Browsing Kanser Enstitüsü by Issue Date
Now showing items 21-40 of 110
-
Higher Ki67 Expression Is Associates With Unfavorable Prognostic Factors and Shorter Survival in Breast Cancer
(Asian Pacific Organization Cancer Prevention, 2014)Background: The prognostic value of the Ki67 expression level is yet unclear in breast cancer. The aim of this study was to investigate the association between Ki67 expression levels and prognostic factors such as grade, ... -
Impact Of Acetylsalicylic Acid On The Clinicopathological Characteristics And Prognosis Of Patients With Invasive Breast Cancer
(Karger, 2014)Background: The impact of acetylsalicylic acid (ASA) on the clinicopathological characteristics of breast cancer has not yet been elucidated in detail; we therefore aimed to investigate the effects of ASA on the ... -
Immunohistochemical Expression of Insulin-Like Growth Factor-1, Transforming Growth Factor-Beta1, and Vascular Endothelial Growth Factor In Parathyroid Adenoma and Hyperplasia
(Medknow Publications & Media Pvt Ltd, 2014)Background: Insulin-like growth factor (IGF), transforming growth factor-beta1 (TGF-beta 1), and vascular endothelial growth factor (VEGF) are commonly studied growth factors, but little data are available on the ... -
Good Outcomes Of Patients With Stage Ib Endometrial Cancer With Surgery Alone
(Asian Pacific Organization Cancer Prevention, 2014)Background: Most patients with endometrial cancer have stage I disease. Adjuvant therapy in stage IB (formerly IC) endometrial cancer is controversial, treatment options including observation or brachytherapy/radiotherapy ... -
Serum 25-Hydroxy Vitamin D Status Is Not Related To Osteopenia/Osteoporosis Risk in Colorectal Cancer Survivors
(Asian Pacific Organization Cancer Prevention, 2014)Background: The incidence of colorectal cancer increases with vitamin D deficiency as shown in recently published studies. In addition, prospective investigations have indicated that low vitamin D levels may be associated ... -
Lung Cancer in Women: A Single Institution Experience with 50 Patients
(Asian Pacific Organization Cancer Prevention, 2014)Background: Lung cancer is the most common cause of cancer-related death worldwide. The incidence of lung cancer is aproximately 7-8 thousand percent in Turkish women. In this study, we aimed to evaluate the clinical, ... -
Adjuvan Radyoterapi Planlanan Jinekolojik Kanserli Olgularda Radyoterapi Sırasındaki Kilo Değişiklikleri ve Organ Hareketlerine Bağlı Dozimetrik Değişikliklerin İncelenmesi
(Kanser Enstitüsü, 2014)In this study, planned curative surgery and postoperative adjuvant radiotherapy (RT), 10 patient with gynecological tumors taken for planning purposes at the beginning of treatment with computed tomography (CT) taken in ... -
All-Trans Retinoik Asit (Atra) ve 1Α,25-Dihidroksivitamin D3 (Vitamin D3) ile Uyarılan Akut Miyeloid Lösemi Hücrelerinin T Hücre Yanıtları Üzerine Etkisi
(Kanser Enstitüsü, 2014)ATRA and D3 are the active metabolites of vitamin A and D, respectively. In this study, HL-60 myeloid leukemia cells were progressed through different maturation stages with ATRA, D3, LPS, and IFN-γ. For the determination ... -
Expression and Functional Analysis of Ccrl2 Atypical Chemokine Receptor Variants on Breast Cancer Cells
(Kanser Enstitüsü, 2014)The complex network of chemokines and chemokine receptors is regulated by atypical (decoy) chemokine receptors. Atypical chemokine receptors play role in the termination of inflammatory responses and CCRL2 is the newest ... -
Expression of Toll Like Receptors in Lung Cancer and Investigating Their Effect on Apoptosis
(Kanser Enstitüsü, 2014)Members of the Toll like receptors (TLRs) family play key roles in both innate and adoptive immune responses. TLRs proteins enable host to recognize a large number of pathogen associated molecular patterns such as bacterial ... -
