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Blocking Proinflammatory Cytokine Release Modulates Peripheral Blood Mononuclear Cell Response to Porphyromonas Gingivalis
(Wiley, 2013)
Background: Chronic periodontitis (CP) is an inflammatory disease in which cytokines play a major role in the progression of disease. Anti-inflammatory cytokines (interleukin 4 [IL-4] and IL-10) were reported to be absent ...
Anabolic Actions of Parathyroid Hormone during Bone Growth Are Dependent on C-Fos
(Endocrine Soc, 2002)
PTH has anabolic and catabolic actions in bone that are not clearly understood. The protooncogene c-fos and other activating protein 1 family members are critical transcriptional mediators in bone, and c-fos is up-regulated ...
Crevicular Fluid Levels Of Interleukin-8, Interleukin-17 And Soluble Intercellular Adhesion Molecule-1 After Regenerative Periodontal Therapy
(2015)
ABSTRACT Objective: The aim of this study is to evaluate the influence of regenerative periodontal therapy on clinical parameters and interleukin-8 (IL-8), IL-17 and soluble intercellular adhesion molecule-1 ...
Genetic Evidence For Plasminogen As A Shared Genetic Risk Factor Of Coronary Artery Disease And Periodontitis
(Lippincott Williams & Wilkins, 2015)
Background-Genetic studies demonstrated the presence of risk alleles in the genes ANRIL and CAMTA1/VAMP3 that are shared between coronary artery disease (CAD) and periodontitis. We aimed to identify further shared genetic ...
Parathyroid Hormone and Parathyroid Hormone-Related Protein Exert Both Pro- and Anti-Apoptotic Effects In Mesenchymal Cells
(Amer Soc Biochemistry Molecular Biology Inc, 2002)
During bone formation, multipotential mesenchymal cells proliferate and differentiate into osteoblasts, and subsequently many die because of apoptosis. Evidence suggests that the receptor for parathyroid hormone (PTH) and ...