Meme Kanserli Kadın Hastalarda Kemoterapiye Bağlı Gelişen Bulantı, Kusma ve Öğürme Üzerine Zencefil Kullanımının Etkisi

Abstract

This experimental randomized controlled study was conducted to assess the effect of ginger on chemotherapy related nausea and vomiting at Dr Abdurrahman Yurtaslan Oncology Hospital between November 2013 and April 2014. The patients diagnosed with breast cancer were treated by doxorubicin- Cyclophosphamide based treatment included to study. The research sample consisted of 60 patients in total, with 30 control patients and 30 patients as the study group, who met the research criteria and volunteered to participate in the study. All of the patients were given the standard antiemetic drugs. The patients at study group were also given oral ginger fort he first 3 days of chemotherapy. No intervention was performed in the control group except for the routine antiemetic treatment. When compared, individuals in the study group and the control group don't differ much in age, education, marital status, number of children, Body Mass Index, health insurance and occupation(p>0.05). A decrease in nausea-vomiting in the study group was observed. This decrease was found to be insignificant in the first day post-chemotherapy and significant in the following 4 days (p<0.05). Number of retchings decreased. However, this decrease was not found to be statistically significant (p>0.05). Patients in the study group and in the control group were compared in terms of acute and delayed nausea severity scores before and after the intervention. In the study group, acute and delayed nausea severity score decreased significantly after adding ginger (p<0.001). Consequently, it was determined that ginger was effective in reducing chemotherapy-related nausea-vomiting.