Show simple item record

dc.contributor.authorBakhshpour, Monireh
dc.contributor.authorIdil, Neslihan
dc.contributor.authorPercin, Isik
dc.contributor.authorDenizli, Adil
dc.date.accessioned2021-06-09T06:47:10Z
dc.date.available2021-06-09T06:47:10Z
dc.date.issued2019
dc.identifier.issn2076-3417
dc.identifier.urihttp://dx.doi.org/10.3390/app9030553
dc.identifier.urihttp://hdl.handle.net/11655/24862
dc.description.abstractThe application of interconnected supermacroporous cryogels as support matrices for the purification, separation and immobilization of whole cells and different biological macromolecules has been well reported in literature. Cryogels have advantages over traditional gel carriers in the field of biochromatography and related biomedical applications. These matrices nearly mimic the three-dimensional structure of native tissue extracellular matrix. In addition, mechanical, osmotic and chemical stability of cryogels make them attractive polymeric materials for the construction of scaffolds in tissue engineering applications and in vitro cell culture, separation materials for many different processes such as immobilization of biomolecules, capturing of target molecules, and controlled drug delivery. The low mass transfer resistance of cryogel matrices makes them useful in chromatographic applications with the immobilization of different affinity ligands to these materials. Cryogels have been introduced as gel matrices prepared using partially frozen monomer or polymer solutions at temperature below zero. These materials can be produced with different shapes and are of interest in the therapeutic area. This review highlights the recent advances in cryogelation technologies by emphasizing their biomedical applications to supply an overview of their rising stars day to day.
dc.language.isoen
dc.relation.isversionof10.3390/app9030553
dc.rightsAttribution 4.0 United States
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectbioreactor
dc.subjectcell separation
dc.subjectpurification
dc.subjectscaffold
dc.subjectseparation
dc.subjectsupermacroporous cryogel
dc.subjecttissue engineering
dc.titleBiomedical Applications Of Polymeric Cryogels
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalApplied Sciences-Basel
dc.contributor.departmentKimya
dc.identifier.volume9
dc.identifier.issue3
dc.description.indexWoS
dc.description.indexScopus


Files in this item

This item appears in the following Collection(s)

Show simple item record

Attribution 4.0 United States
Except where otherwise noted, this item's license is described as Attribution 4.0 United States