Bölüm "Farmasötik Toksikoloji" Eczacılık Meslek Bilimleri Bölümü Tez Koleksiyonu için listeleme
Toplam kayıt 40, listelenen: 21-40
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Kök Hücrelerde Olası DNA Hasarı ve Onarımının İn Vitro Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2016-12-26)Stem cells provide an opportunity to analyse the effects of xenobiotic on cell viability, differentiation and cell functions. For this reason, it is suitable alternative for in vitro and in vivo methods. Evaluation of the ... -
Kurşun Maruziyeti ve Şelasyon Tedavisi Sonrası Metabolomik ve Lipidomik Analizler
(Sağlık Bilimleri Enstitüsü, 2021)Lead is a widely preferred heavy metal in the industry due to its useful physicochemical properties and it has important toxic effects. Chelation agents are used in its treatment and intravenous sodium calcium edta is one ... -
Melazma tedavisinde yeni yaklaşımlar ve olası toksik etkilerinin in vitro olarak değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Melasma is a chronic, acquired disease that results in the accumulation of brown or gray-brown melanin pigment in the epidermis layer and/or dermis layer, especially in areas where the body is more exposed to sunlight, ... -
Mermer İşçilerinde Genotoksik Etki Mekanizmalarının ve Oksidatif Stres ile İlişkili Değişikliklerin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Workers working in marble processing plants are exposed to high levels of respirable marble dust (<10 μm) in processes such as cutting, polishing, shaping. Marble dust is mainly composed of calcium carbonate and contains ... -
Metal Geri Dönüşüm Sektörü Çalışanlarında Kurşun Maruziyetinin Neopterin Düzeylerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2023)Muhammetli S., The Effect of Lead Exposure on Neopterin Levels in Metal Recycling Industry Workers, Hacettepe University Graduate School of Health Sciences Pharmacy Department of Pharmaceutical Toxicology Program Master of ... -
Metforminin Bazı Kemoterapötik İlaçlarla Etkileşmesinin İn Vitro Olarak Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2016-12-29)Metformin is an oral antidiabetic drug widely used in the treatment of type 2 diabetes mellitus. It is stated that diabetes patients have a higher risk of developing different pathologies including cancer than healthy ... -
Metforminin Sitotoksik, Apoptotik ve Genotoksik Etkilerinin İn Vitro Değerlendirilmesi.
(Sağlık Bilimleri Enstitüsü, 2018)Metformin is a biguanide derivative widely used in the treatment of diabetes mellitus. Recent studies have shown the anticancer properties of metformin. The possible mechanisms of anticancer effects of metformin have ... -
Nandrolonun Genotoksisitesinin Tek Hücre Jel Elektroforez Tekniği İle İn Vitro İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2019)Nandrolone decanoate is among the most widely used anabolic androgenic steroids (AAS) that are often abused by young people and athletes to improve muscle strength and performance. It is a subjected to control in many ... -
Piknogenol ve Kurkuminin Çeşitli Kanser Hücre Hatlarında Sisplatin Sitotoksisitesine Etkilerinin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2017-01-13)Pycnogenol from Pinus pinaster and curcumin from Curcuma longa L., are poliphenolic compounds and commonly used in many diseases traditionally due to their high antioxidant properties. Cisplatin, an antineoplastic agent, ... -
Pitavastatin Sitotoksisitesinin Serviks Kanser Hücre (Hela) Hattında Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Cervical cancer which is one of the most common cancer types in women throughout the world. Investigation of possible and alternative treatment methods of cervical cancer will lead to the discovery of new effective treatment ... -
Pitavastatinin Sisplatin ile Birlikte Antikanserojen Etkilerinin İnsan Serviks Kanser Hücrelerinde Araştırılması
(Sağlık Bilimleri Enstitüsü, 2024-01-18)Cervical cancer is one of the most widespread malignant tumors in women around the world today. Pitavastatin is a 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitor widely used to treat hypercholesterolemia and ... -
Prenatal Bisfenol A ve/veya Di-2-Etil Hekzil Ftalat Maruziyetinin Erkek Üreme Sistemi Üzerine Etkilerinin İncelenmesi.
(Sağlık Bilimleri Enstitüsü, 2018-01)Bisphenol A (BPA) and di (2-ethylhexyl) phthalate (DEHP) are chemical substances that are used in a wide variety of industrial products, with proven endocrine disrupting properties. Today, with the increasing use of these ... -
Prenatal Bisfenol A ve/veya Di-2-Etil Hekzil Ftalat Maruziyetinin Nöroendokrin Bozucu Etkilerinin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Bisphenol A (BPA) and di(2-ethylhexyl) phthalate (DEHP) are chemical substances that are widely present in the environment and known to have endocine disrupting properties. In the recent years, studies have been conducted ... -
Pterjiumda Neopterin Düzeylerinin ve Kinürenin Yolağının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2018)Kilicarslan B., Evaluation of Neopterin Levels and Kynurenine Pathway in Pterygium, Hacettepe University Institute of Health Sciences Ph.D. Thesis in Pharmaceutical Toxicology, Ankara, 2018. Pterjium is an inflammatory and ... -
Seramik İşçilerinde Mesleki Maruziyete Bağlı Olası Genotoksik Hasarın Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2017)Silicon (Si) is the second most abundant element after oxygen that was mainly found in granite, flint, quartz rocks and stones. Exposure to crystalline silica (SiO2) occurs mainly in foundry, processing of diatomaceous ... -
Serviks Kanserinde Timokinon ve Etoposid Kombinasyonunun Hücre Canlılığı Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2022). Cervical cancer is the second most common type of cancer in women, after breast cancer, that causes the death of a woman every two minutes in the world. Major treatment options include surgery, radiotherapy, and ... -
Sıklıkla Kullanılan Bitkisel Ürünlerin İlaçlar İle Olası Etkileşmelerinin Eczacılar Tarafından Farkındalıklarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019-09-19)The use of herbal medicines and nutritional supplements has been increased dramatically in many parts of the world. Since many herbal products has been sold over the internet. It is difficult to evaluate the extent of the ... -
Tiroid Hücrelerinde Bisfenol A’nın Toksik Etkileri ve Selenyum Bileşiklerinin Koruyucu Rolünün Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2019)Bisphenol A (BPA) is a chemical compound that is used in the production of polycarbonates and epoxy resins. Humans are widely exposed to this compound by oral, inhalation and dermal routes in daily life. It is known to ... -
Total Parenteral Beslenme (Tpn) Çözeltilerini Hazırlamak İçin Kullanılan Bileşenlerde Ve Tpn Çözeltilerinde Olası Alüminyum Kontaminasyonunun Araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)Inorganic toxicity awareness and research has been increasingly echoed in the scientific world with increasing exposure to metals. Aluminum (Al), which is one of the most known metals, has attracted attention with its ... -
Ülkemizde D Vitamini Reçetelemesinin ve Tüketiminin Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2021)Vitamin D is extremely important for good health and wellbeing. It plays several roles in keeping body’s cells healthy and functioning the way they should. Most people don’t get enough vitamin D, so supplements are common. ...