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Toplam kayıt 627, listelenen: 71-80
Pitavastatin Sitotoksisitesinin Serviks Kanser Hücre (Hela) Hattında Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)
Cervical cancer which is one of the most common cancer types in women throughout the world. Investigation of possible and alternative treatment methods of cervical cancer will lead to the discovery of new effective treatment ...
Bazı N-(4-Sübstitüebenziliden)-5-Fenil-1,3,4-Tiyadiazol-2-Amin Türevleri Üzerinde Çalışmalar
(Sağlık Bilimleri Enstitüsü, 2018)
In this study, 9 new compounds having 2-substituted-5-phenyl-1,3,4-thiadiazole structures were synthesized and their antifungal and antibacterial activities were evaluated. Target compounds were synthesized by reaction of ...
Metforminin Sitotoksik, Apoptotik ve Genotoksik Etkilerinin İn Vitro Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)
Metformin is a biguanide derivative
widely used in the treatment of diabetes mellitus. Recent studies have shown the
anticancer properties of metformin. The possible mechanisms of anticancer effects of
metformin have ...
Yağ Asidi Amid Hidrolaz (Faah) ve Monoaçil Gliserol Lipaz (Magl) İnhibitörlerinin Farede Deneysel Solunum Yolu İnflamasyonu Üzerindeki Etkileri
(Sağlık Bilimleri Enstitüsü, 2019-01-15)
The endocannabinoid system is a modulator of physiological functions in various biological systems including the airways. In the present study the effects of treatment with the inhibitors of endocannabinoid-degrading enzymes ...
Türkiye'de Faaliyet Gösteren İlaç Firmalarının Web Siteleri Üzerine Bir Araştırma
(Sağlık Bilimleri Enstitüsü, 2018-10-17)
Kayıran, B., A Study on Web Sites of Drug Companies in Turkey, Hacettepe University Graduate School of Health Sciences Master Thesis in Pharmacy Management and Legislation. Ankara, 2018. The Internet, which has been in use ...
Organosfatlara Maruziyet Sonrasında Oluşan Protein Eklenti Ürünlerini Tanıyan Monoklonal Antikorun Karakterizasyonu
(Sağlık Bilimleri Enstitüsü, 2018)
Organophosphorus (OP) pesticides are irreversible inhibitors of cholinesterases [acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)]. The OPs cause the acute toxic effect by covalent binding to a serine amino ...
Karbenoksolon Disodyum İçeren Nanopartikül Formülasyonlarının Tasarımı ve Kortikal Yayılan Depresyona Bağlı Migren Tedavisindeki Etkinliğinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)
Recent studies on migraine, one of the most common diseases among neurological diseases, have shown that cortical spreading depolarization waves, cause transient opening of Pannexin-1 mega channels from neuronal cell ...
Akut Miyeloblastik Lösemilerde Gen Temelli Kanser Biyobelirteçlerin Tespiti Aracılığıyla İlaç Duyarlılığı Altgruplarının Belirlenmesi ve Prognoz Ve Tedaviye Cevabın Öngörülmesi
(Sağlık Bilimleri Enstitüsü, 2018-12-18)
The aim of this study is to determine the gene-based homogeneous subgroups of acute myeloblastic leukemias using the gene expression profiles of renin angiotensin system, the determination of biomarker potentially genes ...
The Effects of Di(2-Ethylhexyl)Phthalate on Rat Liver in Relation to Selenium Status
(Wiley-Blackwell, 2014)
This study was performed to determine the hepatotoxicity of di(2-ethylhexyl)phthalate (DEHP) in relation to selenium status. In 3-week-old Sprague-Dawley rats, selenium deficiency was induced by a 0.05 selenium mg/kg. A ...
Doksorubisin ve elakridar içeren PLGA/silika hibrit nanopartiküllerin formülasyonu ve meme kanserindeki etkinliğinin değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)
Although doxorubicin is efficient alone in cancer treatment, its being a substrate of P-glycoprotein (P-gp) limits its effectiveness. Various approaches have been developed to overcome the growing resistance to these drugs. ...