Yayın tarihi için Eczacılık Teknolojisi Bölümü listeleme
Toplam kayıt 88, listelenen: 21-40
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Dendrimeric Systems And Their Applications In Ocular Drug Delivery
(2013)Ophthalmic drug delivery is one of the most attractive and challenging research area for pharmaceutical scientists and ophthalmologists. Absorption of an ophthalmic drug in conventional dosage forms is seriously limited ... -
Hemen Salım Sağlayan Kandesartan Sileksetil Tablet Formülasyonuna Tasarımla Kalite Uygulaması
(Sağlık Bilimleri Enstitüsü, 2013)It was investigated a stable formulation development, process understanding and controlling of immediate release Candesartan Cilexetil 32 mg tablet by using QbD approach. Candesartan Cilexetil is a drug substance ... -
In Vitro/In Vivo Evaluation of Dendrimeric Systems Forretinal Drug Delivery
(Sağlık Bilimleri Enstitüsü, 2014)Ocular drug delivery is still a challenge due to its complex structure with many anatomical and physiological barriers. Delivering drugs to the back of the eye is especially harder because of barriers like cornea, sclera, ... -
Effect of Locally Applied Transforming Growth Factor Beta3 on Wound Healing and Stenosis Development in Tracheal Surgery
(Daedalus Enterprises Inc, 2014)BACKGROUND: Tracheal stenosis constitutes one of the most frequently seen problems in thoracic surgery. Although many treatment modalities to prevent fibroblast proliferation, angiogenesis, or inflammation that causes ... -
Effect of Topically Applied Sildenafil Citrate on Wound Healing: Experimental Study
(Assoc Basic Medical Sci Federation Bosnia & Herzegovina Sarajevo, 2014)Wound healing is a complex process that necessitates organization of different cell types and several signalling molecules. The aim of this study is to evaluate the effect of different concentrations of sildenafil citrate, ... -
Akut Omurilik Travmalarında Kullanılmak Üzere Nöroprotektif İlaç Yüklü Nanopartiküler İlaç Taşıyıcı Sistem Geliştirilmesi
(Sağlık Bilimleri Enstitüsü, 2015)Methyl prednisolone sodium succinate (MPSS) is a very hydrophilic synthetic glucocorticoid. Although it is usually used for its antiinflammatory effects, it is still the only efficacy proven therapeutic agent which is ... -
Determination Of Regional Intestinal Permeability Of Diclofenac And Metoprolol Using A Newly-Developed And Validated High Performance Liquid Chromatographic Method
(Pharmacotherapy Group, 2015)Purpose: To develop a simple and rapid reversed-phase high performance liquid chromatographic (HPLC) method with UV detection for the simultaneous determination of diclofenac, metoprolol tartrate, phenol red and propyl ... -
Comparison Of Dissolution Profiles Of Commercially Available Lamivudine Tablets
(Dissolution Technologies, Inc, 2015)The aim of this study was to investigate the influence of dissolution medium on the in vitro release of lamivudine (100 mg) from four commercially available lamivudine tablets (one reference and three generic). Three ... -
Few Drugs Display Flip-Flop Pharmacokinetics And These Are Primarily Associated With Classes 3 And 4 Of The Bddcs
(Wiley, 2015)This study was conducted to determine the number of drugs exhibiting flip-flop pharmacokinetics following oral (p.o.) dosing from immediate-release dosage forms and if they exhibit a common characteristic that may be ... -
Preparation and Physicochemical Characterizations of Solid Lipid Nanoparticles Containing Dotap for Dna Delivery
(Scientific Technical Research Council Turkey-Tubitak, 2015)The aim of this study was to prepare and evaluate stable cationic solid lipid nanoparticles (SLNs) as colloidal carriers for gene therapy. SLNs were mainly composed of three different biocompatible and biodegradable matrix ... -
Sefiksimin Düşük Çözünürlük ve Permeabilitesinin Siklodekstrin Kompleksleri Kullanılarak Artırılması Üzerine Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2015)Cefixime(SEF) is a wide spectrum antibiotic that is included in the third generation cephalosporins group. Its oral bioavailability is reported to be 40 %. Cyclodextrins have the ability to interact with poorly water-soluble ... -
18Th European Symposium On Radiopharmacy And Radiopharmaceuticals
(2016)OP03 Selective extraction of medically-related radionuclides from proton-irradiated thorium targets, V. Radchenko, J.W. Engle, C. Roy, J. Griswold, M.F. Nortier, E.R. Birnbaum, M. Brugh, S. Mirzadeh, K. D. John, M.E. ... -
Drug Delivery Systems for Imaging And Therapy of Parkinson'S Disease
(2016)Background: Although a variety of therapeutic approaches are available for the treatment of Parkinson’s disease, challenges limit effective therapy. Among these challenges are delivery of drugs through the blood brain ... -
Antibiyotik İçeren Kuru Toz İnhaler Formülasyonu Tasarımı ve Permeabilite Çalışmaları
(Sağlık Bilimleri Enstitüsü, 2017)The aim of this thesis is to develope dry powder inhaler formulation with antibiotic and mucolytic combination to use in the treatment of the lung infection in cystic fibrosis disease. For this purpose, in this thesis, ... -
Polimerik Nanopartiküllerin Partikül Büyüklüğüne Bağlı Olarak Hücre İçine Alım Kinetikleri ve Mekanizmaları
(Sağlık Bilimleri Enstitüsü, 2017)In this study, it was aimed to investigate cellular uptake of PLGA and chitosan nanoparticles depending on particle size. For this aim, PLGA and chitosan nanoparticles were prepared by nanoprecipitation and ionic gelation ... -
Diyabetik Yara Tedavisinde Kullanılmak Üzere Nanopartiküler Statin ve Kök Hücre İçeren Doku İskelelerinin Formülasyonu ve İn Vitro/İn Vivo Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)Simvastatin has been shown to support wound healing and stem cell treatment efficacy independent of cholesterol-lowering mechanism in recent studies. Under the light of these facts, in order to provide a new treatment approach ... -
Development of Polycationic Amphiphilic Cyclodextrin Nanoparticles for Anticancer Drug Delivery
(2017)Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum of cancers. To overcome its bioavailability problems arising from very poor aqueous solubility and tendency to recrystallize upon ...