified with allyl mercaptane and the orientation of allyl ... -
Partikül Bazlı Sıvı Kromatografisi Kolonlarında Transport Modellerinin Kaşılaştırmalı Olarak İncelenmesi
(Fen Bilimleri Enstitüsü, 2019-06-17)Within the scope of the thesis, the Ideal Model (IM), Equilibrium Dispersive Model (EDM) and Random Walk Model (RWM) which are used in the literature as transport models for high performance liquid chromatography (HPLC) ... -
PATOJENİK BAKTERİLERİN TANISI İÇİN NANOESASLI SENSOR PLATFORMLARI
(Fen Bilimleri Enstitüsü, 2017-09-11)In the first part of this study, chitosan-graft-PCL (CS-g-PCL) copolymers and PCL polymer were synthesized. For grafting of PCL oligomers on the chitosan chains, chitosan was dissolved in acidic solvent (Methane sulfonic ... -
pGITRL Aktarılan Mezenkimal Kök Hücrelerin Küçük Hücreli Akciğer Kanserine in Vitro Etkisi ve Altın Nanopartiküllerle İşaretlenmesi
(Fen Bilimleri Enstitüsü, 2015)Glucocorticoid induced tumor necrosis factor receptor (GITR) and its ligand GITRL are members of tumor necrosis factor (TNF) family members. GITR and GITRL found in many cells of cancer microenvironment and can modulate ... -
POLİKATYONİK AMFİFİLİK SİKLODEKSTRİN NANOPARTİKÜLLERİN ANTİKANSER İLAÇ TAŞIYICI SİSTEM OLARAK ETKİNLİK VE GÜVENLİK AÇISINDAN DEĞERLENDİRİLMESİ
(Fen Bilimleri Enstitüsü, 2018-01-10)Nanoparticulate drug delivery systems possess advantages in cancer treatment due to their physicochemical properties. Several polymers have been used to prepare nanoparticles. Cyclodextrins, are natural oligosaccharides. ...