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Bir Lokal Anestezik Madde Olan Lidokain'in (2-Dıethylamıno-N-(2,6 Dımethylphenyl) Acetamıde) Etki Süresini Uzatmak için Poli Akrilat Bazlı Hidrojel Mikrokürelerin Kullanımı ve Denenmesi
(Fen Bilimleri Enstitüsü, 2013)
Local anaesthetics are used in many space, especially surgial operation in small areas. However, their effect time is short, they need to be repeated continuously and this may cause toxicity that results in many problems. ...
İlaç Salımı İçin Moleküler Baskılanmış Kriyojel Membranlar
(Fen Bilimleri Enstitüsü, 2013)
The aim of the controlled drug delivery is to release drug with a therapeutic dose to the defined part of the body. Besides that, decreasing the side effects, providing a minimum dose usage and prolonging the pharmacological ...
Development of Bacteriophage Nanoparticles for Glycomics Analysis by Genetic Engineering
(Fen Bilimleri Enstitüsü, 2014)
The study is significant because it has overcome the current bottlenecks in glycan array construction and provide a relatively inexpensive, specific and stable glycan representation method, as well as introduce a simplified ...
Yüzey Zenginleştirilmiş Raman Spektroskopisi (Sers) için Nano-Yaklaşım Temelli Platformların Geliştirilmesi ve Tanı Amaçlı Uygulanması
(Fen Bilimleri Enstitüsü, 2014)
Surface-Enhanced Raman Spectroscopy (SERS) has attracted increasing interest as a powerful analytical tool for the detection of chemical and biological molecules since its discovery. In SERS studies, the enhancement of ...
Mezenkimal Kök Hücrelerin Osteojenik Farklılaşmasının Bor Katkılı Hap-Kaplı Kitosan Doku İskelelerinde İncelenmesi
(Fen Bilimleri Enstitüsü, 2015)
The aim of the present study is to investigate in-vitro osteogenic potential of mesenchymal stem cells, isolated from two different sources (bone marrow and adipose tissue), on boron doped hydroxyapatite (HAp) coated ...
Üreteral Stentlerde Enfeksiyon Önleyici Antibakteriyel Fırça Tipi Polimer Aşılamanın Geliştirilmesi
(Fen Bilimleri Enstitüsü, 2013)
Ureteral stent aids the flow of urine and is profoundly used in the treatment of patients with urological disorders including obstructive uropathy (urological encrustation), ureteric injury, primary or malignant carcinomas, ...
Okratoksin A Tayini İçin Nanolif Kaplı Kütle Hassas Immünosensör Hazırlanması
(Fen Bilimleri Enstitüsü, 2015)
Quartz crystal microbalance (QCM) surface was coated with cellulose acetate fiber via electrospinning method for increasing the surface area. It is expected to increase the sensitivity of mass sensitive immunosensor prepared ...
Biyofiziksel ve Biyokimyasal Uyaranlarla Desteklenmiş Doku İskeleleri ile Mezenkimal Kök Hücrelerin Osteojenik Farklılaşmasının İncelenmesi
(Fen Bilimleri Enstitüsü, 2014)
The aim of this study is to investigate the osteogenic differentiation potential of mesenchymal stem cells in the presence of biophysical and biochemical stimulants by using different biomaterials. For this purpose, ...
Nanopartiküller Kullanılarak Rf ile Hipertermi
(Fen Bilimleri Enstitüsü, 2013)
Cancer is a one of the most important diseases of human being. Although a lot of progress have been achieved in the diagnosis and treatment of cancer, their current levels are not fully satisfying (Greenlee, Hill Harmon ...
Biyomimetik Yöntemle Bor Katkılı Doku İskelelerinin Geliştirilmesi ve Kemik Doku Mühendisliğindeki Etkinliklerinin Araştırılması
(Fen Bilimleri Enstitüsü, 2013)
This thesis was prepared with the support of TÜBİTAK Project, entitled Mikrodalga desteği ile Biyomimetik Hidroksiapatit (HAp)-Bor Katkılı HAp Oluşumu ve Kitosan-HAp Kemik Doku İskelelerinin Geliştirilmesi with the code ...