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Toplam kayıt 340, listelenen: 41-50
Metforminin Sitotoksik, Apoptotik ve Genotoksik Etkilerinin İn Vitro Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)
Metformin is a biguanide derivative
widely used in the treatment of diabetes mellitus. Recent studies have shown the
anticancer properties of metformin. The possible mechanisms of anticancer effects of
metformin have ...
Yağ Asidi Amid Hidrolaz (Faah) ve Monoaçil Gliserol Lipaz (Magl) İnhibitörlerinin Farede Deneysel Solunum Yolu İnflamasyonu Üzerindeki Etkileri
(Sağlık Bilimleri Enstitüsü, 2019-01-15)
The endocannabinoid system is a modulator of physiological functions in various biological systems including the airways. In the present study the effects of treatment with the inhibitors of endocannabinoid-degrading enzymes ...
Türkiye'de Faaliyet Gösteren İlaç Firmalarının Web Siteleri Üzerine Bir Araştırma
(Sağlık Bilimleri Enstitüsü, 2018-10-17)
Kayıran, B., A Study on Web Sites of Drug Companies in Turkey, Hacettepe University Graduate School of Health Sciences Master Thesis in Pharmacy Management and Legislation. Ankara, 2018. The Internet, which has been in use ...
The Effects of Di(2-Ethylhexyl)Phthalate on Rat Liver in Relation to Selenium Status
(Wiley-Blackwell, 2014)
This study was performed to determine the hepatotoxicity of di(2-ethylhexyl)phthalate (DEHP) in relation to selenium status. In 3-week-old Sprague-Dawley rats, selenium deficiency was induced by a 0.05 selenium mg/kg. A ...
Ankara İlinde Reçetelenen İlaçlara Bağlı İstenmeyen Etkilerin İzlenmesi ve Farmakovijilans Konusunda Farkındalığın Artırılması
(Sağlık Bilimleri Enstitüsü, 2017)
Temiz Nemutlu N. Monitoring the Unintended Effects of Prescribed Drugs in
Ankara and Improving the Awareness of Pharmacovigilance. Hacettepe University
Institute of Health Sciences, Thesis of Master ...
Piknogenol ve Kurkuminin Çeşitli Kanser Hücre Hatlarında Sisplatin Sitotoksisitesine Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017-01-13)
Pycnogenol from Pinus pinaster and curcumin from Curcuma longa L., are poliphenolic compounds and commonly used in many diseases traditionally due to their high antioxidant properties. Cisplatin, an antineoplastic agent, ...
Kojik Asit Türevi Bileşiklerin Tasarımı, Sentezi ve Melanoma Hücresine Karşı Sitotoksisiteleri ile Tirozinaz İnhibisyonu Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)
Tyrosinase is an enzyme that acts as a catalyst in the biosynthesis of melanin pigment, which is found in fungi, in plants and in animals. Overproduction and accumulation of this pigment causes hyperpigmentation, post ...
Intracellular Generation of Ros by 3,5-Dimethylaminophenol: Persistence, Cellular Response, and Impact of Molecular Toxicity
(Oxford Univ Press, 2014)
Epidemiological studies have demonstrated extensive human exposure to the monocyclic aromatic amines, particularly to 3,5-dimethylaniline, and found an association between exposure to these compounds and risk for bladder ...
Investigation of 1377C/T Polymorphism of the Toll-Like Receptor 3 Among Patients with Chronic Hepatitis B
(Canadian Science Publishing, Nrc Research Press, 2016)
The immunopathogenesis of chronic hepatitis B (CHB) has not been clarified yet. Toll-like receptors (TLR) are a receptor family that initiates immunity with exogenous-endogenous ligands and plays a role in the pathogenesis ...
Infliximab Alleviates The Mortality, Mesenteric Hypoperfusion, Aortic Dysfunction, And Multiple Organ Damage In Septic Rats
(Canadian Science Publishing, Nrc Research Press, 2017)
Tumor necrosis factor-alpha (TNF-alpha) is a pivotal mediator that triggers inflammatory process, oxidative stress, and multiple organ injury in sepsis. We investigated the effects of infliximab on survival, mesenteric ...