Basit öğe kaydını göster

dc.contributor.authorBilginer, Burcak
dc.contributor.authorHanalioglu, Sahin
dc.contributor.authorTurk, Cezmi Cagri
dc.contributor.authorNarin, Firat
dc.contributor.authorOguz, Kader Karli
dc.contributor.authorSoylemezoglu, Figen
dc.contributor.authorAkalan, Nejat
dc.date.accessioned2019-12-12T06:42:38Z
dc.date.available2019-12-12T06:42:38Z
dc.date.issued2017
dc.identifier.issn1019-5149
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.15780-15.1
dc.identifier.urihttp://hdl.handle.net/11655/16746
dc.description.abstractAIM: Pediatric glioblastoma (GBM) is still a topic obscurity. The aim of this study was to explore clinical, radiological and pathological features, and prognostic factors affecting the outcomes. MATERIAL and METHODS: We retrospectively reviewed our database for prognostic factors for 42 consecutive pediatric patients with histologically proven GBM treated in our hospital. RESULTS: The study reached at 20 boys and 22 girls, with a mean age of 10.2 years. Almost all patients (97.6%) had supratentorial tumors; lobar/hemispheric (68.3%), thalamic (26.8%) and suprasellar-hypothalamic region (4.8%). Total of 11/42 children had seeding metastases (mean 11.5 months) either preoperatively or postoperatively. Gross total resection (GTR) was achieved in 13 patients (30.9%) in the first surgery. Perioperative mortality and morbidity rates were 4.7% and 19%, respectively. Patients were followed for an average of 18.1 months. The median progression-free and overall survivals were 7.0 (95% CI: 5.9-8.0) and 11.0 (95% CI: 8.9-13.1) months, respectively. 1-year, 2-year and 5-year progression-free survival and overall survivals were 30.9% vs. 50.0%, 11.9% vs. 19.0%, 4.8% vs. 9.5%; respectively. CONCLUSION: Gross total resection should be safely attempted in pediatric GBM. In addition, a thorough and frequent radiological evaluation of the entire neuraxis for seeding metastases is recommended both at diagnosis and follow-ups.
dc.language.isoen
dc.publisherTurkish Neurosurgical Soc
dc.relation.isversionof10.5137/1019-5149.JTN.15780-15.1
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNeurosciences & Neurology
dc.subjectSurgery
dc.titleIs the Knowledge Pertaining to Adult Glioblastomas Enough for Pediatric Cases? Prognostic Factors in Childhood
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalTurkish Neurosurgery
dc.contributor.departmentBeyin ve Sinir Cerrahisi
dc.identifier.volume27
dc.identifier.issue2
dc.identifier.startpage279
dc.identifier.endpage288
dc.description.indexWoS
dc.description.indexScopus


Bu öğenin dosyaları:

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster