Browsing Biyomühendislik Bölümü Tez Koleksiyonu by Title
Now showing items 79-96 of 96
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Salinomisin ve BnHAp Yüklü Doku İskelelerinin Antikanserojen ve Antibakteriyel Etkinliğinin Araştırılması
(Fen Bilimleri Enstitüsü, 2018)In the scope of the thesis, it is aimed to investigate the synergistic effect of an anticancer drug, salinomycin, loaded poly (lactic-co-glycolic acid) (PLGA 65:35) nanoparticles with the boron doped nanohydroxyapatite ... -
SALİNOMİSİN ve BnHAp YÜKLÜ DOKU İSKELELERİNİN ANTİKANSEROJEN ve ANTİBAKTERİYEL ETKİNLİĞİNİN ARAŞTIRILMASI
(Fen Bilimleri Enstitüsü, 2018)In the scope of the thesis, it is aimed to investigate the synergistic effect of an anticancer drug, salinomycin, loaded poly (lactic-co-glycolic acid) (PLGA 65:35) nanoparticles with the boron doped nanohydroxyapatite ... -
Selection and Validation of Aptamers Against Osteosarcoma By Cell-Selex Method
(Fen Bilimleri Enstitüsü, 2019)Osteosarcoma is known as the most common malignant mesenchymal stem cell development by endochondral ossification. Treatment resulting from an early diagnosis of such aggressive pediatric bone cancer can greatly increase ... -
Serpınb1 Ve Serpınb2 Proteaz İnhibitörlerinin Bronş Epitel Hücrelerindeki İnflamatuvar Cevaptaki Rolü
(Fen Bilimleri Enstitüsü, 2018)Asthma is a serious health problem affecting nearly 300 million people worldwide. Asthma frequency varies based on countries and even based on regions of same country. For example, Australia and New Zealand have a frequency ... -
Sferoid Yüklü Ecm-Mimetik Peptit Amfifil Hidrojellerle Çip-Üstü-Karaciğer Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2018-06-28)This study was financially supported by Hacettepe University Scientific Research Projects Coordination Unit with a project entitled “Development of the liver-on-chip to be used in determining the toxicity of drugs” (project ... -
Sklera Hasarlarının Rekonstruksiyonunda Otojenik, Allojenik Ve Zenojenik Greftlerin Karşılaştırılması: Yeni Bir Otolog Yaklaşım “Trombositten Zengin Fibrin Membran”
(Fen Bilimleri Enstitüsü, 2018)The purpose of the presented thesis was to compare the effects of xenogenic, allogenic and autogenic graft materials on scleral healing in the repair of scleral tissue damage. For this purpose, scleral tissue damage model ... -
SURFACE IMPRINTED SILICA PARTICLES FOR CONCANAVALIN A PURIFICATION
(Fen Bilimleri Enstitüsü, 2018-02)ABSTRACT SURFACE IMPRINTED SILICA PARTICLES FOR CONCANAVALIN A PURIFICATION Galiya RAZYM Master of Science, Department of Bioengineering Supervisor: Prof. Dr. Handan Yavuz Alagöz January 2018, 65 pages ... -
Synthesis, Characterization And Evaluation of Skin Tissue Engineering Potential of Poly(Lactic Acid)-Nanoclay Composite Scaffolds Doped with Various Boron Components
(Fen Bilimleri Enstitüsü, 2023-02-02)This study aims to investigate the characteristic features of boron (B) and nanoclay containing micro/nanocomposites and their effect on the normal human dermal fibroblast (NHDF) cells as a potential material to be used ... -
Şap Aşısı Üretiminde Kullanılan 146 S Testine Alternatif Kromatografik Yöntem Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2015)Foot and mouth disease (FMD), which is common among double-hoofed animals, is a viral and very contagious disease having a major importance in economic terms. Seen in countries as Turkey, where the disease is endemic, ... -
Tendon Doku Mühendisliği İçin Poli(Gliserol-Sebakat) (Pgs) Tabanlı Elastomerik Matrisler
(Fen Bilimleri Enstitüsü, 2018)Tendon have an important function in transferring force from muscle to bone. Tendon metabolism can change the structural properties according to the applied mechanical forces.. The natural healing mechanism after the ... -
Tiyol-Metakrilat Polimerizasyonu ile Affinite Monolitlerinin Sentezi ve Histidin İşaretli Protein İzolasyonunda Kullanımı
(Fen Bilimleri Enstitüsü, 2019-06-19)There are many methods currently available for the purification of proteins. It is important that the purification process is carried out in as little steps as possible, with high purity and in a short time. Therefore, ... -
Üreteral Stentlerde Enfeksiyon Önleyici Antibakteriyel Fırça Tipi Polimer Aşılamanın Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2013)Ureteral stent aids the flow of urine and is profoundly used in the treatment of patients with urological disorders including obstructive uropathy (urological encrustation), ureteric injury, primary or malignant carcinomas, ... -
Vitiligo Tedavisine Yönelik Pimekrolimus Yüklü Lipozom Formülasyonlarının Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2023)Pigment diseases are diseases that occur when melanocyte cells that give color to the skin are damaged by genetic, autoimmune or environmental reasons. As a result of these damage to the melanocytes, the skin color may ... -
Yapay Zeka Yöntemi ile Bölütlenmiş Karmaşık Damar Yapılarının Üç Boyutlu Biyoyazıcı ile Üretimi
(Fen Bilimleri Enstitüsü, 2022-09-05)According to the World Health Organization, heart disease is one of the leading causes of death worldwide. Computed Tomography Angiography (CTA), which is an interventional medical imaging method and very detailed images ... -
Yüzey Zenginleştirilmiş Raman Spektroskopisi (Sers) için Nano-Yaklaşım Temelli Platformların Geliştirilmesi ve Tanı Amaçlı Uygulanması
(Fen Bilimleri Enstitüsü, 2014)Surface-Enhanced Raman Spectroscopy (SERS) has attracted increasing interest as a powerful analytical tool for the detection of chemical and biological molecules since its discovery. In SERS studies, the enhancement of ... -
Yüzeylerin Titanyum Nanoçubuklar Ve Onların Altın/Gümüş İle Modifiye Formları İle Nanodesenlenmesi Ve Farklı Alanlarda Kullanılabilirliklerinin İncelenmesi
(Fen Bilimleri Enstitüsü, 2018)Nanoscience and nanotechnology transform the material science into a wide range, providing the continuous development of new nanostructured materials. A comprehensive examination of physicochemical phenomena at the nanoscale ... -
ZENGİNLEŞTİRİLMİŞ FLORESAN GÖRÜNTÜLEME İÇİN FLORESAN BOYALAR İLE ETİKETLENMİŞ İNORGANİK NANOPARTİKÜLLER
(Fen Bilimleri Enstitüsü, 2017)Fluorescence imaging, instrumentation and probe development are a versatile tool for biological and preclinical studies, with continuous improvement in performance. Sensitive perception and visualization of deep targets ... -
Β-Estradiol Yüklü Doku İskeleleri ile In-Vitro Kemik Doku Mühendisliği
(Fen Bilimleri Enstitüsü, 2013)The aim of the present study was to develop a system of 17-β estradiol (E2) loaded poly (lactic-co-glycolic acid) PLGA nanoparticles-chitosan/hydroxyapatite (HA) tissue scaffold and to investigate the in-vitro effectiveness ...