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dc.contributor.authorBektaş, Özlen
dc.contributor.authorÜner, Ayşegül
dc.contributor.authorEliaçık, Eylem
dc.contributor.authorUz, Burak
dc.contributor.authorIşık, Ayşe
dc.contributor.authorEtgül, Sezgin
dc.contributor.authorBozkurt, Süreyya
dc.contributor.authorHaznedaroğlu, İbrahim Celalettin
dc.contributor.authorGöker, Hakan
dc.contributor.authorSayınalp, Nilgün
dc.contributor.authorAksu, Salih
dc.contributor.authorDemiroğlu, Haluk
dc.contributor.authorÖzcebe, Osman İlhami
dc.contributor.authorBüyükaşık, Yahya
dc.date.accessioned2019-12-12T06:40:16Z
dc.date.available2019-12-12T06:40:16Z
dc.date.issued2016
dc.identifier.issn1300-7777
dc.identifier.urihttps://doi.org/10.4274/tjh.2014.0455
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100722/
dc.identifier.urihttp://hdl.handle.net/11655/16522
dc.description.abstractObjective: Myelodysplastic syndrome (MDS) is a clonal hematopoietic stem cell disease. Patients are at risk of developing cytopenias or progression to acute myeloid leukemia. Different classifications and prognostic scoring systems have been developed. The aim of this study was to compare the different prognostic scoring systems. Materials and Methods: One hundred and one patients who were diagnosed with primary MDS in 2003-2011 in a tertiary care university hospital’s hematology department were included in the study. Results: As the International Prognostic Scoring System (IPSS), World Health Organization Classification-Based Prognostic Scoring System (WPSS), MD Anderson Prognostic Scoring System (MPSS), and revised IPSS (IPSS-R) risk categories increased, leukemia-free survival and overall survival decreased (p<0.001). When the IPSS, WPSS, MPSS, and IPSS-R prognostic systems were compared by Cox regression analysis, the WPSS was the best in predicting leukemia-free survival (p<0.001), and the WPSS (p<0.001) and IPSS-R (p=0.037) were better in predicting overall survival. Conclusion: All 4 prognostic systems were successful in predicting overall survival and leukemia-free survival (p<0.001). The WPSS was found to be the best predictor for leukemia-free survival, while the WPSS and IPSS-R were found to be the best predictors for overall survival.
dc.relation.isversionof10.4274/tjh.2014.0455
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleComparison Of Myelodysplastic Syndrome Prognostic Scoring Systems
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion
dc.relation.journalTurkish Journal of Hematology
dc.contributor.departmentTıbbi Patoloji
dc.identifier.volume33
dc.identifier.issue2
dc.identifier.startpage119
dc.identifier.endpage126
dc.description.indexPubMed
dc.description.indexWoS
dc.description.indexScopus


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