• 2012 Revised International Chapel Hill Consensus Conference Nomenclature Of Vasculitides 

      Jennette, J. C.; Falk, R. J.; Bacon, P. A.; Basu, N.; Cid, M. C.; Ferrario, F.; Flores-Suarez, L. F.; Gross, W. L.; Guillevin, L.; Hagen, E. C.; Hoffman, G. S.; Jayne, D. R.; Kallenberg, C. G. M.; Lamprecht, P.; Langford, C. A.; Luqmani, R. A.; Mahr, A. D.; Matteson, E. L.; Merkel, P. A.; Ozen, Seza; Pusey, C. D.; Rasmussen, N.; Rees, A. J.; Scott, D. G. I.; Specks, U.; Stone, J. H.; Takahashi, K.; Watts, R. A. (Wiley-Blackwell, 2013)
    • A European Survey of Antibiotic Management of Methicillin-Resistant Staphylococcus Aureus Infection: Current Clinical Opinion and Practice 

      Dryden, M.; Andrasevic, A. T.; Bassetti, M.; Bouza, E.; Chastre, J.; Cornaglia, G.; Esposito, S.; French, G.; Giamarellou, H.; Gyssens, I. C.; Nathwani, D.; Unal, S.; Voss, A. (Wiley-Blackwell, 2010)
      Although the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) varies across Europe, healthcare-associated MRSA infections are common in many countries. Despite several national guidelines, the approach ...
    • Alpha(1)-Adrenoceptor-Mediated Contraction Of Rat Aorta Is Partly Mediated Via Transactivation Of The Epidermal Growth Factor Receptor 

      Ulu, N.; Gurdal, H.; Landheer, S. W.; Duin, M.; Guc, M. O.; Buikema, H.; Henning, R. H. (Wiley-Blackwell, 2010)
      Background and purpose: High level of plasma catecholamines is a risk factor for vascular diseases such as hypertension and atherosclerosis. Catecholamines induce hypertrophy of vascular smooth muscle through alpha(1)-ad ...
    • Atypical Aicardi-Goutieres Syndrome: Is the Wrn Locus a Modifier? 

      Lessel, Davor; Saha, Bidisha; Hisama, Fuki; Kaymakamzade, Bahar; Nurlu, Gulay; Gursoy-Oezdemir, Yasemin; Thiele, Holger; Nuernberg, Peter; Martin, George M.; Kubisch, Christian; Oshima, Junko (Wiley-Blackwell, 2014)
      We describe a 28-year-old Turkish man with consanguineous parents who presented with an aged appearance with prematurely gray hair and scleroderma-like skin, spastic paraplegia, and apparent disability. The proband and ...
    • Clinical Outcomes Of Patients With Advanced Gastrointestinal Stromal Tumors: Safety And Efficacy In A Worldwide Treatment-Use Trial Of Sunitinib 

      Reichardt, Peter; Kang, Yoon-Koo; Rutkowski, Piotr; Schuette, Jochen; Rosen, Lee S.; Seddon, Beatrice; Yalcin, Suayib; Gelderblom, Hans; Williams, Charles C; Jr.; Fumagalli, Elena; Biasco, Guido; Hurwitz, Herbert I.; Kaiser, Pamela E.; Fly, Kolette; Matczak, Ewa; Chen, Liang; Lechuga, Maria Jose; Demetri, George D. (Wiley-Blackwell, 2015)
      BACKGROUNDThe objectives of this study were to provide sunitinib to patients with gastrointestinal stromal tumor (GIST) who were otherwise unable to obtain it and to collect broad safety and efficacy data from a large ...
    • Diabetic Cardiac Autonomic Neuropathy, Inflammation And Cardiovascular Disease 

      Vinik, Aaron I.; Erbas, Tomris; Casellini, Carolina M. (Wiley-Blackwell, 2013)
      One of the most overlooked of all serious complications of diabetes is cardiovascular autonomic neuropathy. There is now clear evidence that suggests activation of inflammatory cytokines in diabetic patients and that these ...
    • Differences In Nephrotoxicity Risk And Renal Effects Among Anti-Viral Therapies Against Hepatitis B 

