• Broad Igg Repertoire In Patients With Chronic Rhinosinusitis With Nasal Polyps Regulates Proinflammatory Ige Responses 

      Shamji, Mohamed H.; Thomsen, Irene; Layhadi, Janice A.; Kappen, Jasper; Holtappels, Gabriele; Sahiner, Umit; Switzer, Amy; Durham, Stephen R.; Pabst, Oliver; Bachert, Claus (2019)
      Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is often characterized by local production of polyclonal IgE idiotypes. Although tissue IgE concentrations can be in the range of several thousand kilounits per ...
    • Toward Clinically Applicable Biomarkers For Asthma: An Eaaci Position Paper 

      Diamant, Zuzana; Vijverberg, Susanne; Alving, Kjell; Bakirtas, Arzu; Bjermer, Leif; Custovic, Adnan; Dahlen, Sven-Erik; Gaga, Mina; van Wijk, Roy Gerth; Del Giacco, Stefano; Hamelmann, Eckard; Heaney, Liam G.; Heffler, Enrico; Kalayci, Omer; Kostikas, Konstantinos; Lutter, Rene; Olin, Anna-Carin; Sergejeva, Svetlana; Simpson, Angela; Sterk, Peter J.; Tufvesson, Ellen; Agache, Ioana; Seys, Sven F. (2019)
      Inflammation, structural, and functional abnormalities within the airways are key features of asthma. Although these processes are well documented, their expression varies across the heterogeneous spectrum of asthma. Type ...