dc.contributor.author | Basgul, E | |
dc.contributor.author | Bahadir, B | |
dc.contributor.author | Celiker, V | |
dc.contributor.author | Karagoz, AH | |
dc.contributor.author | Hamaloglu, E | |
dc.contributor.author | Aypar, U | |
dc.date.accessioned | 2019-12-12T06:40:48Z | |
dc.date.available | 2019-12-12T06:40:48Z | |
dc.date.issued | 2004 | |
dc.identifier.issn | 0379-5284 | |
dc.identifier.uri | https://doi.org/ | |
dc.identifier.uri | http://hdl.handle.net/11655/16610 | |
dc.description.abstract | Objective: Immunosuppression is directly related to the degree of trauma. The aim of this study is to compare the effects of low and high intra-abdominal pressure on immune response in moderate surgical trauma. Methods: Twenty-two patients, scheduled for laparoscopic cholecystectomy, were randomly allocated to one of 2 groups according to intra-abdominal pressure: low and high intra-abdominal pressure. This study was conducted in the Hacettepe University Faculty of Medicine, Operation Room, Ankara, Turkey. Serum interleukin (IL)-2 and IL-6 levels were measured. Results: Serum IL-2 showed a significant decrease before the incision in high intra-abdominal pressure group. The increase in serum IL-6 at the end of surgery and postoperatively was lower in low intra-abdominal pressure group. Conclusion: These results, can be interpreted as the immune system, are less depressed when there is lower intra-abdominal pressure. This may have clinical implications in immunocompromised patients. | |
dc.language.iso | en | |
dc.publisher | Saudi Med J | |
dc.rights | info:eu-repo/semantics/openAccess | |
dc.subject | General & Internal Medicine | |
dc.title | Effects Of Low And High Intra-Abdominal Pressure On Immune Response In Laparoscopic Cholecystectomy | |
dc.type | info:eu-repo/semantics/article | |
dc.relation.journal | Saudi Medical Journal | |
dc.contributor.department | Anesteziyoloji ve Reanimasyon | |
dc.identifier.volume | 25 | |
dc.identifier.issue | 12 | |
dc.identifier.startpage | 1888 | |
dc.identifier.endpage | 1891 | |
dc.description.index | WoS | |