      Köklü, S.; Gülşen, M. T.; Tuna, Y.; Köklü, H.; Yüksel, O.; Demir, M.; Güner, R.; Doğan, Z.; Kücükazman, M.; Poyrazoğlu, O. K.; Bıyık, M.; Öztürk, N. A.; Aydoğan, T.; Çoban, S.; Kocaman, O.; Sapmaz, F.; Göktürk, S. H.; Karaca, C.; Demirezer, A.; Tanoğlu, A.; Yıldırım, B.; Altınbaş, A.; Atak, B. M.; Coşar, A. M.; Alkan, E.; Tufan, Z. K.; Kekilli, M.; Ataseven, H.; Purnak, T.; Başar, O.; Köklü, N.; Öztürk, O.; Bakkaloğlu, K.; Besisik, F.; Koçkar, C.; Arslan, S.; Unverdi, S. (Wiley-Blackwell, 2015)
      BackgroundResults are conflicting with respect to the renal effects of anti-viral agents used for hepatitis B virus infection. AimTo compare short and long-term renal effects in real-life settings and to determine risk ...
    • Emergence And Co-Infections Of West Nile Virus And Toscana Virus In Eastern Thrace, Turkey 

      Erdem, H.; Ergunay, K.; Yilmaz, A.; Naz, H.; Akata, F.; Inan, A. S.; Ulcay, A.; Gunay, F.; Ozkul, A.; Alten, B.; Turhan, V.; Oncul, O.; Gorenek, L. (Wiley-Blackwell, 2014)
      The objective of this study was to identify the impact of West Nile virus (WNV) and Toscana virus (TOSV) in febrile diseases of unknown aetiology in Eastern Thrace, Turkey; this study was conducted during August-October ...
    • Endometrial Cancer Risk Prediction Including Serum-Based Biomarkers: Results From The Epic Cohort 

      Fortner, Renee T.; Huesing, Anika; Kuehn, Tilman; Konar, Meric; Overvad, Kim; Tjonneland, Anne; Hansen, Louise; Boutron-Ruault, Marie-Christine; Severi, Gianluca; Fournier, Agnes; Boeing, Heiner; Trichopoulou, Antonia; Benetou, Vasiliki; Orfanos, Philippos; Masala, Giovanna; Agnoli, Claudia; Mattiello, Amalia; Tumino, Rosario; Sacerdote, Carlotta; Bueno-de-Mesquita, H. B(as); Peeters, Petra H. M.; Weiderpass, Elisabete; Gram, Inger T.; Gavrilyuk, Oxana; Ramon Quiros, J.; Maria Huerta, Jose; Ardanaz, Eva; Larranaga, Nerea; Lujan-Barroso, Leila; Sanchez-Cantalejo, Emilio; Butt, Salma Tuna; Borgquist, Signe; Idahl, Annika; Lundin, Eva; Khaw, Kay-Tee; Allen, Naomi E.; Rinaldi, Sabina; Dossus, Laure; Gunter, Marc; Merritt, Melissa A.; Tzoulaki, Ioanna; Riboli, Elio; Kaaks, Rudolf (Wiley-Blackwell, 2017)
      Endometrial cancer risk prediction models including lifestyle, anthropometric and reproductive factors have limited discrimina-tion. Adding biomarker data to these models may improve predictive capacity; to our knowledge, ...
    • European Expert Opinion On The Management Of Invasive Candidiasis In Adults 

      Kullberg, B. J.; Verweij, P. E.; Akova, M.; Arendrup, M. C.; Bille, J.; Calandra, T.; Cuenca-Estrella, M.; Herbrecht, R.; Jacobs, F.; Kalin, M.; Kibbler, C. C.; Lortholary, O.; Martino, P.; Meis, J. F.; Munoz, P.; Odds, F. C.; De Pauw, B. E.; Rex, J. H.; Roilides, E.; Rogers, T. R.; Ruhnke, M.; Ullmann, A. J.; Uzun, O.; Vandewoude, K.; Vincent, J. -L.; Donnelly, J. P. (Wiley-Blackwell, 2011)
      This report discusses the present status of antifungal therapy and treatment options for candidaemia, considered by experts in the field in Europe. A conference of 26 experts from 13 European countries was held to discuss ...
    • Grace And The Development Of An Education And Training Curriculum 

      Finch, R. G.; Blasi, F. B.; Verheij, T. J. M.; Goossens, H.; Coenen, S.; Loens, K.; Rohde, G.; Saenz, H.; Akova, M. (Wiley-Blackwell, 2012)
      Clin Microbiol Infect 2012; 18: E308E313 Abstract Antimicrobial resistance is a serious threat and compromises the management of infectious disease. This has particular significance in relation to infections of the respiratory ...
    • Increased Frequency Of Extremely Skewed X Chromosome Inactivation In Juvenile Idiopathic Arthritis 

