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Toplam kayıt 15, listelenen: 1-10
L-Karnitin Yüklü Polimerik ve Lipit Bazlı Nanopartiküler Sistemlerin Hazırlanması ve İn-Vitro Değerlendirilmesi
(Fen Bilimleri Enstitüsü, 2019-06-10)
L-carnitine has attracted attention in the treatment of important problems of era such as obesity, diabetes and regional slimming in recent years due to its metabolic effects that increase fat loss and muscle building in ...
Escherichia Coli ve Salmonella Enteritidis Tayinine Yönelik Yatay Akış Analiz Sistemi Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)
In recent years, rapid and accurate detection of pathogenic bacteria has been a current
research area in terms of public health and food safety. One of the effective methods for
this purpose is Surface-enhanced Raman ...
Nanobio-Approaches For The Detection Of Bacteria By Sers
(Fen Bilimleri Enstitüsü, 2019)
The main objective of this PhD thesis is to develop nanobio-based detection/identification protocols for pathogenic bacteria. Escherichia coli (E.coli) was the main target bacteria, Staphylococcus aureus (S.aureus) and ...
The Role Of Glutathione-S-Transferase In Epithelial Mesenchymal Transition (Emt) Model In Colorectal Cancer And The Enhancement Of Adjuvant Therapy By Targeting Glutathione-S-Transferase Inhibitor
(Fen Bilimleri Enstitüsü, 2019)
Colorectal cancer is the third leading cause of cancer-related deaths worldwide. For colorectal cancers that have not spread to distant sites, surgery is usually the primary or first treatment option. However, chemotherapy ...
İçi Boşluklu Gözenekli Silika Nanopartiküllerin İlaç Taşıyıcı Sistem Olarak Hazırlanması ve İncelenmesi
(Fen Bilimleri Enstitüsü, 2019)
In this thesis, designing a drug delivery system with high drug loading capacity due to it’s hollow interior, effective drug delivery by endosomal escape with proton-sponge effect and elongated blood circulation time to ...
Nanomodifiyeli Kardiyopleji Solüsyonunun Miyokard Korunmasındaki Etkisinin Gözlenmesi
(Fen Bilimleri Enstitüsü, 2019)
In this thesis study, the effects of cardioplegia solutions modified with Poly(2-hydroxyethyl methacrylate) (PHEMA) and Poly(2-hydroxyethyl methacrylate) - N-methacryloyl-L-histidine methyl ester (PHEMAH) nanoparticles on ...
Nükleotid Saflaştırılması İçin Baskılanmış Manyetik Poli(Hidroksietil Metakrilat) (Mphema) Nanoküreler
(Fen Bilimleri Enstitüsü, 2019)
Nucleotides and nucleosides participate in other metabolic functions because they are part of the biosynthetic pathways and play an important role as biological regulators. Nucleotides in various forms play an important ...
Mimetik Biyomoleküller Kullanılarak Metamalzeme Yüzeyinin Geliştirilmesi ve Meta-Biyo-Sensör Hazırlanması
(Fen Bilimleri Enstitüsü, 2019)
In the scope of this thesis, the potential use of metamaterials, which have outstanding features at nano scales as an efficient transducer was presented. For this purpose, two different metamaterials such as Split Ring ...
İntratümöral Uygulamaya Yönelik Nanolipozom Formülasyonlarının Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2019)
Purpose of our thesis; it has been aimed to prepare injectable formulations of the chemotherapeutic agent, which is effective in cancer cells, into nanoliposomes and to develop an intratumorally effective treatment approach. ...
Partikül Bazlı Sıvı Kromatografisi Kolonlarında Transport Modellerinin Kaşılaştırmalı Olarak İncelenmesi
(Fen Bilimleri Enstitüsü, 2019-06-17)
Within the scope of the thesis, the Ideal Model (IM), Equilibrium Dispersive Model (EDM) and Random Walk Model (RWM) which are used in the literature as transport models for high performance liquid chromatography (HPLC) ...