Meme Kanseri Hücrelerinde Pı-103 Inhibitörünün Aktive Reseptör Tirozin Kinaz Ekspresyonuna Etkisinin Incelenmesi
(Kanser Enstitüsü, 2014)Oncogenic activation of PI3K/Akt/mTOR signaling pathway is frequently seen in breast cancer. Inhibition of signaling pathway by PI3K inhibitors, tyrosine kinase inhibitors and/or monoclonal antibodies causes increase in ... -
Kolon Kanserli Hastalarda Interlökin 21 ve Interlökin32 Gen Ekspesyon Düzeyleri ve Metastaz Ilişkisi
(Kanser Enstitüsü, 2014)Tumor microenvironment contains tumor cells, immune cells, stroma and stroma associated immune cells. This microenvironment of the immune system cells release chemokines and cytokines which play an important role in the ... -
Reproductive Cancer Risk Factors Among Relatives of Cancer Patients Seeking Treatment in Hacettepe University Oncology Hospital
(Kanser Enstitüsü, 2014)This study is an attempt to measure the frequency of specific gynecological cancer risk factors in female relatives of cancer patients. A cancer risk assessment questionnaire had been designed in the Department of Preventive ... -
Efficacy of Sorafenib In Advanced Differentiated and Medullary Thyroid Cancer: Experience In A Turkish Population
(Dovepress, 2014)Purpose: Chronic otitis media with effusion (OME) is the leading cause of hearing loss during childhood. In bacterial etiology of OME, the most frequent pathogens responsible are Haemophilus influenzae followed by Streptococcus ... -
Lung Cancer Screening: A Comprehensive Review of the Literature with Detailed Data
(Akad Doktorlar Yayınevi, 2014)Lung cancer still has a big proportion of cancer related deaths inspite of improvements in chemotherapeutic and surgical treatment approaches. It has a strong relationship with tobacco comsumption so that it can be regard ... -
Cancer Associated Fibroblasts Have Phenotypic and Functional Characteristics Similar To The Fibrocytes That Represent A Novel Mdsc Subset
(Taylor & Francis Inc, 2015)Circulating fibrocytes were reported to represent a novel myeloid-derived suppressor cell (MDSC) subset and they were also proposed to be involved in the tumor immune escape. This novel fibrocyte subset had a surface ... -
Metastatic Medullary Thyroid Cancer: A Dramatic Response To A Systemic Chemotherapy (Temozolomide And Capecitabine) Regimen
(Dovepress, 2015)A 40-year-old male patient presented with increasing serum levels of calcitonin and CEA. He underwent potential curative surgery for medullary thyroid carcinoma, 3 years ago and then 7 months later he had metastasectomy ... -
Psoriasiste Lipocalin 2 Spesifik Reseptörünün Immünohistokimyasal Olarak Saptanması
(2015)Amaç: Serum Lipokalin 2 (LCN2) seviyelerinin psoriasiste artmış inflamasyon için bir genel belirteç olduğu bilinmektedir. Bu çalışmada, LCN2’nin psoriatik lezyonlardaki reseptör düzeyini araştırmayı amaçladık. Yöntemler: ... -
Vücut Içerisindeki Doku Eşdeğeri Olmayan Implant Materyallerinin Yoğunluk Ayarlı Radyoterapi ve Stereotaktik Radyocerrahi Tedavilerinde Doz Dağılımına Etkisinin İncelenmesi
(Kanser Enstitüsü, 2015)Several cancer patients, who have implant and filling material in their body, are treated with radiotherapy and those materials may cause dosimetric uncertainities during treatment which may not be estimated accurately by ... -
The Effect of Inducıble Costımulatory Lıgand (Icos-Lg) Expressıng Myeloıd Leukemıa Cells on Helper T Lymphocyte Actıvatıon and Exhaustıon
(Kanser Enstitüsü, 2015)T cell exhaustion is characterized by progressive loss of cytokine production, decreased proliferation and resistance to reactivation especially upon continuous antigen stimulation. Despite being potent stimulators of ...