Bölüm "Tıbbi Farmakoloji" Dahili Tıp Bilimleri Bölümü Tez Koleksiyonu için listeleme
Toplam kayıt 14, listelenen: 1-14
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Agmatinin Deneysel Sıçan Septik Şok Modelinde Bozulmuş Vasküler Yanıta Etkisi
(Tıp Fakültesi, 2023)Sepsis is the inflammatory response of the host to pathogen. Regardless of the severity of inflammation, mortality is observed as a result of impaired hemodynamic homeostasis-mediated organ dysfunction. Therefore, treatment ... -
Electrophysiological Effects of Eslicarbazepine on Selected Nav1.6 Variants Associated with Developmental and Epileptic Encephalopathies
(Sağlık Bilimleri Enstitüsü, 2020)Major problems with the current anti-epileptic drugs (AED) are resistance, inability to modify the course of the disease and side effects profiles, which rises the need for improved AEDs for all age group of patients. ... -
Empaglı̇flozı̇nı̇n Sıçanda Lı̇popolı̇sakkarı̇t ile İndüklenmı̇ş Sepsı̇ste Akut Böbrek Hasarı Üzerı̇ne Etkı̇lerı̇nı̇n Değerlendı̇rı̇lmesı̇
(Sağlık Bilimleri Enstitüsü, 2022-12-26)Sepsis is a fatal disease that progresses with uncontrolled inflammation and acute septic renal injury and kidney failure are frequently observed in sepsis. Mortality is significantly higher in sepsis patients who ... -
Endotelin Reseptör Antagonisti Tezosentanın Sıçanda Lipopolisakkarit İle Oluşturulan Deneysel Sepsis Modelinde Kardiyak Disfonksiyon Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2019)KARA, S.C., Effect of Endothelin Receptor Antagonist Tezosentan on Cardiac Dysfunction on an Experimental Model of Sepsis Induced by Lipopolysaccharide in Rats, Hacettepe University Graduate School of Health Sciences, ... -
Farede Lipopolisakkarit ile Oluşturulan Deneysel Sepsis Modelinde Alfa-7 Nikotinik Reseptör Agonisti PNU-282987’nin, Mezenter-Portal Perfüzyon ve Organ Hasarına Etkileri
(Tıp Fakültesi, 2022)Sepsis is life-threatening organ dysfunction caused by dysregulated host response to infection. It is among the most common reasons for admission to intensive care units in worldwide. Sepsis is characterized by systemic ... -
Melatoninin Lipopolisakkarit ile İndüklenmiş Deneysel Sepsis Modelinde Sıçan Kardiyak Fonksiyonu Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2020)This present study investigated the effect of melatonin, a pleitropic endogenous antioxidant agent, on sepsis induced cardiac dysfunction. Therefore, its effect on biochemical biomarkers at the molecular level and its ... -
Omeprazolün Lipopolisakkarit ile İndüklenmiş Sıçan Sepsis Modelinde İleum, Mide Fundusu, Kolon ve Mesane Fonksiyonel Cevapları Üzerine Olan Etkileri
(Sağlık Bilimleri Enstitüsü, 2019-09)Sepsis causes an uncontrolled systemic inflammatory response to infection. Proton pump inhibitor omeprazole (OME) is known to have anti-inflammatory effects beyond the suppression of acid secretion in cells and organs. ... -
Parenteral Lipid Emülsiyonlarının Deney Fare Sepsis Modelinde Mezenterik Hipoperfüzyon, Oksidatif Stres ve Organ Hasarına Etkisi
(Sağlık Bilimleri Enstitüsü, 2020)Öz, G., Effects of Parenteral Lipid Emulsions on Mesenteric Hypoperfusion, Oxidative Stress and Organ Damage in Experimental Mouse Sepsis Model, Philosophy of Doctorate (PhD) Thesis in Medical Pharmacology, Ankara, 2020. ... -
Preeklampside ve Gestasyonel Hipertansiyonda CYP4F2, 4F3, 4A11, 2J2, 2C9, 2C19 ve Solubl Epoksit Hidrolaz Enzimlerinin Genetik Polimorfizmlerinin Etkileri
(Tıp Fakültesi, 2021)Preeclampsia and gestational hypertension (GH) are disorders that may cause morbidity and mortality in both mother and infant. The pathophysiologies of both disorders have not been clearly established. Early detection and ... -
Sağlıklı Gönüllülerde Tenofovir ile Para-Aminosalisilik Asit Arasındaki Farmakokinetik Etkileşmenin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2018)Tuberculosis has an annual incidence rate of 10 million globally. One million of these new patients are expected to be HIV(+). Tenofovir is a widely used drug in HIV treatment. para-Aminosalicylic acid is a second line ... -
Sigara Bağımlılığında Nikotinik Kolinerjik Reseptörler ve Cyp2a6, Cyp2b6, İlaç Taşıyıcı Proteini Mdr1, Nöronal Nitrik Oksit Sentaz Genetik Polimorfizmlerinin Etkileri
(Sağlık Bilimleri Enstitüsü, 2019)Smoking causes health problems. Yet, cigarette use is common because of nicotine in cigarettes which causes dependence. Currently, nicotine itself, bupropion and varenicline are used in smoking cessation therapies. Although ... -
The Effects of Acute and Chronic Diphenhydramine and Cetirizine Use on Learning and Memory in Rats
(Sağlık Bilimleri Enstitüsü, 2018)Antihistamines are one of the most widely used drug groups in various indications such as allergy, common cold and insomnia. Although these drugs are known to cause central nervous system side effects, their effects on ... -
The Effects of the Gsk-3 Inhıbıtor Tdzd-8 on Bıpolar-Lıke Behavıoral Phenotype Induced by Hıgh Fructose Corn Syrup Consumptıon in Adolescent Rats
(Sağlık Bilimleri Enstitüsü, 2018-07-09)Children and adolescents are the top consumers of high fructose corn syrup (HFCS) sweetened beverages. Even though the cardiometabolic consequences of HFCS consumption in adolescents are well characterized, the neuropsychiatric ... -
Vagal Sinir Uyarımı ve Yüksek Fruktoz Tüketiminin Sıçan Alzheimer Hastalığı Modelinde Nöropsikiyatrik Semptomlar Üzerine Etkileri
(Tıp Fakültesi, 2020-02)Neuropsychiatric symptoms (NPS) were seen in almost all patients diagnosed with Alzheimer's disease (AD) however there is no efficient drug therapy yet. In recent years, vagal nerve stimulation (VNS) has been used for ...