Temel Tıp Bilimleri Bölümü: Güncel gönderi
Toplam kayıt 791, listelenen: 41-60
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Kistik Fibrozis Hastalarında Mitokondriyal DNA Mutasyonları ile Aminoglikozit Ototoksisitesi Arasındaki İlişkinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2023)Cystic fibrosis is an autosomal recessive genetic disease seen in Caucasians and caused by mutations in the CFTR gene. Aminoglycosides used in the treatment of cystic fibrosis cause hearing loss as a side effect in patients. ... -
Investıgatıon of The In Vıtro And In Vıvo Effects of Telomere-Targeted New Drug Candıdate Compounds on Dıfferent Cancer Cell Lınes
(Sağlık Bilimleri Enstitüsü, 2023)Cancer, characterized by its heterogeneity, metastatic character, and limited treatability, stands as a leading global cause of mortality. Cancer cells elongate their telomeres through the activity of the telomerase enzyme, ... -
Sağlık Meslek Grupları Eğitiminde Mesleklerarası Eğitim ve İşbirliğine Yönelik Paydaş Görüşleri
(Sağlık Bilimleri Enstitüsü, 2023-12-06)The aim of this study is to examine the views of faculty members and students, who are the components of health education, about interprofessional collaboration (IPC) and interprofessional education (IPE). Qualitative ... -
Doksorubisin Uygulanan Üçlü Negatif Meme Kanserinde Taurinin Tümör Büyüklüğü ve Metastaz Üzerine Etkisi
(Sağlık Bilimleri Enstitüsü, 2023)Gedikli, E., The Effect of Taurine on Tumor Size and Metastasis in Triple Negative Breast Cancer Treated With Doxorubicin, Hacettepe University Graduate School of Health Sciences Physiology Program PhD Thesis, Ankara, 2023. ... -
Primer ve Sekonder İmmün Yetmezlikli Hastalarda Saptanan Sitomegalovirüs Suşlarında Gansiklovir Direncinin Genotipik Yöntemlerle Araştırılması
(Tıp Fakültesi, 2023-11-08)Firtina A, Investigation of ganciclovir resistance in cytomegalovirus strains isolated from patients with primary and secondary immunodeficiency by genotypic methods, Hacettepe University, Faculty of Medicine, Department ... -
Klinik Bacteroides fragilis Grubu İzolatlarda Enterotoksin ve Antibiyotik Direnç Genlerinin Prevalansı ve Moleküler Tiplendirme
(Tıp Fakültesi, 2023)Increasing rates of resistance to antibiotics used in the treatment of infections caused by Bacteroides fragilis group (BFG) isolates are reported worldwide. Surveillance is important as resistance profiles vary among ... -
Endometrial Stromal Hücrelerde Ovaryan Hormonlar ile CKAP4 İlişkisinin İncelenmesi
(Tıp Fakültesi, 2023)Endometrial stromal cells undergo changes in the menstrual cycle and decidualization with the effect of ovarian hormones. Disruptions in these processes may result in clinical outcomes such as infertility, recurrent pregnancy ... -
Glikoprotein Non-Metastatik Melanoma Protein B (GPNMB), Kan Glukoz Düzeyi ve Karaciğer Yağlanması Arasındaki İlişkinin İncelenmesi
(Tıp Fakültesi, 2023)Although the functions and role of GPNMB, which has been shown to be secreted from the liver and accepted as a hepatokine, and its role in energy balance are not yet known, it is thought to play a role in the ... -
Dışkı ve Mide Biyopsi Örneklerinden Helıcobacter Pylorı Enfeksiyonunun ve Klaritromisin Direncinin Moleküler Yöntemler ile Saptanması
(Tıp Fakültesi, 2022)Inal Neşe, Detection of Helicobacter pylori Infection and Clarithromycin Resistance in Stool and Gastric Biopsy Samples by Molecular Methods, Hacettepe University Faculty of Medicine, Department of Medical Microbiology, ... -
Aksaray Üniversitesi Sağlık Bilimleri Fakültesi Öğrencilerinin Afet Bilinci Algılarının ve Tutumlarının Değerlendirilmesi
(Sağlık Bilimleri Enstitüsü, 2023)Akil, K., Evaluation of Disaster Consciousness Perceptions and Attitudes of Aksaray University Faculty of Health Sciences Students. Hacettepe University, Graduate School of Health Sciences, Master of Science Thesis for ... -
