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dc.contributor.authorYazici, Mutlu Uysal
dc.contributor.authorSahin, Sanliay
dc.contributor.authorAyar, Ganime
dc.contributor.authorAzili, Mujdem Nur
dc.contributor.authorKoksal, Tulin
dc.contributor.authorBayrakci, Benan
dc.date.accessioned2021-06-02T10:39:43Z
dc.date.available2021-06-02T10:39:43Z
dc.date.issued2019
dc.identifier.issn2008-2142
dc.identifier.urihttp://dx.doi.org/10.5812/ijp.85816
dc.identifier.urihttp://hdl.handle.net/11655/23807
dc.description.abstractBackground: To determine the factors affecting the development of pneumothorax in critically ill children admitted to pediatric intensive care unit (PICU). Methods: This was a single-centered retrospective case control study comparing the clinical features of mechanically ventilated patients, who developed pneumothorax with matched control cases. Results: The study screened 2850 patients admitted to the PICU over a 3 year period. Among 1140 patients who were mechanically ventilated, 4.4% (n = 50) developed pneumothorax. Median age was 24 months. Patients with pneumothorax were found to have median pediatric risk of mortality (PRISM):26, Pediatric logistic organ dysfunction (PELOD):22 and multiorgan disfuction (MODS):3 whereas in the control group they were 15.5, 12, and 3, respectively. PRISM and PELOD were significantly higher in pneumothorax group. Pneumothorax was observed on the 11.6th day of mechanical ventilation (MV). Pneumothoraxwas mainly secondary to pneumonia (n=18, 36%) and MV-related reasons (n=13, 26%). The risk of pneumothorax was higher when P-mean was > 14 cmH(2)P and tidal volume (TV) was > 10 mL/kg (P < 0.05). The mean albumin level was 2.7 g/dL in the pneumothorax group compared with 3.6 g/dL in the control group (P < 0.001). The number of days on mechanical ventilator and the duration of hospital stay were statistically significant in pneumothorax group (P < 0.05). The mortality outcome was 44% (n=22) in the pneumothorax group compared with 6.7% (n = 2) in the control group (P < 0.001). Conclusions: Pneumothorax in critically ill children was related to increased morbidity, mortality and prolonged length of stay in hospital. Higher pediatric risk of mortality (PRISM) and Pediatric logistic organ dysfunction (PELOD) scores were associated with increased risk of pneumothorax. Hypoalbuminemia as a reflection of malnutrition status of patients might be a risk factor.
dc.language.isoen
dc.relation.isversionof10.5812/ijp.85816
dc.rightsAttribution 4.0 United States
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectAlbumin
dc.subjectCritically Ill Children
dc.subjectMechanical Ventilation
dc.subjectPediatric Intensive Care Unit
dc.subjectPneumothorax
dc.titleFactors Affecting Development Of Pneumothorax In Critically Ill Children: A 3-Year Study
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalIranian Journal Of Pediatrics
dc.contributor.departmentÇocuk Sağlığı ve Hastalıkları
dc.identifier.volume29
dc.identifier.issue2
dc.description.indexWoS
dc.description.indexScopus


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Attribution 4.0 United States
Except where otherwise noted, this item's license is described as Attribution 4.0 United States