Bölüm "Tıbbi Biyokimya" Temel Tıp Bilimleri Bölümü için listeleme
Toplam kayıt 58, listelenen: 21-40
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Effects Of Clozapine And Haloperidol Treatment On Plasma Concentrations Of Androgen Hormones And Androgendependent Organ Changes In Rats
(2019)OBJECTIVES: Metabolic and endocrine adverse effects are among the most concerning unfavorable consequences of commonly used psychotropic drugs. The present research was planned to assess and determine the effects of ... -
European Views On Patients Directly Obtaining Their Laboratory Test Results
(Walter De Gruyter Gmbh, 2015)Background: Medicine is a highly professionalized endeavour, by tradition centred on the authority of physicians. Better education and the advent of the information age cater for increased demands on society in general and ... -
Evidence For The Control Of Aggrecanases By Insulin And Glucose In Alzheimer'S Disease
(Kure Iletisim Grubu A S, 2014)Objective: Alzheimer's disease (AD) is a progressive and irreversible central nervous system disease, which slowly destroys cognitive skills and memory, and eventually even the ability to handle the simplest tasks. The ... -
Genetic Polymorphism Of Manganese Superoxide Dismutase In Behcet'S Disease
(Turkish League Against Rheumatism, 2016)Objectives: This study aims to investigate the genetic association between single nucleotide mutation in mitochondrial manganese superoxide dismutase and a Behcet's disease (BD) population by using molecular techniques. ... -
Hacettepe Üniversitesi Merkez Laboratuvarı Biyokimya Analizlerinde Onay Destek Sistemi Geliştirilmesi ve Validasyonu
(Tıp Fakültesi, 2020)The autoverification (AV) system in medical laboratories is a process in which computer-based algorithms automatically take actions on laboratory test results without the need for manual intervention by laboratory employees ... -
Heat Shock Protein 60 Antibody - A New Marker For Subsequent Atrialfibrillation Development
(Saudi Med J, 2007)Objective: To examined the pre- and post-operative anti-HSP60 antibodies of serum from patients in preoperative sinus rhythm. Methods: We prospectively studied 45 consecutive patients admitted for elective CABG from 2004 ... -
Hydrogen Peroxide-Induced Oxidative Damage In Human Chondrocytes: The Prophylactic Effects Of Hypericum Perforatum Linn Extract On Deoxyribonucleic Acid Damage, Apoptosis And Matrix Remodeling By A Disintegrin-Like And Metalloproteinase With Thrombospondin Motifs Proteinases
(Turkish League Against Rheumatism, 2014)Objectives: This in vitro study aimed to examine the protective roles of Hypericum perforatum Linn (HPL) extract on cell viability, DNA damage, apoptosis and a disintegrin-like and metalloproteinase with thrombospondin ... -
Imetelstat (A Telomerase Antagonist) Exerts Off-Target Effects On The Cytoskeleton
(2013)Telomerase is a cellular ribonucleoprotein reverse transcriptase that plays a crucial role in telomere maintenance. This enzyme is expressed in approximately 90% of human tumors, but not in the majority of normal somatic ... -
In Vitro Effects Of Phenytoin And Dapt On Mda-Mb-231 Breast Cancer Cells
(Oxford Univ Press, 2015)Voltage-gated sodium channel (VGSC) activity enhances cell behaviors related to metastasis, such as motility, invasion, and oncogene expression. Neonatal alternative splice form of Nav1.5 isoform is expressed in metastatic ... -
Integration of Maternal Genome into the Neonate Genome through Breast Milk Mrna Transcripts and Reverse Transcriptase
(2012)Human milk samples contain microvesicles similar to the retroviruses. These microvesicles contain mRNA transcripts and possess reverse transcriptase activity. They contain about 14,000 transcripts representing the milk ... -
Investıgatıon of The In Vıtro And In Vıvo Effects of Telomere-Targeted New Drug Candıdate Compounds on Dıfferent Cancer Cell Lınes
(Sağlık Bilimleri Enstitüsü, 2023)Cancer, characterized by its heterogeneity, metastatic character, and limited treatability, stands as a leading global cause of mortality. Cancer cells elongate their telomeres through the activity of the telomerase enzyme, ... -
İnsan Serum Bütirilkolinesterazının Olası Lipolitik Aktivitesi-Lipid Metabolizması ile İlişkisi.
(Sağlık Bilimleri Enstitüsü, 2021-01-21)Cholinesterases (AChE and BChE) terminate acetylcholine-induced neurotransmission at cholinergic synapses in muscle-nerve junctions. We previously showed BChE expression is regulated by essential fatty acids. The similarity ... -
Kanserde İlaç Direncinin Üstesinden Gelmenin Yolları: Yeni İlaçların Tasarımı
(Ortadogu Ad Pres & Publ Co, 2010)Drug resistance in cancer treatment is one of the causes hindering success. Thus increasing the effectiveness of current drugs or designing new drugs are being tried. Two mechanisms are hold to account for drug resistance ... -
Karyojenik Bakterilerin Dental Pulpa Hücresinde Oluşturduğu Oksidatif Stresin İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2023)Caries-causing pathogenic microorganisms (cariogenic microorganisms) are the major source of pulpal inflammation and infection, and they cause the formation of reactive oxygen molecules (ROS) with the cell membrane components ... -
Kistik Fibrozis Hastalarının Alevlenme ve Remisyon Dönemleri Plazma Sfingomyelin ve Seramid Düzeylerinin Sıvı Kromatografisi-Kütle Spektrometresi ile Belirlenmesi ve Bazı İnflamasyon Belirteçleriyle İlişkisinin İncelenmesi
(Tıp Fakültesi, 2018)Cystic fibrosis (CF) is the most common autosomal recessive genetic disorder of caucaisan population. Despite the multisystemic involvement in CF, increased mucus viscosity in the lungs, deterioration of mucociliary clearance ... -
Klorofilinin Meme Kanseri Kaynaklı Metastaz Üzerine Etkilerinin Araştırılması
(Sağlık Bilimleri Enstitüsü, 2022)The development of drug resistance against chemotherapeutic agents is one of the main reasons for reducing the success of breast cancer treatment. It has been reported that the expression levels of Glutathione S-transferase ... -
Meme Kanserinde Sisplatin Hücresel Yanıtının DDB2 ve DNA Polimeraz Eta Üzerinden İncelenmesi
(Sağlık Bilimleri Enstitüsü, 2022)In this study, it was aimed to investigate the effect of administration of PNR-7-02 together with cisplatin to MCF-7 breast cancer cells on the expression of genes encoding DDB2 and DNA polymerase η proteins, which are ...