Başlık için Temel Tıp Bilimleri Bölümü listeleme
Toplam kayıt 778, listelenen: 351-370
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Impairment Of Lipophagy By Pnpla1 Mutations Causes Lipid Droplet Accumulation In Primary Fibroblasts Of Autosomal Recessive Congenital Ichthyosis Patients
(2019)Background: Autosomal Recessive Congenital Ichthyosis (ARCI) is a group of epidermal keratinization disorders. One of the disease-associated proteins, patatin-like phospholipase domain-containing protein-1 (PNPLA1), plays ... -
Improvement of Germ Stem Cell Pool by Leptin Supplementation and Gene Editing for Male Infertility
(Sağlık Bilimleri Enstitüsü, 2020-06-12)Infertility affects up to 12-15% of sexually active couples, and male factors contribute about 30-55% of these cases. Infertility can be caused by injuries, genetic factors, exposure to toxicants, immune-suppressive and ... -
In Vitro Activity Of Caspofungin Compared To Amphotericin B, Fluconazole, And Itraconazole Against Candida Strains Isolated In A Turkish University Hospital
(Taylor & Francis Ltd, 2005)We investigated the in vitro activity of caspofungin compared to amphotericin B, fluconazole, and itraconazole against clinical strains of Candida spp. ( n = 239). Antifungal susceptibility tests were done in accordance ... -
In Vitro Activity Of Nystatin Compared With Those Of Liposomal Nystatin, Amphotericin B, And Fluconazole Against Clinical Candida Isolates
(Amer Soc Microbiology, 2002)We investigated the in vitro activity of nystatin and liposomal nystatin against 103 Candida isolates to determine the effect of both time and medium on MICs. We also compared the nystatin MICs with those of amphotericin ... -
In Vitro And In Vivo Fitness Costs Associated With Mycobacterium Tuberculosis Rpob Mutation H526D
(Future Medicine Ltd, 2017)Aim: There is controversy regarding the potential fitness costs of rifampicin (RIF) resistance-conferring mutations in the Mycobacterium tuberculosis (Mtb) rpoB gene. We characterized the pathogenicity of an Mtb RpoB H526D ... -
In Vitro Effects Of Phenytoin And Dapt On Mda-Mb-231 Breast Cancer Cells
(Oxford Univ Press, 2015)Voltage-gated sodium channel (VGSC) activity enhances cell behaviors related to metastasis, such as motility, invasion, and oncogene expression. Neonatal alternative splice form of Nav1.5 isoform is expressed in metastatic ... -
In Vitro Susceptibility Testing Methods For Caspofungin Against Aspergillus And Fusarium Isolates
(Amer Soc Microbiology, 2001)We investigated the relevance of prominent reduction in turbidity macroscopically (MIC) and formation of aberrant hyphal tips microscopically (minimum effective concentration; MEC) in measuring the in vitro activity of ... -
In Vitro Synergy Of Caspofungin And Amphotericin B Against Aspergillus And Fusarium Spp.
(Amer Soc Microbiology, 2002)We investigated the in vitro interaction of caspofungin and amphotericin B for clinical isolates of Aspergillus and Fusarium. Synergy tests were performed using the checkerboard method and following the NCCLS M38-P guidelines ... -
In What Level And How Medical Students Use Metacognition? A Case From Hacettepe University
(Elsevier Science Bv, 2010)The aim of this study is to describe in what level and how medical students use metacognition. In the study, quantitative and qualitative methods were used together, by benefiting from descriptive method. The first three ... -
Increasing Carbapenem Resistance Due To The Clonal Dissemination Of Oxacillinase (Oxa-23 And Oxa-58)-Producing Acinetobacter Baumannii: Report From The Turkish Sentry Program Sites
(Microbiology Soc, 2008)A significant increase in carbapenem-resistance rates among Acinetobacter baumannii isolates collected in two Turkish medical centres was detected in the 2000-2006 period (20-60%) by the SENTRY Antimicrobial Surveillance ... -
Influence Of Previous Provisional Cementation On The Bond Strength Between Two Definitive Resin-Based Luting And Dentin Bonding Agents And Human Dentin
(Operative Dentistry Inc, 2007)This study evaluated the effect of two different types of provisional luting agents (RelyX Temp E, eugenol-based; RelyX Temp NE, eugenol-free) on the shear bond strengths between human dentin and two different resin-based ... -
Integration of Maternal Genome into the Neonate Genome through Breast Milk Mrna Transcripts and Reverse Transcriptase
(2012)Human milk samples contain microvesicles similar to the retroviruses. These microvesicles contain mRNA transcripts and possess reverse transcriptase activity. They contain about 14,000 transcripts representing the milk ... -
Intern Doctors’ Likelihood of Speakıng Up For Patient Safety
(Sağlık Bilimleri Enstitüsü, 2019-09)Communication breakdowns make significant contributions to medical errors and adverse events in health care. Speak up about patient safety creates a safe atmosphere which is vital to keeping patients safe, preventing errors, ... -
Invasive Mould Infections In Intensive Care Units: Epidemiology, Microbiologic Diagnosis And Antifungal Resistance
(2019)Invasive fungal infections present with a rising incidence and high morbidity and mortality rates. Among these infections are those due to moulds which draw particular attention per the diagnostic difficulties and higher ... -
Investigating the Effects of Neurometabolic Disease-Causing Genes on Synapse Function in Drosophila melanogaster
(Sağlık Bilimleri Enstitüsü, 2022)Our group has identified several patients that harbor mutations in genes that hold the potential for being important players of synapse function, UNC79 and MBOAT7 being two of them. UNC79 is one of the accessory ... -
Investigation Of Antibiotic Susceptibilities Of Anaerobic Bacteria Isolated From Patients With Chronic Periodontitis
(2019)Objective: The aim of this study was to isolate anaerobic bacteria from the patients who were consulted in Department of Periodontology, Faculty of Dentistry, Hacettepe University, because of periodontal problems, and were ... -
Investigation of Effect of Nifedipine on Surgicaly Repaired Rabbit Facial Nerve Regeneration
(Aves, 2012)Objective: Neuronal survival is an important factor in the achievement of functional restitution after peripheral nerve injuries. An experimental rabbit model was used to evaluate the effect of nifedipine on the outgrowth ...