Başlık için Temel Tıp Bilimleri Bölümü listeleme
Toplam kayıt 776, listelenen: 636-655
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Seroprevalence Of Hantavirus And Borrelia Burgdorferi In Düzce (Turkey) Forest Villages And The Relationship With Sociodemographic Features
(2019)Background/aim Hantavirus and Borrelia burgdorferi are two zoonotic agents that pose a great risk especially for people living in forest areas. This study aimed to investigate the seroprevalence of hantavirus and B. ... -
Serotonin Geri Emilim Blokörlerinin Hemoreolojik Parametreler Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2013)Serotonin reuptake inhibitors (SSRI) are widely prescribed drugs for the therapy of major depression. SSRIs both effect on the synaptic level and increase blood serotonin level acutely. There are no detailed studies focusing ... -
Simülasyona Dayalı Eğitimde Farklı Çözümleme Yöntemlerinin Hemşirelik Öğrencilerinin Bilgi ve Performansına Etkisi
(Sağlık Bilimleri Enstitüsü, 2019-09-23)The aim of this experimental study was to evaluate the effect of different debriefing methods in simulation-based training on nursing students’ knowledge and performance. The study sample consisted of 83 second-grade nursing ... -
Sirkadiyen Ritmin Aşı ile Edinilen Bağışıklık Yanıtına Etkisinin Crıspr/Cas9 Tekniğiyle Araştırılması
(Sağlık Bilimleri Enstitüsü, 2023-06-13)Circadian rhythms are biological processes that occur through the regulation of gene expression over time. These processes influence many biological processes such as the sleep and wake cycle, hormonal release, metabolism ... -
Sitokrom P450 2c19 (Cyp2c19) Genetik Polimorfizmlerinin Ülseratif Kolit ve Crohn Hastalığındaki Etkileri
(Sağlık Bilimleri Enstitüsü, 2023)Inflammatory bowel diseases (IBD) are diseases characterized by chronic inflammation of the intestinal mucosa. Ulcerative colitis (UC) and Crohn's disease (CH) are clinical entities presenting different characteristics. ... -
Small Vessels Are A Big Problem In Neurodegeneration And Neuroprotection
(2019)The cerebral microcirculation holds a critical position to match the high metabolic demand by neuronal activity. Functionally, microcirculation is virtually inseparable from other nervous system cells under both physiological ... -
Smn Eksikliğinde Rho-İlişkili Protein Kinazın (Rock) Mikrotübül Stabilitesi Üzerine Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2023-07)Spinal muscular atrophy (SMA) is one of the rare genetic diseases with an autosomal recessive inheritance. SMA is involved in both neurodegenerative and neuromuscular disease groups due to the loss of α motor neurons in ... -
Soft Spot: The Important Zone At The Standard Posterior Portal Of Shoulder Arthroscopy
(Tubitak Scientific & Technical Research Council Turkey, 2018)Background/aim: The localization of the standard posterior portal of shoulder arthroscopy and landmarks mentioned in the literature are unclear. The purpose of this prospective cadaveric study was to determine the localization ... -
Soğuk-Hareketsizlik Stresinin Farelerin Periferal Kanındaki Yardımcı T Hücre Yanıtına Etkisi
(Sağlık Bilimleri Enstitüsü, 2014)Stress brings out a non-spesific response, modulating the immune system so blamed in pathophysiology of various diseases. Helper T (Th) lymphocytes have a central role both in acquired immune system response and in its ... -
Sosyal Ağ Analizinin Hastalık Biyobelirteçlerinin Belirlenmesinde Kullanımı
(Sağlık Bilimleri Enstitüsü, 2018)Especially, in recent years, the use of social network analysis has gained interest in biomarker discovery studies. Hybrid approaches involve social network analysis as a step of the feature selection process bring a ... -
Specıfyıng the Boundarıes of Gray Zone in Dıagnostıc Tests Wıth Informatıon Crıterıa
(Sağlık Bilimleri Enstitüsü, 2023-08-09)The decision-making process in medicine is a crucial subject due to the classification of subjects as healthy or diseased. Mostly, it concludes with binary outcomes, such as whether the person has a condition or not. The ... -
Spinal Müsküler Atrofi Hastalarının Fibroblast Kültürlerinde Mikrotübül Stabilitesinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2020)Spinal muscular atrophy (SMA), which is characterized by motor neuron loss and muscle atrophy, is a neurodegenerative disease primarily in childhood. In SMA, Survival of motor neuron 1 (SMN1) gene mutations lead to the ... -
Spinal Müsküler Atrofi Hastalığında Görülen Fenotipik Çeşitliliğin İnsülin Benzeri Büyüme Faktörleri ve Bağlayıcı Protein Düzeyleri ile İlişkisi
(Sağlık Bilimleri Enstitüsü, 2017)Yeşbek Kaymaz, A. Spinal Muscular Atrophy Phenotype Variations and Insulin Like Growth Factors/Binding Proteins. Hacettepe University Institute of Health Sciences Medical Biology Programme, Doctor of Philosophy Thesis, ... -
Spinal Müsküler Atrofi Patogenezinde Rol Alan Genetik Düzenleyicilerin İfade Analizi
(Sağlık Bilimleri Enstitüsü, 2013)Childhood- onset spinal muscular atrophy (SMA) is an autosomal recessive disorder, which leads to alpha motor neuron degeneration. Although 95-98 % of the patients have homozygous deletions in exon 7 and 8 SMN1 gene, ... -
Spinal Müsküler Atrofi'li Drosophıla Melanogaster Modelinde Rpd3 Proteini ve Histon Asetilasyon Düzeylerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2021)Histone acetylation causes relaxation of the DNA-histone interactions and transcriptional activation. It is controlled by the balance between histone acetyl transferase (HAT) enzymes which add acetyl groups to lysine amino ... -
Stattic ve/veya Paclitaxel’in Üçlü Negatif Meme Kanseri Üzerine Etkileri
(Sağlık Bilimleri Enstitüsü, 2023-08)Triple negative breast cancer (TNBC) is an invasive and metastatic cancer with aggressive progress. We aimed to investigate the in vitro and in vivo antiproliferative and in vivo antimetastatic effects of Paclitaxel, used ... -
Structural And Immunophenotypic Characterization Of High Endothelial Venules In Rat And Human Tissue
(Saudi Med J, 2004)Objective: To present additional data on high endothelial venule (HEV) structure and immunophenotype. Methods: We used the zinc iodide-osmium tetroxide technique (ZIO), which is a metallophilic fixation and staining technique ... -
"Survival Motor Nöron" Proteini Eksikliğinin Mikrotübül Pozitif Uç Proteinleri Üzerindeki Etkisinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2019)Spinal muscular atrophy (SMA) is one of the hereditary neuromuscular disease, which is caused by mutations in the Survival of motor neuron 1 (SMN1) gene. SMN deficiency primarily affects motor neurons and regulation of ... -
Susceptibility Testing of Haemophilus Influenzae - An International Collaborative Study in Quality Assessment
(W B Saunders Co Ltd, 1996)In order to compare the prevalence of antibiotic resistance in different geographical areas, it is necessary to ensure that agreement is achieved between laboratories on the assignment of strains to 'susceptible' and ...