      Uz, Elif; Mustafa, Chigdem; Topaloglu, Rezan; Bilginer, Yelda; Dursun, Ali; Kasapcopur, Ozgur; Ozen, Seza; Bakkaloglu, Aysin; Ozcelik, Tayfun (Wiley-Blackwell, 2009)
      Objective. Juvenile idiopathic arthritis (JIA) is a childhood rheumatic disease of unknown etiology. Two subgroups of JIA, i.e., oligoarticular and polyarticular, are thought to have an autoimmune component, and show a ...
    • Maternal Brain Response to Own Baby-Cry Is Affected by Cesarean Section Delivery 

      Swain, James E.; Tasgin, Esra; Mayes, Linda C.; Feldman, Ruth; Constable, R. Todd; Leckman, James F. (Wiley-Blackwell, 2008)
      A range of early circumstances surrounding the birth of a child affects peripartum hormones, parental behavior and infant wellbeing. One of these factors, which may lead to postpartum depression, is the mode of delivery: ...
    • Pcos Forum: Research in Polycystic Ovary Syndrome Today and Tomorrow 

      Pasquali, Renato; Stener-Victorin, Elisabet; Yildiz, Bulent O.; Duleba, Antoni J.; Hoeger, Kathleen; Mason, Helen; Homburg, Roy; Hickey, Theresa; Franks, Steve; Tapanainen, Juha S.; Balen, Adam; Abbott, David H.; Diamanti-Kandarakis, Evanthia; Legro, Richard S. (Wiley-Blackwell, 2011)
      P>Objective To summarize promising areas of investigation into polycystic ovary syndrome (PCOS) and to stimulate further research in this area. Design Summary of a conference held by international researchers in the field ...
    • Sandfly Fever Virus Activity in Central/Northern Anatolia, Turkey: First Report of Toscana Virus Infections 

      Saygan, M. B.; Aydoğan, S.; Lo, M. M.; Weidmann, M.; Dilcher, M.; Şener, B.; Hasçelik, G.; Pinar, A.; Us, D.; K., Erguenay (Wiley-Blackwell, 2011)
      Sandfly fever viruses (SFVs) cause febrile diseases as well as aseptic meningitis/encephalitis and include serotypes sandfly fever Sicilian virus (SFSV), sandfly fever Naples virus (SFNV) and Toscana virus (TOSV). Infections ...
    • Suppression of B-Cell Activation and Ige, Iga, Igg1 and Igg4 Production by Mammalian Telomeric Oligonucleotides 

      Sackesen, C.; van de Veen, W.; Akdis, M.; Soyer, O.; Zumkehr, J.; Ruckert, B.; Stanic, B.; Kalayci, O.; Alkan, S. S.; Gursel, I.; Akdis, C. A. (Wiley-Blackwell, 2013)
      Background The fine balance of immunoglobulins (Ig) E, IgG1, IgG4 and IgA in healthy production is maintained by the interaction of B cells with adaptive and innate immune response. The regulation of toll-like receptors ...
    • Virulence Genes, Antibiotic Resistance And Plasmid Profiles Of Enterococcus Faecalis And Enterococcus Faecium From Naturally Fermented Turkish Foods 

      Togay, S. Oezmen; Keskin, A. Celebi; Acik, L.; Temiz, A. (Wiley-Blackwell, 2010)
      Aim: To determine the virulence genes, antibiotic resistance and plasmid profiles of 16 Enterococcus faecium and 68 Enterococcus faecalis strains isolated from various naturally fermented foods. Methods and Results: The ...
    • Zygomycosis In Europe: Analysis Of 230 Cases Accrued By The Registry Of The European Confederation Of Medical Mycology (Ecmm) Working Group On Zygomycosis Between 2005 And 2007 

      Skiada, A.; Pagano, L.; Groll, A.; Zimmerli, S.; Dupont, B.; Lagrou, K.; Lass-Florl, C.; Bouza, E.; Klimko, N.; Gaustad, P.; Richardson, M.; Hamal, P.; Akova, M.; Meis, J. F.; Rodriguez-Tudela, J. -L.; Roilides, E.; Mitrousia-Ziouva, A.; Petrikkos, G. (Wiley-Blackwell, 2011)
      Zygomycosis is an important emerging fungal infection, associated with high morbidity and mortality. The Working Group on Zygomycosis of the European Confederation of Medical Mycology (ECMM) prospectively collected cases ...