Kalıtsal Metabolik Hastalıklarda Otofaji, Oksidatif Stres ve İnflamasyon İlişkisi
(Sağlık Bilimleri Enstitüsü, 2023-08)The complications such as epilepsy, cataract, hepatic failure, chronic renal disease may develop during the clinical follow-up of the patients with inherited metabolic diseases. The aim of this study is to investigate the ... -
Sitokrom P450 2c19 (Cyp2c19) Genetik Polimorfizmlerinin Ülseratif Kolit ve Crohn Hastalığındaki Etkileri
(Sağlık Bilimleri Enstitüsü, 2023)Inflammatory bowel diseases (IBD) are diseases characterized by chronic inflammation of the intestinal mucosa. Ulcerative colitis (UC) and Crohn's disease (CH) are clinical entities presenting different characteristics. ... -
Pandemi Döneminde Başkent Üniversitesi Tıp Fakültesi Öğrencilerinin Öğrenme Yaklaşımlarıyla Psikolojik Durumları Arasındaki İlişki ve Psikolojik Sağlamlığın Aracılık Rolü
(Sağlık Bilimleri Enstitüsü, 2023)In this study, it was aimed to evaluate the mediating role of resilience in the relationship between the learning approaches and psychological states of Başkent University Faculty of Medicine students during the pandemic ... -
L-arjinin ve Agmatinin İnsan NCI-H716 Hücrelerinde GLP-1 ve PYY Salgısı Üzerine Etkisi: Kalsiyum Algılayan Reseptörlerin Rolü
(Sağlık Bilimleri Enstitüsü, 2023-08-14)Agmatine is a natural polyamine produced from L-arginine by arginine decarboxylase and is abundant in foods. One of the most significant effects of glucagon like peptide-1 (GLP1) and peptide YY (PYY) hormones released ... -
Stattic ve/veya Paclitaxel’in Üçlü Negatif Meme Kanseri Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2023-08)Triple negative breast cancer (TNBC) is an invasive and metastatic cancer with aggressive progress. We aimed to investigate the in vitro and in vivo antiproliferative and in vivo antimetastatic effects of Paclitaxel, used ... -
Boruta ve Elastik Ağ Algoritmalarının Gen Seçim Performanslarının RNA Dizileme Veri Setleri Üzerinde Karşılaştırılması: Bir Monte Carlo Benzetim Çalışması
(Sağlık Bilimleri Enstitüsü, 2023-08-24)Boruta Algorithm and Determan's Algorithm in Elastic Net Generalized Linear Models were applied to select the genes that have a significant effect on the related cancer disease using eight real RNA sequencing data set ... -
Specıfyıng the Boundarıes of Gray Zone in Dıagnostıc Tests Wıth Informatıon Crıterıa
(Sağlık Bilimleri Enstitüsü, 2023-08-09)The decision-making process in medicine is a crucial subject due to the classification of subjects as healthy or diseased. Mostly, it concludes with binary outcomes, such as whether the person has a condition or not. The ... -
Cloning Putative Voltage-Gated Calcium Channel Gene in Astacus Leptodactylus and Determination of Structural and Functional Properties of Related Protein
(Sağlık Bilimleri Enstitüsü, 2023)Voltage-gated calcium channels are essential elements in development of many cellular processes like electrical signaling, contraction secretion and gene expression. There has been a fair amount of information about the ... -
Smn Eksikliğinde Rho-İlişkili Protein Kinazın (Rock) Mikrotübül Stabilitesi Üzerine Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2023-07)Spinal muscular atrophy (SMA) is one of the rare genetic diseases with an autosomal recessive inheritance. SMA is involved in both neurodegenerative and neuromuscular disease groups due to the loss of α motor neurons in ... -
Pediatrik Büyüme Eğrilerinin Model Performanslarının Gamlss Yöntemi ile İncelenmesi ve Kantil Regresyon Yöntemi ile Karşılaştırılması
(Sağlık Bilimleri Enstitüsü, 2023-07-12)Reference pediatric growth curves constructed with the help of anthropometric measurements are one of the best tools in the examination of a child's growth and development, in the early diagnosis of disease status and in ...